Detalhe da pesquisa
1.
Pathogenesis of chemically induced nasal cavity tumors in rodents: contribution to adverse outcome pathway.
J Toxicol Pathol
; 37(1): 11-27, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38283373
2.
A comprehensive review of mechanistic insights into formaldehyde-induced nasal cavity carcinogenicity.
Regul Toxicol Pharmacol
; 123: 104937, 2021 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-33905780
3.
Chemical carcinogen safety testing: OECD expert group international consensus on the development of an integrated approach for the testing and assessment of chemical non-genotoxic carcinogens.
Arch Toxicol
; 94(8): 2899-2923, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32594184
4.
Immunohistochemistry of γ-H2AX as a method of early detection of urinary bladder carcinogenicity in mice.
J Appl Toxicol
; 39(6): 868-876, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30701581
5.
Current state of therapeutic development for rare cancers in Japan, and proposals for improvement.
Cancer Sci
; 109(5): 1731-1737, 2018 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-29878624
6.
International regulatory requirements for skin sensitization testing.
Regul Toxicol Pharmacol
; 95: 52-65, 2018 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518484
7.
Role of oxidative stress in the chemical structure-related genotoxicity of nitrofurantoin in Nrf2-deficient gpt delta mice.
J Toxicol Pathol
; 31(3): 169-178, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093786
8.
Mechanisms of oxidative stress-induced in vivo mutagenicity by potassium bromate and nitrofurantoin.
J Toxicol Pathol
; 31(3): 179-188, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-30093787
9.
Non-neoplastic lesions found only in the two-year bioassays but not in shorter toxicity studies of rats.
Regul Toxicol Pharmacol
; 86: 199-204, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28288808
10.
Horseradish extract promotes urinary bladder carcinogenesis when administered to F344 rats in drinking water.
J Appl Toxicol
; 37(7): 853-862, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28165151
11.
Lack of genotoxic mechanisms in early-stage furan-induced hepatocellular tumorigenesis in gpt delta rats.
J Appl Toxicol
; 37(2): 142-149, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-27143483
12.
Lack of in vivo mutagenicity of 1,2-dichloropropane and dichloromethane in the livers of gpt delta rats administered singly or in combination.
J Appl Toxicol
; 37(6): 683-691, 2017 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27896817
13.
Toxic effects of 4-methylthio-3-butenyl isothiocyanate (Raphasatin) in the rat urinary bladder without genotoxicity.
J Appl Toxicol
; 37(4): 485-494, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-27633481
14.
Anti-Inflammatory Effects of Capsaicin and Piperine on Helicobacter pylori-Induced Chronic Gastritis in Mongolian Gerbils.
Helicobacter
; 21(2): 131-42, 2016 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-26140520
15.
Perspectives on the elimination of animal assays in the assessment of carcinogenicity.
Regul Toxicol Pharmacol
; 126: 105031, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34437954
16.
International Harmonization and Cooperation in the Validation of Alternative Methods.
Adv Exp Med Biol
; 856: 343-386, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-27671730
17.
4-Methylthio-3-butenyl isothiocyanate (raphasatin) exerts chemopreventive effects against esophageal carcinogenesis in rats.
J Toxicol Pathol
; 29(4): 237-246, 2016 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-27821908
18.
Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats.
Cancer Sci
; 106(5): 529-41, 2015 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-25683344
19.
Acrylamide induces specific DNA adduct formation and gene mutations in a carcinogenic target site, the mouse lung.
Mutagenesis
; 30(2): 227-35, 2015 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-25392148
20.
Orally administered glycidol and its fatty acid esters as well as 3-MCPD fatty acid esters are metabolized to 3-MCPD in the F344 rat.
Regul Toxicol Pharmacol
; 73(3): 726-31, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26520183