Detalhe da pesquisa
1.
Arylsulfonamidopiperidone derivatives as a novel class of factor Xa inhibitors.
Bioorg Med Chem Lett
; 21(24): 7516-21, 2011 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-22041058
2.
Synthesis, SAR, and atropisomerism of imidazolopyrimidine DPP4 inhibitors.
Bioorg Med Chem Lett
; 20(21): 6273-6, 2010 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20833042
3.
Aroylguanidine-based factor Xa inhibitors: the discovery of BMS-344577.
Bioorg Med Chem Lett
; 19(24): 6882-9, 2009 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-19896847
4.
Cyanoguanidine-based lactam derivatives as a novel class of orally bioavailable factor Xa inhibitors.
Bioorg Med Chem Lett
; 19(15): 4034-41, 2009 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-19541481
5.
Synthesis and evaluation of acylguanidine FXa inhibitors.
Bioorg Med Chem Lett
; 18(16): 4696-9, 2008 Aug 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-18644722
6.
Discovery of Clinical Candidate BMS-823778 as an Inhibitor of Human 11ß-Hydroxysteroid Dehydrogenase Type 1 (11ß-HSD-1).
ACS Med Chem Lett
; 9(12): 1170-1174, 2018 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-30613321
7.
Discovery of Clinical Candidate 2-((2S,6S)-2-Phenyl-6-hydroxyadamantan-2-yl)-1-(3'-hydroxyazetidin-1-yl)ethanone [BMS-816336], an Orally Active Novel Selective 11ß-Hydroxysteroid Dehydrogenase Type 1 Inhibitor.
J Med Chem
; 60(12): 4932-4948, 2017 06 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-28537398
8.
Catalytic, Enantioselective Cyclopropanation of Allylic Alcohols. Substrate Generality.
J Org Chem
; 62(3): 584-594, 1997 Feb 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-11671453
9.
Enantioselective Cyclopropanation of Allylic Alcohols. The Effect of Zinc Iodide.
J Org Chem
; 62(10): 3390-3401, 1997 May 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-11671728
10.
Solution and Solid-State Studies of a Chiral Zinc-Sulfonamide Complex Relevant to Enantioselective Cyclopropanations.
Angew Chem Int Ed Engl
; 37(8): 1149-1151, 1998 May 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-29711011
11.
Optimization of 1,2,4-Triazolopyridines as Inhibitors of Human 11ß-Hydroxysteroid Dehydrogenase Type 1 (11ß-HSD-1).
ACS Med Chem Lett
; 5(7): 803-8, 2014 Jul 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-25050169
12.
Discovery of 6-(aminomethyl)-5-(2,4-dichlorophenyl)-7-methylimidazo[1,2-a]pyrimidine-2-carboxamides as potent, selective dipeptidyl peptidase-4 (DPP4) inhibitors.
J Med Chem
; 53(15): 5620-8, 2010 Aug 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-20684603
13.
Amino(methyl) pyrrolidines as novel scaffolds for factor Xa inhibitors.
Bioorg Med Chem Lett
; 17(21): 5952-8, 2007 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-17855089
14.
Ketene aminal-based lactam derivatives as a novel class of orally active FXa inhibitors.
Bioorg Med Chem Lett
; 15(24): 5453-8, 2005 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-16213711