Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros

Base de dados
Ano de publicação
Tipo de documento
País de afiliação
Intervalo de ano de publicação
1.
HIV Med ; 24(12): 1190-1197, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37772682

RESUMO

OBJECTIVE: Review the evidence on the incidence and impact of herpes zoster among people living with HIV and the potential impact of recombinant zoster vaccine for people aging with HIV. METHODS: Narrative review. RESULTS: Although antiretroviral therapy has substantially reduced the risk of herpes zoster among people living with HIV, they remain at an increased risk compared with the general population. Among people aging with HIV, aging per se is now the main risk factor for herpes zoster. Beyond pain, herpes zoster is also associated with a risk of sight-threatening complications in case of trigeminal involvement, disseminated diseases and stroke. Post-herpetic neuralgia is also a potential threat to the quality of life of people aging with HIV. The recombinant zoster vaccine has demonstrated high and sustained efficacy in the prevention of herpes zoster, post-herpetic neuralgia, and other herpes zoster complications in the general population. Immunogenicity data among people living with HIV with high CD4+ T-cell count and controlled viral load are comparable to those among the general population. Real-life effectiveness data indicate high vaccine efficacy among immunocompromised patients other than people living with HIV. High vaccine price, vaccine hesitancy, and limited disease and vaccine awareness represent potential hurdles for high vaccine uptake among people aging with HIV in Europe. CONCLUSIONS: Herpes zoster, and its complications, is a vaccine-preventable disease of aging people. Given its impact on quality of life, herpes zoster prevention using recombinant zoster vaccine is a safe strategy to be considered in every person aging with HIV.


Assuntos
Infecções por HIV , Vacina contra Herpes Zoster , Herpes Zoster , Neuralgia Pós-Herpética , Humanos , Neuralgia Pós-Herpética/prevenção & controle , Neuralgia Pós-Herpética/epidemiologia , Qualidade de Vida , Infecções por HIV/complicações , Herpes Zoster/prevenção & controle , Herpes Zoster/epidemiologia , Herpesvirus Humano 3 , Envelhecimento
2.
Eur J Case Rep Intern Med ; 10(5): 003828, 2023.
Artigo em Inglês | MEDLINE | ID: mdl-37205210

RESUMO

Behçet's syndrome is a complex vasculitis involving vessels of all sizes. The typical clinical presentation consists of recurrent oral ulcers associated with genital ulcers, and/or intra-ocular inflammation and/or cutaneous lesions. It may also involve the joints, central nervous system, cardiovascular system and gastrointestinal tract. Muscle involvement associated with Behçet's syndrome has been rarely described. We here report two cases of muscular manifestations in the setting of Behçet's syndrome with specific gastrocnemius muscle involvement. LEARNING POINTS: Behçet's syndrome (BS) is a vasculitis involving vessels of all sizes with multi-organ involvement.Myositis is a rare manifestation in the setting of BS.Musculoskeletal symptoms should be investigated in patients with BS.

SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA