Detalhe da pesquisa
1.
Author Correction: LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Nature
; 575(7783): E5, 2019 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-31695192
2.
The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival.
Nature
; 546(7658): 426-430, 2017 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28607489
3.
Proteomic analysis of pRb loss highlights a signature of decreased mitochondrial oxidative phosphorylation.
Genes Dev
; 29(17): 1875-89, 2015 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-26314710
4.
LKB1 loss links serine metabolism to DNA methylation and tumorigenesis.
Nature
; 539(7629): 390-395, 2016 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27799657
5.
Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism.
Nature
; 524(7565): 361-5, 2015 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-26168401
6.
Loss of RBF1 changes glutamine catabolism.
Genes Dev
; 27(2): 182-96, 2013 Jan 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23322302
7.
Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.
Proc Natl Acad Sci U S A
; 113(7): 1778-83, 2016 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-26831078
8.
Cooperation between dE2F1 and Yki/Sd defines a distinct transcriptional program necessary to bypass cell cycle exit.
Genes Dev
; 25(4): 323-35, 2011 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-21325133
9.
Notch-dependent expression of the archipelago ubiquitin ligase subunit in the Drosophila eye.
Development
; 138(2): 251-60, 2011 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-21148181
10.
Tuberous sclerosis complex 1 regulates dE2F1 expression during development and cooperates with RBF1 to control proliferation and survival.
PLoS Genet
; 6(8): e1001071, 2010 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20808898
11.
Combined inactivation of pRB and hippo pathways induces dedifferentiation in the Drosophila retina.
PLoS Genet
; 6(4): e1000918, 2010 Apr 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-20421993
12.
Context-dependent requirement for dE2F during oncogenic proliferation.
PLoS Genet
; 4(10): e1000205, 2008 Oct 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-18833298
13.
Discovery of M-1121 as an Orally Active Covalent Inhibitor of Menin-MLL Interaction Capable of Achieving Complete and Long-Lasting Tumor Regression.
J Med Chem
; 64(14): 10333-10349, 2021 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-34196551
14.
It's all in the timing: too much E2F is a bad thing.
PLoS Genet
; 8(8): e1002909, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-22916039
15.
Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy.
Cancer Metab
; 8: 1, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-31908776
16.
E2F1 mediates sustained lipogenesis and contributes to hepatic steatosis.
J Clin Invest
; 126(1): 137-50, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26619117
17.
CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers.
Cancer Res
; 74(14): 3947-58, 2014 Jul 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-24986516
18.
The multiple connections between pRB and cell metabolism.
Curr Opin Cell Biol
; 25(6): 735-40, 2013 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-23916769
19.
Drosophila GAGA factor is required for full activation of the dE2f1-Yki/Sd transcriptional program.
Cell Cycle
; 11(22): 4191-202, 2012 Nov 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23070566
20.
Mosaic genetic screen for suppressors of the de2f1 mutant phenotype in Drosophila.
Genetics
; 183(1): 79-92, 2009 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-19546319