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1.
AIDS Res Hum Retroviruses ; 18(15): 1145-9, 2002 Oct 10.
Artigo em Inglês | MEDLINE | ID: mdl-12402952

RESUMO

It has been reported that subtypes A throughout H of HIV-1 are circulating in the former Soviet Union. In this sequence note, we analyzed the genetic prevalence of HIV-1 among injecting drug users (IDUs) in Ukraine. The subjects studied included two individuals from Kiev and six individuals from Simferopol', the latter located in the Crimean Peninsula. We found that one of eight IDUs was infected with a CRF03 gagA/envB recombinant HIV-1 and was from Simferopol', whereas the others were infected with HIV-1 subtype A. There combinant was closely related to other A/B recombinants reported previously, and had silent mutations Inthe V3 region, the same as other envB strains of HIV-1 circulating among mDUs in the former Soviet Union. The data supported reports that the Russian AIB recombinant HIV-1 was probably from Ukraine. This is the first report of a CRF03 gagA/envB recombinant HIV-1 found in Ukraine.


Assuntos
Infecções por HIV/epidemiologia , HIV-1/classificação , HIV-1/genética , Recombinação Genética , Abuso de Substâncias por Via Intravenosa/complicações , Sequência de Aminoácidos , Sequência de Bases , Feminino , Proteína gp120 do Envelope de HIV/genética , Infecções por HIV/virologia , Humanos , Masculino , Dados de Sequência Molecular , Fragmentos de Peptídeos/genética , Análise de Sequência de DNA , Ucrânia/epidemiologia
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