Detalhe da pesquisa
1.
Selective inhibitors of the PSEN1-gamma-secretase complex.
J Biol Chem
; 299(6): 104794, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37164155
2.
Tubulin-Binding 3,5-Bis(styryl)pyrazoles as Lead Compounds for the Treatment of Castration-Resistant Prostate Cancer.
Mol Pharmacol
; 97(6): 409-422, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32241960
3.
Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells.
J Nat Prod
; 82(7): 1768-1778, 2019 07 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31282672
4.
A Carbocyclic Curcumin Inhibits Proliferation of Gram-Positive Bacteria by Targeting FtsZ.
Biochemistry
; 56(3): 514-524, 2017 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-28002947
5.
Correction to Synthesis of Usnic Acid Derivatives and Evaluation of Their Antiproliferative Activity against Cancer Cells.
J Nat Prod
; 83(2): 563-564, 2020 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32065747
6.
Substrate-targeting gamma-secretase modulators.
Nature
; 453(7197): 925-9, 2008 Jun 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-18548070
7.
Discovery of brain permeable 2-Azabicyclo[2.2.2]octane sulfonamides as a novel class of presenilin-1 selective γ-secretase inhibitors.
Eur J Med Chem
; 260: 115725, 2023 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37657269
8.
(1E,4Z,6E)-5-Hy-droxy-1,7-bis-(2-meth-oxy-phen-yl)-1,4,6-hepta-trien-3-one.
Acta Crystallogr Sect E Struct Rep Online
; 67(Pt 8): o1885, 2011 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22090937
9.
Curcumin cross-links cystic fibrosis transmembrane conductance regulator (CFTR) polypeptides and potentiates CFTR channel activity by distinct mechanisms.
J Biol Chem
; 284(45): 30754-65, 2009 Nov 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19740743
10.
Safe targeting of T cell acute lymphoblastic leukemia by pathology-specific NOTCH inhibition.
Sci Transl Med
; 11(494)2019 05 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-31142678
11.
Remarkable Enhancement in Boron Uptake Within Glioblastoma Cells With Carboranyl-Indole Carboxamides.
Chem Asian J
; 13(21): 3321-3327, 2018 Nov 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30369074
12.
Scaffold of the cyclooxygenase-2 (COX-2) inhibitor carprofen provides Alzheimer gamma-secretase modulators.
J Med Chem
; 49(26): 7588-91, 2006 Dec 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-17181139
13.
MDMA ('Ecstasy'), oxytocin and vasopressin modulate social preference in rats: A role for handling and oxytocin receptors.
Pharmacol Biochem Behav
; 150-151: 115-123, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27725273
14.
Drug development and PET-diagnostics for Alzheimer's disease.
Curr Med Chem
; 12(14): 1677-95, 2005.
Artigo
em Inglês
| MEDLINE | ID: mdl-16022665
15.
WAY 267,464, a non-peptide oxytocin receptor agonist, impairs social recognition memory in rats through a vasopressin 1A receptor antagonist action.
Psychopharmacology (Berl)
; 232(15): 2659-67, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25761839
16.
First Demonstration of Positive Allosteric-like Modulation at the Human Wild Type Translocator Protein (TSPO).
J Med Chem
; 58(21): 8743-9, 2015 Nov 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-26461041
17.
Two new ceramides from the fruit pulp of Acanthopanax senticosus (Rupr. et Maxim) Harms.
Nat Prod Res
; 28(3): 144-9, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24261557
18.
Acute prosocial effects of oxytocin and vasopressin when given alone or in combination with 3,4-methylenedioxymethamphetamine in rats: involvement of the V1A receptor.
Neuropsychopharmacology
; 38(11): 2249-59, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23676791
19.
Hybrid ortho/allosteric ligands for the adenosine A(1) receptor.
J Med Chem
; 53(8): 3028-37, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20345101
20.
Substituted terphenyl compounds as the first class of low molecular weight allosteric inhibitors of the luteinizing hormone receptor.
J Med Chem
; 52(7): 2036-42, 2009 Apr 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-19296599