Detalhe da pesquisa
1.
Radiosensitizing effect of a novel CTSS inhibitor by enhancing BRCA1 protein stability in triple-negative breast cancer cells.
Cancer Sci
; 115(6): 2036-2048, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38613358
2.
The miR-15b-Smurf2-HSP27 axis promotes pulmonary fibrosis.
J Biomed Sci
; 30(1): 2, 2023 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-36611161
3.
Design, synthesis, and biological evaluation of novel HSP27 inhibitors to sensitize lung cancer cells to clinically available anticancer agents.
Bioorg Chem
; 130: 106260, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36410114
4.
Synthetic TGF-ß Signaling Agonist-Treated Dendritic Cells Induce Tolerogenicity and Antirheumatic Effects.
Curr Issues Mol Biol
; 44(9): 3809-3821, 2022 Aug 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-36135173
5.
Novel TGF-ß1 inhibitor antagonizes TGF-ß1-induced epithelial-mesenchymal transition in human A549 lung cancer cells.
J Cell Biochem
; 120(1): 977-987, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30216515
6.
The synthesis and anticancer activities of chiral epoxy-substituted chromone analogs.
Bioorg Chem
; 84: 347-354, 2019 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30530076
7.
Asymmetric Synthesis of (-)-6-Desmethyl-Fluvirucinine A1 via Conformationally-Controlled Diastereoselective Lactam-Ring Expansions.
Molecules
; 23(9)2018 Sep 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30223428
8.
Conversion of Medium-Sized Lactams to α-Vinyl or α-Acetylenyl Azacycles via N,O-Acetal TMS Ethers.
Molecules
; 23(11)2018 Nov 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30463260
9.
Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles.
J Pineal Res
; 63(3)2017 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-28658519
10.
The Conjugated Double Bond of Coniferyl Aldehyde Is Essential for Heat Shock Factor 1 Mediated Cytotoprotection.
J Nat Prod
; 80(8): 2379-2383, 2017 08 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28737916
11.
Effect of chlorine substituent on cytotoxic activities: Design and synthesis of systematically modified 2,4-diphenyl-5H-indeno[1,2-b]pyridines.
Bioorg Med Chem Lett
; 26(7): 1726-31, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26927425
12.
Synthesis and topoisomerases inhibitory activity of heteroaromatic chalcones.
Bioorg Med Chem
; 24(22): 5921-5928, 2016 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27707625
13.
Synthesis and biological evaluation of 2-phenol-4-chlorophenyl-6-aryl pyridines as topoisomerase II inhibitors and cytotoxic agents.
Bioorg Chem
; 66: 145-59, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27174797
14.
Topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of dihydroxylated 2,6-diphenyl-4-aryl pyridines.
Bioorg Med Chem
; 23(13): 3638-54, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25936262
15.
Synthesis, topoisomerase I and II inhibitory activity, cytotoxicity, and structure-activity relationship study of 2-phenyl- or hydroxylated 2-phenyl-4-aryl-5H-indeno[1,2-b]pyridines.
Bioorg Med Chem
; 23(13): 3499-512, 2015 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26022080
16.
Design and synthesis of conformationally constrained hydroxylated 4-phenyl-2-aryl chromenopyridines as novel and selective topoisomerase II-targeted antiproliferative agents.
Bioorg Med Chem
; 23(19): 6454-66, 2015 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26361737
17.
Ethyl 2-(benzylidene)-7-methyl-3-oxo-2,3-dihydro-5H-thiazolo[3,2-a]pyrimidine-6-carboxylate analogues as a new scaffold for protein kinase casein kinase 2 inhibitor.
Bioorg Med Chem
; 22(17): 4553-65, 2014 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-25131958
18.
Chalcones, inhibitors for topoisomerase I and cathepsin B and L, as potential anti-cancer agents.
Bioorg Med Chem Lett
; 23(11): 3320-4, 2013 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23608763
19.
Synthesis and investigation of dihydroxychalcones as calpain and cathepsin inhibitors.
Bioorg Chem
; 51: 24-30, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-24095934
20.
Synthesis and evaluation of 7-(3-aminopropyloxy)-substituted flavone analogue as a topoisomerase IIα catalytic inhibitor and its sensitizing effect to enzalutamide in castration-resistant prostate cancer cells.
Eur J Med Chem
; 246: 114999, 2023 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36493620