Detalhe da pesquisa
1.
Impaired Adipogenesis and Dysfunctional Adipose Tissue in Human Hypertrophic Obesity.
Physiol Rev
; 98(4): 1911-1941, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30067159
2.
Lipid droplet-associated kinase STK25 regulates peroxisomal activity and metabolic stress response in steatotic liver.
J Lipid Res
; 61(2): 178-191, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31857389
3.
Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans.
FASEB J
; 33(9): 9974-9989, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31173506
4.
Increased expression of STK25 leads to impaired glucose utilization and insulin sensitivity in mice challenged with a high-fat diet.
FASEB J
; 27(9): 3660-71, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23729594
5.
The impact of cellular senescence in human adipose tissue.
J Cell Commun Signal
; 17(3): 563-573, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37195383
6.
Increased cell senescence in human metabolic disorders.
J Clin Invest
; 133(12)2023 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37317964
7.
Type 2 Diabetes, Independent of Obesity and Age, Is Characterized by Senescent and Dysfunctional Mature Human Adipose Cells.
Diabetes
; 71(11): 2372-2383, 2022 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36006465
8.
ZMAT3 hypomethylation contributes to early senescence of preadipocytes from healthy first-degree relatives of type 2 diabetics.
Aging Cell
; 21(3): e13557, 2022 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35146866
9.
Depletion of protein kinase STK25 ameliorates renal lipotoxicity and protects against diabetic kidney disease.
JCI Insight
; 5(24)2020 12 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33170807
10.
Reduced subcutaneous adipogenesis in human hypertrophic obesity is linked to senescent precursor cells.
Nat Commun
; 10(1): 2757, 2019 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-31227697
11.
Human adipose tissue microvascular endothelial cells secrete PPARγ ligands and regulate adipose tissue lipid uptake.
JCI Insight
; 4(5)2019 03 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30843883
12.
Arthritis suppression by NADPH activation operates through an interferon-beta pathway.
BMC Biol
; 5: 19, 2007 May 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-17490473
13.
Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.
EBioMedicine
; 27: 151-155, 2018 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-29246479
14.
Overexpressing the novel autocrine/endocrine adipokine WISP2 induces hyperplasia of the heart, white and brown adipose tissues and prevents insulin resistance.
Sci Rep
; 7: 43515, 2017 02 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-28240264
15.
Epstein-Barr virus nuclear antigen 5 inhibits pre-mRNA cleavage and polyadenylation.
Nucleic Acids Res
; 30(10): 2131-43, 2002 May 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-12000833
16.
Partial hepatic resistance to IL-6-induced inflammation develops in type 2 diabetic mice, while the anti-inflammatory effect of AMPK is maintained.
Mol Cell Endocrinol
; 393(1-2): 143-51, 2014 Aug 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-24976178
17.
Pharmacological activation of AMPK suppresses inflammatory response evoked by IL-6 signalling in mouse liver and in human hepatocytes.
Mol Cell Endocrinol
; 375(1-2): 68-78, 2013 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23707791
18.
Copy number variation of the gene NCF1 is associated with rheumatoid arthritis.
Antioxid Redox Signal
; 16(1): 71-8, 2012 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21728841
19.
HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes.
Nat Cell Biol
; 12(1): 80-6; sup pp 1-12, 2010 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-20023648
20.
Relationship between AMPK and the transcriptional balance of clock-related genes in skeletal muscle.
Am J Physiol Endocrinol Metab
; 295(5): E1032-7, 2008 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-18728219