Detalhe da pesquisa
1.
Arginine dependency is a therapeutically exploitable vulnerability in chronic myeloid leukaemic stem cells.
EMBO Rep
; 24(10): e56279, 2023 10 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37489735
2.
A randomised evaluation of low-dose Ara-C plus pegylated recombinant arginase BCT-100 versus low dose Ara-C in older unfit patients with acute myeloid leukaemia: Results from the LI-1 trial.
Br J Haematol
; 200(5): 573-578, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36413792
3.
Invariant NKT cells metabolically adapt to the acute myeloid leukaemia environment.
Cancer Immunol Immunother
; 72(3): 543-560, 2023 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-35962843
4.
Characterizing EBV-associated lymphoproliferative diseases and the role of myeloid-derived suppressor cells.
Blood
; 137(2): 203-215, 2021 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33443553
5.
TGF-ß orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer.
Cancer Immunol Immunother
; 71(7): 1583-1596, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-34727230
6.
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity.
Blood
; 136(10): 1155-1160, 2020 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32573723
7.
Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors.
Invest New Drugs
; 39(6): 1633-1640, 2021 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-34287772
8.
Targeting the arginine metabolic brake enhances immunotherapy for leukaemia.
Int J Cancer
; 145(8): 2201-2208, 2019 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30485425
9.
Enteroviral Encephalitis in a Child With CNS Relapse of Burkitt Leukemia Treated With Rituximab.
J Pediatr Hematol Oncol
; 41(1): e27-e29, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29315142
10.
Hemophagocytic Lymphohistiocytosis Associated With 2 Cases of Pediatric Lymphocyte-depleted Classic Hodgkin Lymphoma.
J Pediatr Hematol Oncol
; 41(5): e341-e345, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30601404
11.
The arginine metabolome in acute lymphoblastic leukemia can be targeted by the pegylated-recombinant arginase I BCT-100.
Int J Cancer
; 142(7): 1490-1502, 2018 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29168171
12.
Arginine dependence of acute myeloid leukemia blast proliferation: a novel therapeutic target.
Blood
; 125(15): 2386-96, 2015 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-25710880
13.
Molecular basis and current strategies of therapeutic arginine depletion for cancer.
Int J Cancer
; 139(3): 501-9, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26913960
14.
Adjunctive Treatment in Juvenile Nasopharyngeal Angiofibroma: How Should We Approach Recurrence?
J Pediatr Hematol Oncol
; 38(3): 235-9, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26907644
15.
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment.
Blood
; 122(5): 749-58, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23733335
16.
Disseminated Congenital Malignant Rhabdoid Tumor Misdiagnosed as Multiple Congenital Hemangiomas.
J Pediatr Hematol Oncol
; 42(1): 79-80, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31415283
17.
PARC: a phase I/II study evaluating the safety and activity of pegylated recombinant human arginase BCT-100 in relapsed/refractory cancers of children and young adults.
Front Oncol
; 14: 1296576, 2024.
Artigo
em Inglês
| MEDLINE | ID: mdl-38357205
18.
Engineering amino acid uptake or catabolism promotes CAR T-cell adaption to the tumor environment.
Blood Adv
; 7(9): 1754-1761, 2023 05 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36521029
19.
Characterisation of Expression the Arginine Pathway Enzymes in Childhood Brain Tumours to Determine Susceptibility to Therapeutic Arginine Depletion.
Biomed Res Int
; 2022: 9008685, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35782058
20.
G-CSF induces CD15+ CD14+ cells from granulocytes early in the physiological environment of pregnancy and the cancer immunosuppressive microenvironment.
Clin Transl Immunology
; 11(5): e1395, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35602884