Detalhe da pesquisa
1.
Exploiting the intrinsic misfolding propensity of the KRAS oncoprotein.
Proc Natl Acad Sci U S A
; 120(9): e2214921120, 2023 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36812200
2.
The structural basis for an on-off switch controlling Gßγ-mediated inhibition of TRPM3 channels.
Proc Natl Acad Sci U S A
; 117(46): 29090-29100, 2020 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-33122432
3.
Allosteric binding site in a Cys-loop receptor ligand-binding domain unveiled in the crystal structure of ELIC in complex with chlorpromazine.
Proc Natl Acad Sci U S A
; 113(43): E6696-E6703, 2016 10 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27791038
4.
An in vitro assay to investigate venom neurotoxin activity on muscle-type nicotinic acetylcholine receptor activation and for the discovery of toxin-inhibitory molecules.
Biochem Pharmacol
; 216: 115758, 2023 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-37604290
5.
The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Nat Commun
; 13(1): 4543, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35927270
6.
Author Correction: The molecular mechanism of snake short-chain α-neurotoxin binding to muscle-type nicotinic acetylcholine receptors.
Nat Commun
; 15(1): 4532, 2024 May 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38806512
7.
Structure-Guided Exploration of SDS22 Interactions with Protein Phosphatase PP1 and the Splicing Factor BCLAF1.
Structure
; 27(3): 507-518.e5, 2019 03 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30661852
8.
Functional and Biochemical Characterization of Alvinella pompejana Cys-Loop Receptor Homologues.
PLoS One
; 11(3): e0151183, 2016.
Artigo
em Inglês
| MEDLINE | ID: mdl-26999666
9.
Structure of the SthK carboxy-terminal region reveals a gating mechanism for cyclic nucleotide-modulated ion channels.
PLoS One
; 10(1): e0116369, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-25625648
10.
Structural insights into Cys-loop receptor function and ligand recognition.
Biochem Pharmacol
; 86(8): 1042-53, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23850718
11.
Insights into the structural determinants required for high-affinity binding of chiral cyclopropane-containing ligands to α4ß2-nicotinic acetylcholine receptors: an integrated approach to behaviorally active nicotinic ligands.
J Med Chem
; 55(18): 8028-37, 2012 Sep 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-22928944