Detalhe da pesquisa
1.
Modifying the Basicity of the dNTP Leaving Group Modulates Precatalytic Conformational Changes of DNA Polymerase ß.
Biochemistry
; 2024 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38780930
2.
A pre-catalytic non-covalent step governs DNA polymerase ß fidelity.
Nucleic Acids Res
; 47(22): 11839-11849, 2019 12 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31732732
3.
Completing the ß,γ-CXY-dNTP Stereochemical Probe Toolkit: Synthetic Access to the dCTP Diastereomers and 31P and 19F NMR Correlations with Absolute Configurations.
J Org Chem
; 85(22): 14592-14609, 2020 11 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-33125847
4.
Probing DNA Base-Dependent Leaving Group Kinetic Effects on the DNA Polymerase Transition State.
Biochemistry
; 57(26): 3925-3933, 2018 07 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29889506
5.
A Change in the Rate-Determining Step of Polymerization by the K289M DNA Polymerase ß Cancer-Associated Variant.
Biochemistry
; 56(15): 2096-2105, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28326765
6.
DNA Polymerase ß Cancer-Associated Variant I260M Exhibits Nonspecific Selectivity toward the ß-γ Bridging Group of the Incoming dNTP.
Biochemistry
; 56(40): 5449-5456, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28862868
7.
New Chirally Modified Bisphosphonates for Synthesis of Individual Beta,Gamma-CHX-Deoxynucleotide Diastereomers.
Phosphorus Sulfur Silicon Relat Elem
; 194(4-6): 329-330, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-32377060