Detalhe da pesquisa
1.
Whole-genome CRISPR screening identifies PI3K/AKT as a downstream component of the oncogenic GNAQ-focal adhesion kinase signaling circuitry.
J Biol Chem
; 299(2): 102866, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36596361
2.
PolyG-DS: An ultrasensitive polyguanine tract-profiling method to detect clonal expansions and trace cell lineage.
Proc Natl Acad Sci U S A
; 118(31)2021 08 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34330826
3.
Accurate genome-wide genotyping from archival tissue to explore the contribution of common genetic variants to pre-cancer outcomes.
J Transl Med
; 20(1): 623, 2022 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36575447
4.
Targeted genome fragmentation with CRISPR/Cas9 enables fast and efficient enrichment of small genomic regions and ultra-accurate sequencing with low DNA input (CRISPR-DS).
Genome Res
; 28(10): 1589-1599, 2018 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-30232196
5.
Characterization of TP53 mutations in Pap test DNA of women with and without serous ovarian carcinoma.
Gynecol Oncol
; 156(2): 407-414, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31839337
6.
Tumor microenvironmental determinants of high-risk DCIS progression.
Res Sq
; 2024 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-38766192
7.
Adopting duplex sequencing technology for genetic toxicity testing: A proof-of-concept mutagenesis experiment with N-ethyl-N-nitrosourea (ENU)-exposed rats.
Mutat Res Genet Toxicol Environ Mutagen
; 891: 503669, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37770135
8.
Adopting Duplex Sequencing™ Technology for Genetic Toxicity Testing: A Proof-of-Concept Mutagenesis Experiment with N-Ethyl-N-Nitrosourea (ENU)-Exposed Rats.
bioRxiv
; 2023 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37214853
9.
Integrated Molecular Characterization of Intraductal Papillary Mucinous Neoplasms: An NCI Cancer Moonshot Precancer Atlas Pilot Project.
Cancer Res Commun
; 3(10): 2062-2073, 2023 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37721516
10.
The breast pre-cancer atlas illustrates the molecular and micro-environmental diversity of ductal carcinoma in situ.
NPJ Breast Cancer
; 8(1): 6, 2022 Jan 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-35027560
11.
Prevalence of cancer susceptibility variants in patients with multiple Lynch syndrome related cancers.
Sci Rep
; 11(1): 14807, 2021 07 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-34285288
12.
Inhibition of mTOR signaling and clinical activity of metformin in oral premalignant lesions.
JCI Insight
; 6(17)2021 09 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-34255745
13.
Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.
BMC Med Genomics
; 13(1): 173, 2020 11 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-33208147
14.
Mitochondrial DNA Mutations are Associated with Ulcerative Colitis Preneoplasia but Tend to be Negatively Selected in Cancer.
Mol Cancer Res
; 17(2): 488-498, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30446624
15.
Ultra-Sensitive TP53 Sequencing for Cancer Detection Reveals Progressive Clonal Selection in Normal Tissue over a Century of Human Lifespan.
Cell Rep
; 28(1): 132-144.e3, 2019 07 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31269435
16.
Targeted deletion of AKAP7 in dentate granule cells impairs spatial discrimination.
Elife
; 52016 12 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27911261