Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Impact of Anti-HER2 Therapy Alone and With Weekly Paclitaxel on the Ovarian Reserve of Young Women With HER2-Positive Breast Cancer.

Lambertini, Matteo; Ceppi, Marcello; Anderson, Richard A; Cameron, David A; Bruzzone, Marco; Franzoi, Maria Alice; Massarotti, Claudia; El-Abed, Sarra; Wang, Yingbo; Lecocq, Christophe; Nuciforo, Paolo; Rolyance, Rebecca; Pusztai, Lajos; Sohn, Joohyuk; Latocca, Maria Maddalena; Arecco, Luca; Pistilli, Barbara; Ruddy, Kathryn J; Ballestrero, Alberto; Del Mastro, Lucia; Peccatori, Fedro A; Partridge, Ann H; Saura, Cristina; Untch, Michael; Piccart, Martine; Di Cosimo, Serena; de Azambuja, Evandro; Demeestere, Isabelle.

J Natl Compr Canc Netw ; 21(1): 33-41.e16, 2023 01.

Artigo em Inglês | MEDLINE | ID: mdl-36634607

2.

Diffusion MRI signal cumulants and hepatocyte microstructure at fixed diffusion time: Insights from simulations, 9.4T imaging, and histology.

Grussu, Francesco; Bernatowicz, Kinga; Casanova-Salas, Irene; Castro, Natalia; Nuciforo, Paolo; Mateo, Joaquin; Barba, Ignasi; Perez-Lopez, Raquel.

Magn Reson Med ; 88(1): 365-379, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35181943

3.

A Comprehensive Biomarker Analysis of Microsatellite Unstable/Mismatch Repair Deficient Colorectal Cancer Cohort Treated with Immunotherapy.

Élez, Elena; Mulet-Margalef, Núria; Sanso, Miriam; Ruiz-Pace, Fiorella; Mancuso, Francesco M; Comas, Raquel; Ros, Javier; Argilés, Guillem; Martini, Giulia; Sanz-Garcia, Enrique; Baraibar, Iosune; Salvà, Francesc; Noguerido, Alba; Cuadra-Urteaga, Jose Luis; Fasani, Roberta; Garcia, Ariadna; Jimenez, Jose; Aguilar, Susana; Landolfi, Stefania; Hernández-Losa, Javier; Braña, Irene; Nuciforo, Paolo; Dienstmann, Rodrigo; Tabernero, Josep; Salazar, Ramon; Vivancos, Ana.

Int J Mol Sci ; 24(1)2022 Dec 21.

Artigo em Inglês | MEDLINE | ID: mdl-36613564

4.

Genetic evolution to tyrosine kinase inhibitory therapy in patients with EGFR-mutated non-small-cell lung cancer.

Martinez-Marti, Alex; Felip, Enriqueta; Mancuso, Francesco Mattia; Caratú, Ginevra; Matito, Judit; Nuciforo, Paolo; Sansano, Irene; Diaz-Mejia, Nely; Cedrés, Susana; Callejo, Ana; Iranzo, Patricia; Pardo, Nuria; Miquel, Josep Maria; Navarro, Alejandro; Vivancos, Ana; Sansó, Miriam.

Br J Cancer ; 125(11): 1561-1569, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34599295

5.

PI3K activation promotes resistance to eribulin in HER2-negative breast cancer.

Gris-Oliver, Albert; Ibrahim, Yasir H; Rivas, Martín A; García-García, Celina; Sánchez-Guixé, Mònica; Ruiz-Pace, Fiorella; Viaplana, Cristina; Pérez-García, José M; Llombart-Cussac, Antonio; Grueso, Judit; Parés, Mireia; Guzmán, Marta; Rodríguez, Olga; Anton, Pilar; Cozar, Patricia; Calvo, Maria Teresa; Bruna, Alejandra; Arribas, Joaquín; Caldas, Carlos; Dienstmann, Rodrigo; Nuciforo, Paolo; Oliveira, Mafalda; Cortés, Javier; Serra, Violeta.

Br J Cancer ; 124(9): 1581-1591, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33723394

6.

A CT-based Radiomics Signature Is Associated with Response to Immune Checkpoint Inhibitors in Advanced Solid Tumors.

Ligero, Marta; Garcia-Ruiz, Alonso; Viaplana, Cristina; Villacampa, Guillermo; Raciti, Maria V; Landa, Jaid; Matos, Ignacio; Martin-Liberal, Juan; Ochoa-de-Olza, Maria; Hierro, Cinta; Mateo, Joaquin; Gonzalez, Macarena; Morales-Barrera, Rafael; Suarez, Cristina; Rodon, Jordi; Elez, Elena; Braña, Irene; Muñoz-Couselo, Eva; Oaknin, Ana; Fasani, Roberta; Nuciforo, Paolo; Gil, Debora; Rubio-Perez, Carlota; Seoane, Joan; Felip, Enriqueta; Escobar, Manuel; Tabernero, Josep; Carles, Joan; Dienstmann, Rodrigo; Garralda, Elena; Perez-Lopez, Raquel.

Radiology ; 299(1): 109-119, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33497314

7.

Tumor-Associated Microbiome: Where Do We Stand?

Oliva, Marc; Mulet-Margalef, Nuria; Ochoa-De-Olza, Maria; Napoli, Stefania; Mas, Joan; Laquente, Berta; Alemany, Laia; Duell, Eric J; Nuciforo, Paolo; Moreno, Victor.

Int J Mol Sci ; 22(3)2021 Feb 01.

Artigo em Inglês | MEDLINE | ID: mdl-33535583

8.

Early Modulation of Circulating MicroRNAs Levels in HER2-Positive Breast Cancer Patients Treated with Trastuzumab-Based Neoadjuvant Therapy.

Di Cosimo, Serena; Appierto, Valentina; Pizzamiglio, Sara; Silvestri, Marco; Baselga, José; Piccart, Martine; Huober, Jens; Izquierdo, Miguel; de la Pena, Lorena; Hilbers, Florentine S; de Azambuja, Evandro; Untch, Michael; Pusztai, Lajos; Pritchard, Kathleen; Nuciforo, Paolo; Vincent-Salomon, Anne; Symmans, Fraser; Apolone, Giovanni; de Braud, Filippo G; Iorio, Marilena V; Verderio, Paolo; Daidone, Maria Grazia.

Int J Mol Sci ; 21(4)2020 Feb 18.

Artigo em Inglês | MEDLINE | ID: mdl-32085669

9.

Neoadjuvant letrozole plus taselisib versus letrozole plus placebo in postmenopausal women with oestrogen receptor-positive, HER2-negative, early-stage breast cancer (LORELEI): a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial.

Saura, Cristina; Hlauschek, Dominik; Oliveira, Mafalda; Zardavas, Dimitrios; Jallitsch-Halper, Anita; de la Peña, Lorena; Nuciforo, Paolo; Ballestrero, Alberto; Dubsky, Peter; Lombard, Janine M; Vuylsteke, Peter; Castaneda, Carlos A; Colleoni, Marco; Santos Borges, Giuliano; Ciruelos, Eva; Fornier, Monica; Boer, Katalin; Bardia, Aditya; Wilson, Timothy R; Stout, Thomas J; Hsu, Jerry Y; Shi, Yi; Piccart, Martine; Gnant, Michael; Baselga, José; de Azambuja, Evandro.

Lancet Oncol ; 20(9): 1226-1238, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31402321

10.

Everolimus plus Exemestane for Hormone Receptor-Positive Advanced Breast Cancer: A PAM50 Intrinsic Subtype Analysis of BOLERO-2.

Prat, Aleix; Brase, Jan Christoph; Cheng, Yuan; Nuciforo, Paolo; Paré, Laia; Pascual, Tomás; Martínez, Débora; Galván, Patricia; Vidal, Maria; Adamo, Barbara; Hortobagyi, Gabriel N; Baselga, José; Ciruelos, Eva.

Oncologist ; 24(7): 893-900, 2019 07.

Artigo em Inglês | MEDLINE | ID: mdl-30679318

11.

Analysis of the PD-1/PD-L1 axis in human autoimmune thyroid disease: Insights into pathogenesis and clues to immunotherapy associated thyroid autoimmunity.

Álvarez-Sierra, Daniel; Marín-Sánchez, Ana; Ruiz-Blázquez, Paloma; de Jesús Gil, Carmen; Iglesias-Felip, Carmela; González, Óscar; Casteras, Anna; Costa, Roser Ferrer; Nuciforo, Paolo; Colobran, Roger; Pujol-Borrell, Ricardo.

J Autoimmun ; 103: 102285, 2019 09.

Artigo em Inglês | MEDLINE | ID: mdl-31182340

12.

HER2-enriched subtype as a predictor of pathological complete response following trastuzumab and lapatinib without chemotherapy in early-stage HER2-positive breast cancer (PAMELA): an open-label, single-group, multicentre, phase 2 trial.

Llombart-Cussac, Antonio; Cortés, Javier; Paré, Laia; Galván, Patricia; Bermejo, Begoña; Martínez, Noelia; Vidal, Maria; Pernas, Sònia; López, Rafael; Muñoz, Montserrat; Nuciforo, Paolo; Morales, Serafín; Oliveira, Mafalda; de la Peña, Lorena; Peláez, Alexandra; Prat, Aleix.

Lancet Oncol ; 18(4): 545-554, 2017 04.

Artigo em Inglês | MEDLINE | ID: mdl-28238593

13.

Assessing Tumor-infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method From the International Immunooncology Biomarkers Working Group: Part 1: Assessing the Host Immune Response, TILs in Invasive Breast Carcinoma and Ductal Carcinoma In Situ, Metastatic Tumor Deposits and Areas for Further Research.

Hendry, Shona; Salgado, Roberto; Gevaert, Thomas; Russell, Prudence A; John, Tom; Thapa, Bibhusal; Christie, Michael; van de Vijver, Koen; Estrada, M V; Gonzalez-Ericsson, Paula I; Sanders, Melinda; Solomon, Benjamin; Solinas, Cinzia; Van den Eynden, Gert G G M; Allory, Yves; Preusser, Matthias; Hainfellner, Johannes; Pruneri, Giancarlo; Vingiani, Andrea; Demaria, Sandra; Symmans, Fraser; Nuciforo, Paolo; Comerma, Laura; Thompson, E A; Lakhani, Sunil; Kim, Seong-Rim; Schnitt, Stuart; Colpaert, Cecile; Sotiriou, Christos; Scherer, Stefan J; Ignatiadis, Michail; Badve, Sunil; Pierce, Robert H; Viale, Giuseppe; Sirtaine, Nicolas; Penault-Llorca, Frederique; Sugie, Tomohagu; Fineberg, Susan; Paik, Soonmyung; Srinivasan, Ashok; Richardson, Andrea; Wang, Yihong; Chmielik, Ewa; Brock, Jane; Johnson, Douglas B; Balko, Justin; Wienert, Stephan; Bossuyt, Veerle; Michiels, Stefan; Ternes, Nils.

Adv Anat Pathol ; 24(5): 235-251, 2017 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-28777142

14.

Assessing Tumor-Infiltrating Lymphocytes in Solid Tumors: A Practical Review for Pathologists and Proposal for a Standardized Method from the International Immuno-Oncology Biomarkers Working Group: Part 2: TILs in Melanoma, Gastrointestinal Tract Carcinomas, Non-Small Cell Lung Carcinoma and Mesothelioma, Endometrial and Ovarian Carcinomas, Squamous Cell Carcinoma of the Head and Neck, Genitourinary Carcinomas, and Primary Brain Tumors.

Hendry, Shona; Salgado, Roberto; Gevaert, Thomas; Russell, Prudence A; John, Tom; Thapa, Bibhusal; Christie, Michael; van de Vijver, Koen; Estrada, M V; Gonzalez-Ericsson, Paula I; Sanders, Melinda; Solomon, Benjamin; Solinas, Cinzia; Van den Eynden, Gert G G M; Allory, Yves; Preusser, Matthias; Hainfellner, Johannes; Pruneri, Giancarlo; Vingiani, Andrea; Demaria, Sandra; Symmans, Fraser; Nuciforo, Paolo; Comerma, Laura; Thompson, E A; Lakhani, Sunil; Kim, Seong-Rim; Schnitt, Stuart; Colpaert, Cecile; Sotiriou, Christos; Scherer, Stefan J; Ignatiadis, Michail; Badve, Sunil; Pierce, Robert H; Viale, Giuseppe; Sirtaine, Nicolas; Penault-Llorca, Frederique; Sugie, Tomohagu; Fineberg, Susan; Paik, Soonmyung; Srinivasan, Ashok; Richardson, Andrea; Wang, Yihong; Chmielik, Ewa; Brock, Jane; Johnson, Douglas B; Balko, Justin; Wienert, Stephan; Bossuyt, Veerle; Michiels, Stefan; Ternes, Nils.

Adv Anat Pathol ; 24(6): 311-335, 2017 Nov.

Artigo em Inglês | MEDLINE | ID: mdl-28777143

15.

Quantification of HER family receptors in breast cancer.

Nuciforo, Paolo; Radosevic-Robin, Nina; Ng, Tony; Scaltriti, Maurizio.

Breast Cancer Res ; 17: 53, 2015 Apr 09.

Artigo em Inglês | MEDLINE | ID: mdl-25887735

16.

NUMB controls p53 tumour suppressor activity.

Colaluca, Ivan N; Tosoni, Daniela; Nuciforo, Paolo; Senic-Matuglia, Francesca; Galimberti, Viviana; Viale, Giuseppe; Pece, Salvatore; Di Fiore, Pier Paolo.

Nature ; 451(7174): 76-80, 2008 Jan 03.

Artigo em Inglês | MEDLINE | ID: mdl-18172499

17.

A whirl of radiomics-based biomarkers in cancer immunotherapy, why is large scale validation still lacking?

Ligero, Marta; Gielen, Bente; Navarro, Victor; Cresta Morgado, Pablo; Prior, Olivia; Dienstmann, Rodrigo; Nuciforo, Paolo; Trebeschi, Stefano; Beets-Tan, Regina; Sala, Evis; Garralda, Elena; Perez-Lopez, Raquel.

NPJ Precis Oncol ; 8(1): 42, 2024 Feb 21.

Artigo em Inglês | MEDLINE | ID: mdl-38383736

18.

Weakly Supervised Deep Learning Predicts Immunotherapy Response in Solid Tumors Based on PD-L1 Expression.

Ligero, Marta; Serna, Garazi; El Nahhas, Omar S M; Sansano, Irene; Mauchanski, Siarhei; Viaplana, Cristina; Calderaro, Julien; Toledo, Rodrigo A; Dienstmann, Rodrigo; Vanguri, Rami S; Sauter, Jennifer L; Sanchez-Vega, Francisco; Shah, Sohrab P; Ramón Y Cajal, Santiago; Garralda, Elena; Nuciforo, Paolo; Perez-Lopez, Raquel; Kather, Jakob Nikolas.

Cancer Res Commun ; 4(1): 92-102, 2024 01 11.

Artigo em Inglês | MEDLINE | ID: mdl-38126740

19.

Identification of Precise 3D CT Radiomics for Habitat Computation by Machine Learning in Cancer.

Prior, Olivia; Macarro, Carlos; Navarro, Víctor; Monreal, Camilo; Ligero, Marta; Garcia-Ruiz, Alonso; Serna, Garazi; Simonetti, Sara; Braña, Irene; Vieito, Maria; Escobar, Manuel; Capdevila, Jaume; Byrne, Annette T; Dienstmann, Rodrigo; Toledo, Rodrigo; Nuciforo, Paolo; Garralda, Elena; Grussu, Francesco; Bernatowicz, Kinga; Perez-Lopez, Raquel.

Radiol Artif Intell ; 6(2): e230118, 2024 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-38294307

20.

LOXL2-mediated chromatin compaction is required to maintain the oncogenic properties of triple-negative breast cancer cells.

Serra-Bardenys, Gemma; Blanco, Enrique; Escudero-Iriarte, Carmen; Serra-Camprubí, Queralt; Querol, Jessica; Pascual-Reguant, Laura; Morancho, Beatriz; Escorihuela, Marta; Tissera, Natalia Soledad; Sabé, Anna; Martín, Luna; Segura-Bayona, Sandra; Verde, Gaetano; Aiese Cigliano, Riccardo; Millanes-Romero, Alba; Jerónimo, Celia; Cebrià-Costa, Joan Pau; Nuciforo, Paolo; Simonetti, Sara; Viaplana, Cristina; Dienstmann, Rodrigo; Oliveira, Mafalda; Peg, Vicente; Stracker, Travis H; Arribas, Joaquín; Canals, Francesc; Villanueva, Josep; Di Croce, Luciano; García de Herreros, Antonio; Tian, Tian V; Peiró, Sandra.

FEBS J ; 2024 Mar 07.

Artigo em Inglês | MEDLINE | ID: mdl-38451841

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