Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Estrogen Receptor ß Modulates Apoptosis Complexes and the Inflammasome to Drive the Pathogenesis of Endometriosis.

Han, Sang Jun; Jung, Sung Yun; Wu, San-Pin; Hawkins, Shannon M; Park, Mi Jin; Kyo, Satoru; Qin, Jun; Lydon, John P; Tsai, Sophia Y; Tsai, Ming-Jer; DeMayo, Francesco J; O'Malley, Bert W.

Cell ; 163(4): 960-74, 2015 Nov 05.

Artigo em Inglês | MEDLINE | ID: mdl-26544941

2.

Structural Insights of Transcriptionally Active, Full-Length Androgen Receptor Coactivator Complexes.

Yu, Xinzhe; Yi, Ping; Hamilton, Ross A; Shen, Hong; Chen, Muyuan; Foulds, Charles E; Mancini, Michael A; Ludtke, Steven J; Wang, Zhao; O'Malley, Bert W.

Mol Cell ; 79(5): 812-823.e4, 2020 09 03.

Artigo em Inglês | MEDLINE | ID: mdl-32668201

3.

Analysis of the human endogenous coregulator complexome.

Malovannaya, Anna; Lanz, Rainer B; Jung, Sung Yun; Bulynko, Yaroslava; Le, Nguyen T; Chan, Doug W; Ding, Chen; Shi, Yi; Yucer, Nur; Krenciute, Giedre; Kim, Beom-Jun; Li, Chunshu; Chen, Rui; Li, Wei; Wang, Yi; O'Malley, Bert W; Qin, Jun.

Cell ; 145(5): 787-99, 2011 May 27.

Artigo em Inglês | MEDLINE | ID: mdl-21620140

4.

SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription.

Panigrahi, Anil K; Foulds, Charles E; Lanz, Rainer B; Hamilton, Ross A; Yi, Ping; Lonard, David M; Tsai, Ming-Jer; Tsai, Sophia Y; O'Malley, Bert W.

Mol Cell ; 70(4): 679-694.e7, 2018 05 17.

Artigo em Inglês | MEDLINE | ID: mdl-29775582

5.

Enhancer-promoter entanglement explains their transcriptional interdependence.

Panigrahi, Anil K; Lonard, David M; O'Malley, Bert W.

Proc Natl Acad Sci U S A ; 120(4): e2216436120, 2023 01 24.

Artigo em Inglês | MEDLINE | ID: mdl-36656865

6.

TRAF4-mediated nonproteolytic ubiquitination of androgen receptor promotes castration-resistant prostate cancer.

Singh, Ramesh; Meng, Huan; Shen, Tao; Lumahan, Lance Edward V; Nguyen, Steven; Shen, Hong; Dasgupta, Subhamoy; Qin, Li; Karri, Dileep; Zhu, Bokai; Yang, Feng; Coarfa, Cristian; O'Malley, Bert W; Yi, Ping.

Proc Natl Acad Sci U S A ; 120(20): e2218229120, 2023 05 16.

Artigo em Inglês | MEDLINE | ID: mdl-37155905

7.

Steroid receptor coactivator 3 is a key modulator of regulatory T cell-mediated tumor evasion.

Han, Sang Jun; Jain, Prashi; Gilad, Yosef; Xia, Yan; Sung, Nuri; Park, Mi Jin; Dean, Adam M; Lanz, Rainer B; Xu, Jianming; Dacso, Clifford C; Lonard, David M; O'Malley, Bert W.

Proc Natl Acad Sci U S A ; 120(23): e2221707120, 2023 06 06.

Artigo em Inglês | MEDLINE | ID: mdl-37253006

8.

Structural and Functional Impacts of ER Coactivator Sequential Recruitment.

Yi, Ping; Wang, Zhao; Feng, Qin; Chou, Chao-Kai; Pintilie, Grigore D; Shen, Hong; Foulds, Charles E; Fan, Guizhen; Serysheva, Irina; Ludtke, Steven J; Schmid, Michael F; Hung, Mien-Chie; Chiu, Wah; O'Malley, Bert W.

Mol Cell ; 67(5): 733-743.e4, 2017 Sep 07.

Artigo em Inglês | MEDLINE | ID: mdl-28844863

9.

Steroid receptor coactivator-2 drives epithelial reprogramming that enables murine embryo implantation.

Maurya, Vineet K; Szwarc, Maria M; Lonard, David M; Kommagani, Ramakrishna; Wu, San Pin; O'Malley, Bert W; DeMayo, Francesco J; Lydon, John P.

FASEB J ; 37(12): e23313, 2023 12.

Artigo em Inglês | MEDLINE | ID: mdl-37962238

10.

Metabolic enzyme PFKFB4 activates transcriptional coactivator SRC-3 to drive breast cancer.

Dasgupta, Subhamoy; Rajapakshe, Kimal; Zhu, Bokai; Nikolai, Bryan C; Yi, Ping; Putluri, Nagireddy; Choi, Jong Min; Jung, Sung Y; Coarfa, Cristian; Westbrook, Thomas F; Zhang, Xiang H-F; Foulds, Charles E; Tsai, Sophia Y; Tsai, Ming-Jer; O'Malley, Bert W.

Nature ; 556(7700): 249-254, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29615789

11.

Cell lineage tracing links ERα loss in Erbb2-positive breast cancers to the arising of a highly aggressive breast cancer subtype.

Ding, Yunfeng; Liu, Yonghong; Lee, Dong-Kee; Tong, Zhangwei; Yu, Xiaobin; Li, Yi; Xu, Yong; Lanz, Rainer B; O'Malley, Bert W; Xu, Jianming.

Proc Natl Acad Sci U S A ; 118(21)2021 05 25.

Artigo em Inglês | MEDLINE | ID: mdl-34006643

12.

Aging-associated REGÎ³ proteasome decline predisposes to tauopathy.

Tu, Jialu; Zhang, Haiyang; Yang, Ting; Liu, Yun; Kibreab, Solomon; Zhang, Yunpeng; Gao, Liangcai; Moses, Robb E; O'Malley, Bert W; Xiao, Jianru; Li, Xiaotao.

J Biol Chem ; 298(11): 102571, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-36209822

13.

12-h clock regulation of genetic information flow by XBP1s.

Pan, Yinghong; Ballance, Heather; Meng, Huan; Gonzalez, Naomi; Kim, Sam-Moon; Abdurehman, Leymaan; York, Brian; Chen, Xi; Schnytzer, Yisrael; Levy, Oren; Dacso, Clifford C; McClung, Colleen A; O'Malley, Bert W; Liu, Silvia; Zhu, Bokai.

PLoS Biol ; 18(1): e3000580, 2020 01.

Artigo em Inglês | MEDLINE | ID: mdl-31935211

14.

Coactivator-Dependent Oscillation of Chromatin Accessibility Dictates Circadian Gene Amplitude via REV-ERB Loading.

Zhu, Bokai; Gates, Leah A; Stashi, Erin; Dasgupta, Subhamoy; Gonzales, Naomi; Dean, Adam; Dacso, Clifford C; York, Brian; O'Malley, Bert W.

Mol Cell ; 60(5): 769-783, 2015 Dec 03.

Artigo em Inglês | MEDLINE | ID: mdl-26611104

15.

Structure of a biologically active estrogen receptor-coactivator complex on DNA.

Yi, Ping; Wang, Zhao; Feng, Qin; Pintilie, Grigore D; Foulds, Charles E; Lanz, Rainer B; Ludtke, Steven J; Schmid, Michael F; Chiu, Wah; O'Malley, Bert W.

Mol Cell ; 57(6): 1047-1058, 2015 Mar 19.

Artigo em Inglês | MEDLINE | ID: mdl-25728767

16.

A steroid receptor coactivator stimulator (MCB-613) attenuates adverse remodeling after myocardial infarction.

Mullany, Lisa K; Rohira, Aarti D; Leach, John P; Kim, Jong H; Monroe, Tanner O; Ortiz, Andrea R; Stork, Brittany; Gaber, M Waleed; Sarkar, Poonam; Sikora, Andrew G; Rosengart, Todd K; York, Brian; Song, Yongcheng; Dacso, Clifford C; Lonard, David M; Martin, James F; O'Malley, Bert W.

Proc Natl Acad Sci U S A ; 117(49): 31353-31364, 2020 12 08.

Artigo em Inglês | MEDLINE | ID: mdl-33229578

17.

The E3 ligase TRAF4 promotes IGF signaling by mediating atypical ubiquitination of IRS-1.

Yu, Wenjuan; Singh, Ramesh; Wang, Zhao; O'Malley, Bert W; Yi, Ping.

J Biol Chem ; 296: 100739, 2021.

Artigo em Inglês | MEDLINE | ID: mdl-33991522

18.

Steroid receptor coactivator-3 inhibition generates breast cancer antitumor immune microenvironment.

Han, Sang Jun; Sung, Nuri; Wang, Jin; O'Malley, Bert W; Lonard, David M.

Breast Cancer Res ; 24(1): 73, 2022 10 31.

Artigo em Inglês | MEDLINE | ID: mdl-36316775

19.

Oleuropein suppresses endometriosis progression and improves the fertility of mice with endometriosis.

Park, Yuri; Cho, Yeon Jean; Sung, Nuri; Park, Mi Jin; Guan, Xiaoming; Gibbons, William E; O'Malley, Bert W; Han, Sang Jun.

J Biomed Sci ; 29(1): 100, 2022 Nov 22.

Artigo em Inglês | MEDLINE | ID: mdl-36419064

20.

Masters of the genome.

O'Malley, Bert W.

Nat Rev Mol Cell Biol ; 11(5): 311, 2010 May.

Artigo em Inglês | MEDLINE | ID: mdl-20422740

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