Detalhe da pesquisa
1.
(2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in Escherichia coli PpiB: Protein Production, 19F NMR, and Ligand Sensing Enhanced by the γ-Gauche Effect.
Biochemistry
; 63(11): 1376-1387, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38753308
2.
Conformational Preferences of the Non-Canonical Amino Acids (2S,4S)-5-Fluoroleucine, (2S,4R)-5-Fluoroleucine, and 5,5'-Difluoroleucine in a Protein.
Biochemistry
; 63(11): 1388-1394, 2024 Jun 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38742763
3.
Biocompatible Synthesis of Macrocyclic Thiazol(in)e Peptides.
Chemistry
; : e202401716, 2024 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-38708622
4.
Exploiting Hydrophobic Amino Acid Scanning to Develop Cyclic Peptide Inhibitors of the SARS-CoV-2 Main Protease with Antiviral Activity.
Chemistry
; : e202401606, 2024 May 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38801240
5.
Paramagnetic Chemical Probes for Studying Biological Macromolecules.
Chem Rev
; 122(10): 9571-9642, 2022 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35084831
6.
Exploring biocompatible chemistry to create stapled and photoswitchable variants of the antimicrobial peptide aurein 1.2.
J Pept Sci
; 30(4): e3551, 2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-37926859
7.
Cell-Penetrating Peptide-Bismuth Bicycles.
Angew Chem Int Ed Engl
; 63(10): e202318615, 2024 Mar 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38126926
8.
Predicting Antiviral Resistance Mutations in SARS-CoV-2 Main Protease with Computational and Experimental Screening.
Biochemistry
; 61(22): 2495-2505, 2022 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-36326185
9.
SARS-CoV-2 Papain-Like Protease: Structure, Function and Inhibition.
Chembiochem
; 23(19): e202200327, 2022 10 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35993805
10.
Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir.
Bioorg Med Chem Lett
; 62: 128629, 2022 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35182772
11.
Peptide-Bismuth Bicycles: In Situ Access to Stable Constrained Peptides with Superior Bioactivity.
Angew Chem Int Ed Engl
; 61(4): e202113857, 2022 01 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-34825756
12.
Biocompatible and Selective Generation of Bicyclic Peptides.
Angew Chem Int Ed Engl
; 61(43): e202208400, 2022 10 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35852030
13.
Genetic Encoding of Cyanopyridylalanine for In-Cell Protein Macrocyclization by the Nitrile-Aminothiol Click Reaction.
Angew Chem Int Ed Engl
; 61(13): e202114154, 2022 03 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35102680
14.
Challenges of short substrate analogues as SARS-CoV-2 main protease inhibitors.
Bioorg Med Chem Lett
; 50: 128333, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34418570
15.
The SARS-CoV-2 main protease as drug target.
Bioorg Med Chem Lett
; 30(17): 127377, 2020 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32738988
16.
Inhibitors of the Zika virus protease NS2B-NS3.
Bioorg Med Chem Lett
; 30(5): 126965, 2020 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31980339
17.
Trimethylsilyl tag for probing protein-ligand interactions by NMR.
J Biomol NMR
; 70(4): 211-218, 2018 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29564580
18.
Small neutral Gd(iii) tags for distance measurements in proteins by double electron-electron resonance experiments.
Phys Chem Chem Phys
; 20(36): 23535-23545, 2018 Sep 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-30183028
19.
Strategies Towards Protease Inhibitors for Emerging Flaviviruses.
Adv Exp Med Biol
; 1062: 175-186, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29845533
20.
Sensitive NMR Approach for Determining the Binding Mode of Tightly Binding Ligand Molecules to Protein Targets.
J Am Chem Soc
; 138(13): 4539-46, 2016 Apr 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26974502