Detalhe da pesquisa
1.
Antiviral Properties and Mechanism of Action Studies of the Hepatitis B Virus Capsid Assembly Modulator JNJ-56136379.
Antimicrob Agents Chemother
; 64(5)2020 04 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32094138
2.
Design and synthesis of tetrahydropyridopyrimidine based Toll-Like Receptor (TLR) 7/8 dual agonists.
Bioorg Med Chem Lett
; 28(19): 3216-3221, 2018 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30143425
3.
Discovery of selective 2,4-diaminoquinazoline toll-like receptor 7 (TLR 7) agonists.
Bioorg Med Chem Lett
; 28(4): 711-719, 2018 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29366653
4.
Capsid Assembly Modulators Have a Dual Mechanism of Action in Primary Human Hepatocytes Infected with Hepatitis B Virus.
Antimicrob Agents Chemother
; 61(8)2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28584155
5.
Comparison of phenotypic and genotypic tropism determination in triple-class-experienced HIV patients eligible for maraviroc treatment.
J Antimicrob Chemother
; 66(2): 265-72, 2011 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21196489
6.
1a/1b subtype profiling of nonnucleoside polymerase inhibitors of hepatitis C virus.
J Virol
; 84(6): 2923-34, 2010 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-20071590
7.
HIV-1 V3 envelope deep sequencing for clinical plasma specimens failing in phenotypic tropism assays.
AIDS Res Ther
; 7: 4, 2010 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-20804564
8.
1,5-Benzodiazepine inhibitors of HCV NS5B polymerase.
Bioorg Med Chem Lett
; 19(9): 2492-6, 2009 May 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19342234
9.
1,5-benzodiazepines, a novel class of hepatitis C virus polymerase nonnucleoside inhibitors.
Antimicrob Agents Chemother
; 52(12): 4420-31, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18852280
10.
2,4-Diaminoquinazolines as Dual Toll-like Receptor (TLR) 7/8 Modulators for the Treatment of Hepatitis B Virus.
J Med Chem
; 61(14): 6236-6246, 2018 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29965759
11.
Identification and Optimization of Pyrrolo[3,2-d]pyrimidine Toll-like Receptor 7 (TLR7) Selective Agonists for the Treatment of Hepatitis B.
J Med Chem
; 60(14): 6137-6151, 2017 07 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28671847
12.
Novel Pyrimidine Toll-like Receptor 7 and 8 Dual Agonists to Treat Hepatitis B Virus.
J Med Chem
; 59(17): 7936-49, 2016 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-27513093
13.
HIV-1 nucleotide mixture detection in the virco(®)TYPE HIV-1 genotyping assay: a comparison between Sanger sequencing and 454 pyrosequencing.
J Virol Methods
; 175(1): 129-32, 2011 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-21549149
14.
Minor variant detection in amplicons using 454 massive parallel pyrosequencing: experiences and considerations for successful applications.
Biotechniques
; 51(3): 167-77, 2011 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-21906038
15.
HIV-1 dual/mixed tropic isolates show different genetic and phenotypic characteristics and response to maraviroc in vitro.
Antiviral Res
; 90(1): 42-53, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21349294
16.
Binding-site identification and genotypic profiling of hepatitis C virus polymerase inhibitors.
J Virol
; 81(13): 6909-19, 2007 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-17459932