Detalhe da pesquisa
1.
Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc Natl Acad Sci U S A
; 111(46): 16274-9, 2014 Nov 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-25368144
2.
New tools provide a second look at HDV ribozyme structure, dynamics and cleavage.
Nucleic Acids Res
; 42(20): 12833-46, 2014 Nov 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25326328
3.
Synergy of streptogramin antibiotics occurs independently of their effects on translation.
Antimicrob Agents Chemother
; 58(9): 5269-79, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24957822
4.
The importance of helix P1 stability for structural pre-organization and ligand binding affinity of the adenine riboswitch aptamer domain.
RNA Biol
; 11(5): 655-6, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24921630
5.
Cyanotriazoles are selective topoisomerase II poisons that rapidly cure trypanosome infections.
Science
; 380(6652): 1349-1356, 2023 06 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-37384702
6.
Dissecting the influence of Mg2+ on 3D architecture and ligand-binding of the guanine-sensing riboswitch aptamer domain.
Nucleic Acids Res
; 38(12): 4143-53, 2010 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-20200045
7.
Discovery and Optimization of DNA Gyrase and Topoisomerase IV Inhibitors with Potent Activity against Fluoroquinolone-Resistant Gram-Positive Bacteria.
J Med Chem
; 64(9): 6329-6357, 2021 05 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-33929852
8.
Topoisomerase Inhibitors Addressing Fluoroquinolone Resistance in Gram-Negative Bacteria.
J Med Chem
; 63(14): 7773-7816, 2020 07 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-32634310
9.
Time-resolved NMR spectroscopy: ligand-induced refolding of riboswitches.
Methods Mol Biol
; 540: 161-71, 2009.
Artigo
em Inglês
| MEDLINE | ID: mdl-19381559
10.
Metal-ion binding and metal-ion induced folding of the adenine-sensing riboswitch aptamer domain.
Nucleic Acids Res
; 35(15): 5262-73, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17686787
11.
Interplay of 'induced fit' and preorganization in the ligand induced folding of the aptamer domain of the guanine binding riboswitch.
Nucleic Acids Res
; 35(2): 572-83, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17175531
12.
Structures of RNA switches: insight into molecular recognition and tertiary structure.
Angew Chem Int Ed Engl
; 46(8): 1212-9, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17226886
13.
Pausing guides RNA folding to populate transiently stable RNA structures for riboswitch-based transcription regulation.
Elife
; 62017 05 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28541183
14.
High-resolution structure of the Escherichia coli ribosome.
Nat Struct Mol Biol
; 22(4): 336-41, 2015 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-25775265
15.
Cas1-Cas2 complex formation mediates spacer acquisition during CRISPR-Cas adaptive immunity.
Nat Struct Mol Biol
; 21(6): 528-34, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24793649
16.
Structural basis for protein synthesis: snapshots of the ribosome in motion.
Curr Opin Struct Biol
; 22(6): 743-9, 2012 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-22871550
17.
Structures of the bacterial ribosome in classical and hybrid states of tRNA binding.
Science
; 332(6032): 981-4, 2011 May 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-21596992
18.
Time-resolved NMR methods resolving ligand-induced RNA folding at atomic resolution.
Proc Natl Acad Sci U S A
; 104(40): 15699-704, 2007 Oct 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-17895388
19.
Phosphate-group recognition by the aptamer domain of the thiamine pyrophosphate sensing riboswitch.
Chembiochem
; 7(9): 1451-6, 2006 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-16871614
20.
An intermolecular base triple as the basis of ligand specificity and affinity in the guanine- and adenine-sensing riboswitch RNAs.
Proc Natl Acad Sci U S A
; 102(5): 1372-7, 2005 Feb 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-15665103