Detalhe da pesquisa
1.
Reversibility of peripheral blood leukocyte phenotypic and functional changes after exposure to and withdrawal from tofacitinib, a Janus kinase inhibitor, in healthy volunteers.
Clin Immunol
; 191: 10-20, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29518577
2.
The novel combination of theophylline and bambuterol as a potential treatment of hypoxemia in humans.
Can J Physiol Pharmacol
; 95(9): 1009-1018, 2017 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-28467859
3.
A randomized trial of the safety, pharmacokinetics and pharmacodynamics of edoxaban, an oral factor Xa inhibitor, following a switch from warfarin.
Br J Clin Pharmacol
; 75(4): 966-78, 2013 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22924409
4.
Use of PER977 to reverse the anticoagulant effect of edoxaban.
N Engl J Med
; 371(22): 2141-2, 2014 Nov 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-25371966
5.
Pharmacokinetics of the direct factor Xa inhibitor edoxaban and digoxin administered alone and in combination.
J Cardiovasc Pharmacol
; 60(4): 335-41, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23064240
6.
Low Plasma Gelsolin Concentrations in Chronic Granulomatous Disease.
Inflammation
; 44(1): 270-277, 2021 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-32886268
7.
First-in-Human Studies of MW01-6-189WH, a Brain-Penetrant, Antineuroinflammatory Small-Molecule Drug Candidate: Phase 1 Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Studies in Healthy Adult Volunteers.
Clin Pharmacol Drug Dev
; 10(2): 131-143, 2021 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-32255549
8.
Controlled phase III clinical trial of diclofenac potassium liquid-filled soft gelatin capsule for treatment of postoperative dental pain.
J Oral Maxillofac Surg
; 68(11): 2735-42, 2010 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-20869152
9.
A Phase 1 Randomized Study of Single Intravenous Infusions of the Novel Nitroxyl Donor BMS-986231 in Healthy Volunteers.
J Clin Pharmacol
; 59(5): 717-730, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30703258
10.
Pharmacokinetics and pharmacodynamics of cinacalcet in hepatic impairment : phase I, open-label, parallel-group, single-dose, single-centre study.
Clin Drug Investig
; 28(10): 635-43, 2008.
Artigo
em Inglês
| MEDLINE | ID: mdl-18783302
11.
Safety and Ergogenic Properties of Combined Aminophylline and Ambrisentan in Hypoxia.
Clin Pharmacol Ther
; 103(5): 888-898, 2018 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-28857147
12.
Pharmacokinetics and safety of ebastine in healthy subjects and patients with renal impairment.
Clin Pharmacokinet
; 46(6): 525-34, 2007.
Artigo
em Inglês
| MEDLINE | ID: mdl-17518511
13.
Single-dose ciraparantag safely and completely reverses anticoagulant effects of edoxaban.
Thromb Haemost
; 117(2): 238-245, 2017 01 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-27853809
14.
A Time of Optimism: Targeted Immunotherapeutics as the Long-Awaited Armamentaria Against the Scourge of Human Diseases.
Ther Innov Regul Sci
; 54(2): 444-446, 2020 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-32072584
15.
Intraarterial Microdosing: A Novel Drug Development Approach, Proof-of-Concept PET Study in Rats.
J Nucl Med
; 56(11): 1793-9, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26315828
16.
Pharmacokinetics and safety of ebastine in patients with impaired hepatic function compared with healthy volunteers: a phase I open-label study.
Clin Pharmacokinet
; 43(2): 121-9, 2004.
Artigo
em Inglês
| MEDLINE | ID: mdl-14748620
17.
Pharmacokinetics, pharmacodynamics, and safety of cinacalcet hydrochloride in hemodialysis patients at doses up to 200 mg once daily.
Am J Kidney Dis
; 44(6): 1070-6, 2004 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-15558528
18.
Comparative efficacy and safety of nisoldipine extended-release (ER) and amlodipine (CESNA-III study) in African American patients with hypertension.
Am J Hypertens
; 16(9 Pt 1): 739-45, 2003 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-12944032
19.
Parecoxib sodium, an injectable COX-2-specific inhibitor, does not affect unfractionated heparin-regulated blood coagulation parameters.
J Clin Pharmacol
; 44(5): 474-80, 2004 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-15102867
20.
Assessing acute systemic effects of an inhaled drug with serial echocardiography: a placebo-controlled comparison of inhaled and intravenous dihydroergotamine.
Drug Des Devel Ther
; 7: 619-25, 2013.
Artigo
em Inglês
| MEDLINE | ID: mdl-23926420