Detalhe da pesquisa
1.
Discovery of potent BET bromodomain 1 stereoselective inhibitors using DNA-encoded chemical library selections.
Proc Natl Acad Sci U S A
; 119(22): e2122506119, 2022 05 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-35622893
2.
Discovery and characterization of bromodomain 2-specific inhibitors of BRDT.
Proc Natl Acad Sci U S A
; 118(9)2021 03 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33637650
3.
DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors.
Proc Natl Acad Sci U S A
; 118(36)2021 09 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34426525
4.
Discovery of potent thrombin inhibitors from a protease-focused DNA-encoded chemical library.
Proc Natl Acad Sci U S A
; 117(29): 16782-16789, 2020 07 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-32641511
5.
Metabolism of a Selective Serotonin and Norepinephrine Reuptake Inhibitor Duloxetine in Liver Microsomes and Mice.
Drug Metab Dispos
; 50(2): 128-139, 2022 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34785568
6.
Mammalian Target of Rapamycin Complex 2 Signaling Is Required for Liver Regeneration in a Cholestatic Liver Injury Murine Model.
Am J Pathol
; 190(7): 1414-1426, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32275903
7.
Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library.
Bioorg Med Chem
; 48: 116387, 2021 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-34571488
8.
Equivalency challenge: Evaluation of Lipodox® as the generic equivalent for Doxil® in a human ovarian cancer orthotropic mouse model.
Gynecol Oncol
; 141(2): 357-363, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26946092
9.
DNA-encoded chemical libraries yield non-covalent and non-peptidic SARS-CoV-2 main protease inhibitors.
Commun Chem
; 6(1): 164, 2023 Aug 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37542196
10.
Corrigendum to 'Equivalency challenge: evaluation of Lipodox® as the generic equivalent for Doxil® in a human ovarian cancer orthotropic mouse model' [Gynecol. Oncol. 141 (2016) 357-363].
Gynecol Oncol
; 144(2): 448, 2017 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28089052
11.
Homogeneous and Functional Group Tolerant Ring-Closing Metathesis for DNA-Encoded Chemical Libraries.
ACS Comb Sci
; 22(2): 80-88, 2020 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31913011
12.
Identifying Oxacillinase-48 Carbapenemase Inhibitors Using DNA-Encoded Chemical Libraries.
ACS Infect Dis
; 6(5): 1214-1227, 2020 05 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32182432