Detalhe da pesquisa
1.
Mathematical models disentangle the role of IL-10 feedbacks in human monocytes upon proinflammatory activation.
J Biol Chem
; 299(10): 105205, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37660912
2.
A systems biology analysis of adrenergically stimulated adiponectin exocytosis in white adipocytes.
J Biol Chem
; 297(5): 101221, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34597667
3.
Perturbation biology links temporal protein changes to drug responses in a melanoma cell line.
PLoS Comput Biol
; 16(7): e1007909, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32667922
4.
Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes.
Biochem J
; 475(10): 1807-1820, 2018 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-29724916
5.
A systems biology analysis connects insulin receptor signaling with glucose transporter translocation in rat adipocytes.
J Biol Chem
; 292(27): 11206-11217, 2017 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495883
6.
Mathematical modeling of white adipocyte exocytosis predicts adiponectin secretion and quantifies the rates of vesicle exo- and endocytosis.
J Biol Chem
; 292(49): 20032-20043, 2017 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28972187
7.
LASSIM-A network inference toolbox for genome-wide mechanistic modeling.
PLoS Comput Biol
; 13(6): e1005608, 2017 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-28640810
8.
Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes.
J Biol Chem
; 291(30): 15806-19, 2016 07 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-27226562
9.
A single mechanism can explain network-wide insulin resistance in adipocytes from obese patients with type 2 diabetes.
J Biol Chem
; 289(48): 33215-30, 2014 Nov 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-25320095
10.
Insulin signaling in type 2 diabetes: experimental and modeling analyses reveal mechanisms of insulin resistance in human adipocytes.
J Biol Chem
; 288(14): 9867-9880, 2013 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23400783
11.
A unified framework for prediction of liver steatosis dynamics in response to different diet and drug interventions.
Clin Nutr
; 43(6): 1532-1543, 2024 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-38754305
12.
A comprehensive mechanistic model of adipocyte signaling with layers of confidence.
NPJ Syst Biol Appl
; 9(1): 24, 2023 06 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-37286693
13.
A multi-scale digital twin for adiposity-driven insulin resistance in humans: diet and drug effects.
Diabetol Metab Syndr
; 15(1): 250, 2023 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-38044443
14.
A hierarchical whole-body modeling approach elucidates the link between in Vitro insulin signaling and in Vivo glucose homeostasis.
J Biol Chem
; 286(29): 26028-41, 2011 Jul 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-21572040
15.
An Updated Organ-Based Multi-Level Model for Glucose Homeostasis: Organ Distributions, Timing, and Impact of Blood Flow.
Front Physiol
; 12: 619254, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34140893
16.
A systems biology analysis of lipolysis and fatty acid release from adipocytes in vitro and from adipose tissue in vivo.
PLoS One
; 16(12): e0261681, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34972146
17.
Mechanisms of a Sustained Anti-inflammatory Drug Response in Alveolar Macrophages Unraveled with Mathematical Modeling.
CPT Pharmacometrics Syst Pharmacol
; 9(12): 707-717, 2020 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-33217190
18.
Trigger factors in takotsubo syndrome - A systematic review of case reports.
Eur J Intern Med
; 63: 62-68, 2019 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-30833207
19.
Cross-talks via mTORC2 can explain enhanced activation in response to insulin in diabetic patients.
Biosci Rep
; 37(1)2017 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-27986865
20.
Systems biology reveals uncoupling beyond UCP1 in human white fat-derived beige adipocytes.
NPJ Syst Biol Appl
; 3: 29, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28983409