A Low-Power Wireless System for Predicting Early Signs of Sudden Cardiac Arrest Incorporating an Optimized CNN Model Implemented on NVIDIA Jetson.

The survival rate for sudden cardiac arrest (SCA) is low, and patients with long-term risks of SCA are not adequately alerted. Understanding SCA's characteristics will be key to developing preventive strategies. Many lives could be saved if SCA's early onset could be detected or predicted. Monitoring heart signals continuously is essential for diagnosing sporadic cardiac dysfunction. An electrocardiogram (ECG) can be used to continuously monitor heart function without having to go to the hospital. A zeolite-based dry electrode can provide safe on-skin ECG acquisition while the subject is out-of-hospital and facilitate long-term monitoring. To the ECG signal, a low-power 1 µW read-out circuit was designed and implemented in our prior work. However, having long-term ECG monitoring outside the hospital, i.e., high battery life, and low power consumption while transmission and reception of ECG signal are crucial. This paper proposes a prototype with a 10-bit resolution ADC and nRF24L01 transceivers placed 5 m apart. The system uses the 2.4 GHz worldwide ISM frequency band with GFSK modulation to wirelessly transmit digitized ECG bits at 250 kbps data rate to a physician's computer (or similar) for continuous monitoring of ECG signals; the power consumption is only 11.2 mW and 4.62 mW during transmission and reception, respectively, with a low bit error rate of ≤0.1%. Additionally, a subject-wise cross-validated, three-fold, optimized convolutional neural network (CNN) model using the Physionet-SCA dataset was implemented on NVIDIA Jetson to identify the irregular heartbeats yielding an accuracy of 89% with a run time of 5.31 s. Normal beat classification has an F1 score of 0.94 and a ROC score of 0.886. Thus, this paper integrates the ECG acquisition and processing unit with low-power wireless transmission and CNN model to detect irregular heartbeats.

Air Corridors: Concept, Design, Simulation, and Rules of Engagement.

Air corridors are an integral part of the advanced air mobility infrastructure. They are the virtual highways in the sky for the transportation of people and cargo in a controlled airspace at an altitude of around 1000 ft. to 2000 ft. above ground level. These corridors will be utilized by (unmanned) air taxis, which will be deployed in rural and metropolitan regions to carry passengers and freight, as well as air ambulances, which will be deployed to offer first responder services such as 911 emergencies. This paper presents fundamental insights into the design of air corridors with high operational efficiency as well as zero collisions. It begins with the definitions of air cube, skylane or track, intersection, vertiport, gate, and air corridor. Then a multi-layered air corridor model is proposed. Traffic at intersections is analyzed in detail with examples of vehicles turning in different directions. The concept of capacity of an air corridor is introduced along with the nature of distribution of locations of vehicles in the air corridor and collision probability inside the corridor are discussed. Finally, results of traffic flow simulations are presented.

Impact of Leadership and Mobility on Consensus-Building in Sensor Networks.

Introducing leadership and mobility is known to benefit wireless sensor networks in terms of consensus-building and collective decision-making. However, these benefits are neither analytically proven nor quantified in the literature. This paper fills this gap by investigating the mobility dynamics in wireless sensor networks analytically. The results of the analytical investigation are presented as a set of theorems and their proofs. This paper also establishes a natural synergy between the leader-follower model and its bipartite graph representation. It demonstrates the advantages of the leader-follower model for consensus-building over others in terms of improved convergence rate. It presents a strategy for choosing leaders from among the agents participating in the consensus-building process using the well-known graph-coloring solution. Then, it shows how the leader-follower model helps improve the convergence rate of consensus-building. Finally, it shows that the convergence rate of the consensus-building process can be further improved by making the leaders mobile.

Patterns of communication during full-scale emergency/disaster drills.

The motivation for developing, administering, and participating in full-scale disaster drills is multifold. Emergency drills not only test the capacity of emergency systems but also allow organizations to learn as well as improve processes and communication structures before disasters strike. They have been used as a platform to develop and maintain collaborative networks. This article examines the extent to which organizations collaborate with others during emergency/disaster drills. A social network analysis is employed to determine the patterns of communication and interorganizational networks during the planning and implementation of a full-scale emergency exercise. Specifically, we seek to understand the communication lines that stakeholders used to receive updated information, who they reached out to when standard communication channels were down, and what backup systems were in place. The research was conducted in a municipality located in north central Texas. This study was based on field observations and involved 14 face-to-face interviews with experienced public officials and first responders involved in a municipal government emergency drill/exercise. The interviews were administered after the 2017 full-scale emergency drill. Three major findings can be emphasized from this study. First, two types of organizations, namely, city fire departments and a university partaking in the exercise, played central role as a "bridge" between various organizations during the emergency drill. Second, the types of information considered important during the exercise can be categorized as strategic, procedural, and technical information. Finally, several back-up systems including ham radio, cellphones, internet back-up, and satellite were used to maintain communication channels.

Dose prediction with deep learning for prostate cancer radiation therapy: Model adaptation to different treatment planning practices.

PURPOSE: This work aims to study the generalizability of a pre-developed deep learning (DL) dose prediction model for volumetric modulated arc therapy (VMAT) for prostate cancer and to adapt the model, via transfer learning with minimal input data, to three different internal treatment planning styles and one external institution planning style. METHODS: We built the source model with planning data from 108 patients previously treated with VMAT for prostate cancer. For the transfer learning, we selected patient cases planned with three different styles, 14-29 cases per style, in the same institution and 20 cases treated in a different institution to adapt the source model to four target models in total. We compared the dose distributions predicted by the source model and the target models with the corresponding clinical plan dose used for patient treatments and quantified the improvement in the prediction quality for the target models over the source model using the Dice similarity coefficients (DSC) of 0% to 100% isodose volumes and the dose-volume-histogram (DVH) parameters of the planning target volume and the organs-at-risk. RESULTS: The source model accurately predicts dose distributions for plans generated in the same source style, but performs sub-optimally for the three different internal and one external target styles, with the mean DSC ranging between 0.81-0.94 and 0.82-0.91 for the internal and the external styles, respectively. With transfer learning, the target model predictions improved the mean DSC to 0.88-0.95 and 0.92-0.96 for the internal and the external styles, respectively. Target model predictions significantly improved the accuracy of the DVH parameter predictions to within 1.6%. CONCLUSION: We demonstrated the problem of model generalizability for DL-based dose prediction and the feasibility of using transfer learning to solve this problem. With 14-29 cases per style, we successfully adapted the source model into several different practice styles. This indicates a realistic way forward to widespread clinical implementation of DL-based dose prediction.