Detalhe da pesquisa
1.
Obesity-associated microbiota contributes to mucus layer defects in genetically obese mice.
J Biol Chem
; 295(46): 15712-15726, 2020 11 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-32900852
2.
Calcium-activated chloride channel regulator 1 (CLCA1) forms non-covalent oligomers in colonic mucus and has mucin 2-processing properties.
J Biol Chem
; 294(45): 17075-17089, 2019 11 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31570526
3.
The mucus and mucins of the goblet cells and enterocytes provide the first defense line of the gastrointestinal tract and interact with the immune system.
Immunol Rev
; 260(1): 8-20, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24942678
4.
Microbial experience through housing in a farmyard-type environment alters intestinal barrier properties in mouse colons.
Sci Rep
; 13(1): 13701, 2023 08 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-37607995
5.
Proteolytic processing of galectin-3 by meprin metalloproteases is crucial for host-microbiome homeostasis.
Sci Adv
; 9(13): eadf4055, 2023 03 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37000885
6.
Trans-Golgi protein TVP23B regulates host-microbe interactions via Paneth cell homeostasis and Goblet cell glycosylation.
Nat Commun
; 14(1): 3652, 2023 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37339972
7.
Diet, microbiota, and the mucus layer: The guardians of our health.
Front Immunol
; 13: 953196, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-36177011
8.
Transglutaminase 3 crosslinks the secreted gel-forming mucus component Mucin-2 and stabilizes the colonic mucus layer.
Nat Commun
; 13(1): 45, 2022 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35017479
9.
An intercrypt subpopulation of goblet cells is essential for colonic mucus barrier function.
Science
; 372(6539)2021 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-33859001
10.
Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium.
Front Physiol
; 10: 694, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31263421
11.
Corrigendum: Normal Calcium-Activated Anion Secretion in a Mouse Selectively Lacking TMEM16A in Intestinal Epithelium.
Front Physiol
; 10: 1040, 2019.
Artigo
em Inglês
| MEDLINE | ID: mdl-31501653
12.
The Nlrp6 inflammasome is not required for baseline colonic inner mucus layer formation or function.
J Exp Med
; 216(11): 2602-2618, 2019 11 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31420376
13.
Calcium-activated Chloride Channel Regulator 1 (CLCA1) Controls Mucus Expansion in Colon by Proteolytic Activity.
EBioMedicine
; 33: 134-143, 2018 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-29885864
14.
A sentinel goblet cell guards the colonic crypt by triggering Nlrp6-dependent Muc2 secretion.
Science
; 352(6293): 1535-42, 2016 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27339979
15.
The Goblet Cell Protein Clca1 (Alias mClca3 or Gob-5) Is Not Required for Intestinal Mucus Synthesis, Structure and Barrier Function in Naive or DSS-Challenged Mice.
PLoS One
; 10(7): e0131991, 2015.
Artigo
em Inglês
| MEDLINE | ID: mdl-26162072