Detalhe da pesquisa
1.
Multiplexed Proteome Dynamics Profiling Reveals Mechanisms Controlling Protein Homeostasis.
Cell
; 173(1): 260-274.e25, 2018 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-29551266
2.
Author Correction: Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 570(7761): E53, 2019 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-31142845
3.
Design of amidobenzimidazole STING receptor agonists with systemic activity.
Nature
; 564(7736): 439-443, 2018 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30405246
4.
Deoxycytidine kinase (dCK) inhibition is synthetic lethal with BRCA2 deficiency.
Drug Resist Updat
; 67: 100932, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36706533
5.
Characterization of Apo-Form Selective Inhibition of Indoleamine 2,3-Dioxygenase*.
Chembiochem
; 22(3): 516-522, 2021 02 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32974990
6.
Discovery and Characterisation of Highly Cooperative FAK-Degrading PROTACs.
Angew Chem Int Ed Engl
; 60(43): 23327-23334, 2021 10 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34416073
7.
Fragment-Based Covalent Ligand Screening Enables Rapid Discovery of Inhibitors for the RBR E3 Ubiquitin Ligase HOIP.
J Am Chem Soc
; 141(6): 2703-2712, 2019 02 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30657686
8.
Thermal profiling reveals phenylalanine hydroxylase as an off-target of panobinostat.
Nat Chem Biol
; 12(11): 908-910, 2016 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-27669419
9.
Drug selectivity: Running in the family.
Nat Chem Biol
; 10(8): 608-9, 2014 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-24997603
10.
A Phenotypic Approach for the Identification of New Molecules for Targeted Protein Degradation Applications.
SLAS Discov
; 26(7): 885-895, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34041938
11.
A caged E3 ligase ligand for PROTAC-mediated protein degradation with light.
Chem Commun (Camb)
; 56(41): 5532-5535, 2020 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32297626
12.
Chemical proteomics reveals target selectivity of clinical Jak inhibitors in human primary cells.
Sci Rep
; 9(1): 14159, 2019 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31578349
13.
PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding.
ACS Chem Biol
; 14(3): 342-347, 2019 03 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30807093
14.
Discovery of GSK8612, a Highly Selective and Potent TBK1 Inhibitor.
ACS Med Chem Lett
; 10(5): 780-785, 2019 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31097999
15.
Differential Kinobeads Profiling for Target Identification of Irreversible Kinase Inhibitors.
ACS Chem Biol
; 12(10): 2515-2521, 2017 10 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28876896
16.
Discovery of a Highly Selective Tankyrase Inhibitor Displaying Growth Inhibition Effects against a Diverse Range of Tumor Derived Cell Lines.
J Med Chem
; 60(13): 5455-5471, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28591512
17.
A Modular Probe Strategy for Drug Localization, Target Identification and Target Occupancy Measurement on Single Cell Level.
ACS Chem Biol
; 11(9): 2541-50, 2016 09 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-27384741
18.
Interrogating the Druggability of the 2-Oxoglutarate-Dependent Dioxygenase Target Class by Chemical Proteomics.
ACS Chem Biol
; 11(7): 2002-10, 2016 07 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27197014
19.
Cell Penetrant Inhibitors of the KDM4 and KDM5 Families of Histone Lysine Demethylases. 1. 3-Amino-4-pyridine Carboxylate Derivatives.
J Med Chem
; 59(4): 1357-69, 2016 Feb 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-26771107