Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Author Correction: Hobit- and Blimp-1-driven CD4⁺ tissue-resident memory T cells control chronic intestinal inflammation.

Zundler, Sebastian; Becker, Emily; Spocinska, Marta; Slawik, Monique; Parga-Vidal, Loreto; Stark, Regina; Wiendl, Maximilian; Atreya, Raja; Rath, Timo; Leppkes, Moritz; Hildner, Kai; López-Posadas, Rocío; Lukassen, Sören; Ekici, Arif B; Neufert, Clemens; Atreya, Imke; van Gisbergen, Klaas P J M; Neurath, Markus F.

Nat Immunol ; 20(4): 514, 2019 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-30846879

2.

Hobit- and Blimp-1-driven CD4⁺ tissue-resident memory T cells control chronic intestinal inflammation.

Zundler, Sebastian; Becker, Emily; Spocinska, Marta; Slawik, Monique; Parga-Vidal, Loreto; Stark, Regina; Wiendl, Maximilian; Atreya, Raja; Rath, Timo; Leppkes, Moritz; Hildner, Kai; López-Posadas, Rocío; Lukassen, Sören; Ekici, Arif B; Neufert, Clemens; Atreya, Imke; van Gisbergen, Klaas P J M; Neurath, Markus F.

Nat Immunol ; 20(3): 288-300, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30692620

3.

p21 Prevents the Exhaustion of CD4⁺ T Cells Within the Antitumor Immune Response Against Colorectal Cancer.

Thoma, Oana-Maria; Naschberger, Elisabeth; Kubánková, Markéta; Larafa, Imen; Kramer, Viktoria; Menchicchi, Bianca; Merkel, Susanne; Britzen-Laurent, Nathalie; Jefremow, André; Grützmann, Robert; Koop, Kristina; Neufert, Clemens; Atreya, Raja; Guck, Jochen; Stürzl, Michael; Neurath, Markus F; Waldner, Maximilian J.

Gastroenterology ; 166(2): 284-297.e11, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-37734420

4.

Neutrophils prevent rectal bleeding in ulcerative colitis by peptidyl-arginine deiminase-4-dependent immunothrombosis.

Leppkes, Moritz; Lindemann, Aylin; Gößwein, Stefanie; Paulus, Susanne; Roth, Dominik; Hartung, Anne; Liebing, Eva; Zundler, Sebastian; Gonzalez-Acera, Miguel; Patankar, Jay V; Mascia, Fabrizio; Scheibe, Kristina; Hoffmann, Markus; Uderhardt, Stefan; Schauer, Christine; Foersch, Sebastian; Neufert, Clemens; Vieth, Michael; Schett, Georg; Atreya, Raja; Kühl, Anja A; Bleich, Andre; Becker, Christoph; Herrmann, Martin; Neurath, Markus F.

Gut ; 71(12): 2414-2429, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-34862250

5.

A Possible Distinct Molecular Subtype (Quintuple-Wildtype) of Metastatic Colorectal Cancer in First-Line Anti-EGFR Therapy with Cetuximab Plus FOLFIRI - Palliative Precision Therapy and a Multidisciplinary Treatment Approach: Interim Analysis of the IVOPAK II Trial with Early Results.

Wein, Axel; Stoehr, Robert; Kersting, Stephan; Siebler, Jürgen; Merkel, Susanne; Busse, Dagmar; Wolff, Kerstin; Ostermeier, Nicola; Neufert, Clemens; Vitali, Francesco; Eckstein, Markus; Roth, Jan-Peter; Anhut, Peter; Schreiner, Waldemar; Uder, Michael; Hartmann, Arndt; Neurath, Markus F; Grützmann, Robert.

Oncology ; 100(1): 1-11, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-34670215

6.

The outcome of patients with inflammatory bowel disease-associated colorectal cancer is not worse than that of patients with sporadic colorectal cancer-a matched-pair analysis of survival.

Vitali, Francesco; Wein, Axel; Rath, Timo; Eckstein, Markus; Neufert, Clemens; Siebler, Jürgen; Atreya, Raja; Hartmann, Arndt; Hohenberger, Werner; Weber, Klaus; Neurath, Markus Friedrich; Grützmann, Robert; Merkel, Susanne.

Int J Colorectal Dis ; 37(2): 381-391, 2022 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-34865179

7.

Dynamic Imaging of IEL-IEC Co-Cultures Allows for Quantification of CD103-Dependent T Cell Migration.

Enderle, Karin; Dinkel, Martin; Spath, Eva-Maria; Schmid, Benjamin; Zundler, Sebastian; Tripal, Philipp; Neurath, Markus F; Hildner, Kai; Neufert, Clemens.

Int J Mol Sci ; 22(10)2021 May 13.

Artigo em Inglês | MEDLINE | ID: mdl-34067987

8.

Non-classical monocyte homing to the gut via α4ß7 integrin mediates macrophage-dependent intestinal wound healing.

Schleier, Lena; Wiendl, Maximilian; Heidbreder, Karin; Binder, Marie-Theres; Atreya, Raja; Rath, Timo; Becker, Emily; Schulz-Kuhnt, Anja; Stahl, Annette; Schulze, Lisa Lou; Ullrich, Karen; Merz, Simon F; Bornemann, Lea; Gunzer, Matthias; Watson, Alastair J M; Neufert, Clemens; Atreya, Imke; Neurath, Markus F; Zundler, Sebastian.

Gut ; 69(2): 252-263, 2020 02.

Artigo em Inglês | MEDLINE | ID: mdl-31092589

9.

STAT3 activation through IL-6/IL-11 in cancer-associated fibroblasts promotes colorectal tumour development and correlates with poor prognosis.

Heichler, Christina; Scheibe, Kristina; Schmied, Anabel; Geppert, Carol I; Schmid, Benjamin; Wirtz, Stefan; Thoma, Oana-Maria; Kramer, Viktoria; Waldner, Maximilian J; Büttner, Christian; Farin, Henner F; Pesic, Marina; Knieling, Ferdinand; Merkel, Susanne; Grüneboom, Anika; Gunzer, Matthias; Grützmann, Robert; Rose-John, Stefan; Koralov, Sergei B; Kollias, George; Vieth, Michael; Hartmann, Arndt; Greten, Florian R; Neurath, Markus F; Neufert, Clemens.

Gut ; 69(7): 1269-1282, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-31685519

10.

Inhibiting PGGT1B Disrupts Function of RHOA, Resulting in T-cell Expression of Integrin α4ß7 and Development of Colitis in Mice.

López-Posadas, Rocío; Fastancz, Petra; Martínez-Sánchez, Luz Del Carmen; Panteleev-Ivlev, Julia; Thonn, Veronika; Kisseleva, Tatyana; Becker, Lukas S; Schulz-Kuhnt, Anja; Zundler, Sebastian; Wirtz, Stefan; Atreya, Raja; Carlé, Birgitta; Friedrich, Oliver; Schürmann, Sebastian; Waldner, Maximilian J; Neufert, Clemens; Brakebusch, Cord H; Bergö, Martin O; Neurath, Markus F; Atreya, Imke.

Gastroenterology ; 157(5): 1293-1309, 2019 11.

Artigo em Inglês | MEDLINE | ID: mdl-31302143

11.

Inhibiting Interleukin 36 Receptor Signaling Reduces Fibrosis in Mice With Chronic Intestinal Inflammation.

Scheibe, Kristina; Kersten, Christina; Schmied, Anabel; Vieth, Michael; Primbs, Tatjana; Carlé, Birgitta; Knieling, Ferdinand; Claussen, Jing; Klimowicz, Alexander C; Zheng, Jie; Baum, Patrick; Meyer, Sebastian; Schürmann, Sebastian; Friedrich, Oliver; Waldner, Maximilian J; Rath, Timo; Wirtz, Stefan; Kollias, George; Ekici, Arif B; Atreya, Raja; Raymond, Ernest L; Mbow, M Lamine; Neurath, Markus F; Neufert, Clemens.

Gastroenterology ; 156(4): 1082-1097.e11, 2019 03.

Artigo em Inglês | MEDLINE | ID: mdl-30452921

12.

Challenging a Preconception: Optoacoustic Spectrum Differs from the Optical Absorption Spectrum of Proteins and Dyes for Molecular Imaging.

Fuenzalida Werner, Juan Pablo; Huang, Yuanhui; Mishra, Kanuj; Janowski, Robert; Vetschera, Paul; Heichler, Christina; Chmyrov, Andriy; Neufert, Clemens; Niessing, Dierk; Ntziachristos, Vasilis; Stiel, Andre C.

Anal Chem ; 92(15): 10717-10724, 2020 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-32640156

13.

Expansion of IL-23 receptor bearing TNFR2+ T cells is associated with molecular resistance to anti-TNF therapy in Crohn's disease.

Schmitt, Heike; Billmeier, Ulrike; Dieterich, Walburga; Rath, Timo; Sonnewald, Sophia; Reid, Stephen; Hirschmann, Simon; Hildner, Kai; Waldner, Maximilian J; Mudter, Jonas; Hartmann, Arndt; Grützmann, Robert; Neufert, Clemens; Münster, Tino; Neurath, Markus F; Atreya, Raja.

Gut ; 68(5): 814-828, 2019 05.

Artigo em Inglês | MEDLINE | ID: mdl-29848778

14.

Transmural intestinal fibrosis in men and mice.

Neufert, Clemens.

Gut ; 71(7): 1242-1244, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-34725200

15.

Blockade of αEß7 integrin suppresses accumulation of CD8⁺ and Th9 lymphocytes from patients with IBD in the inflamed gut in vivo.

Zundler, Sebastian; Schillinger, Daniela; Fischer, Anika; Atreya, Raja; López-Posadas, Rocío; Watson, Alastair; Neufert, Clemens; Atreya, Imke; Neurath, Markus F.

Gut ; 66(11): 1936-1948, 2017 11.

Artigo em Inglês | MEDLINE | ID: mdl-27543429

16.

IL-36R signalling activates intestinal epithelial cells and fibroblasts and promotes mucosal healing in vivo.

Scheibe, Kristina; Backert, Ingo; Wirtz, Stefan; Hueber, Axel; Schett, Georg; Vieth, Michael; Probst, Hans Christian; Bopp, Tobias; Neurath, Markus F; Neufert, Clemens.

Gut ; 66(5): 823-838, 2017 05.

Artigo em Inglês | MEDLINE | ID: mdl-26783184

17.

Differential effects of α4ß7 and GPR15 on homing of effector and regulatory T cells from patients with UC to the inflamed gut in vivo.

Fischer, Anika; Zundler, Sebastian; Atreya, Raja; Rath, Timo; Voskens, Caroline; Hirschmann, Simon; López-Posadas, Rocío; Watson, Alastair; Becker, Christoph; Schuler, Gerold; Neufert, Clemens; Atreya, Imke; Neurath, Markus F.

Gut ; 65(10): 1642-64, 2016 10.

Artigo em Inglês | MEDLINE | ID: mdl-26209553

18.

Label-Free In Vivo Histopathology of Experimental Colitis via 3-Channel Multiphoton Endomicroscopy.

Kreiß, Lucas; Thoma, Oana-Maria; Dilipkumar, Ashwathama; Carlé, Birgitta; Longequeue, Pascal; Kunert, Timo; Rath, Timo; Hildner, Kai; Neufert, Clemens; Vieth, Michael; Neurath, Markus F; Friedrich, Oliver; Schürmann, Sebastian; Waldner, Maximilian J.

Gastroenterology ; 159(3): 832-834, 2020 09.

Artigo em Inglês | MEDLINE | ID: mdl-32544392

19.

STAT3 activation in Th17 and Th22 cells controls IL-22-mediated epithelial host defense during infectious colitis.

Backert, Ingo; Koralov, Sergei B; Wirtz, Stefan; Kitowski, Vera; Billmeier, Ulrike; Martini, Eva; Hofmann, Katharina; Hildner, Kai; Wittkopf, Nadine; Brecht, Katrin; Waldner, Maximilian; Rajewsky, Klaus; Neurath, Markus F; Becker, Christoph; Neufert, Clemens.

J Immunol ; 193(7): 3779-91, 2014 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-25187663

20.

Multispectral Optoacoustic Tomography for Assessment of Crohn's Disease Activity.

Knieling, Ferdinand; Neufert, Clemens; Hartmann, Arndt; Claussen, Jing; Urich, Alexander; Egger, Cornelia; Vetter, Marcel; Fischer, Sarah; Pfeifer, Lukas; Hagel, Alexander; Kielisch, Christian; Görtz, Rüdiger S; Wildner, Dane; Engel, Matthias; Röther, Jens; Uter, Wolfgang; Siebler, Jürgen; Atreya, Raja; Rascher, Wolfgang; Strobel, Deike; Neurath, Markus F; Waldner, Maximilian J.

N Engl J Med ; 376(13): 1292-1294, 2017 03 30.

Artigo em Inglês | MEDLINE | ID: mdl-28355498

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