Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Krebs Cycle Reborn in Macrophage Immunometabolism.

Ryan, Dylan G; O'Neill, Luke A J.

Annu Rev Immunol ; 38: 289-313, 2020 04 26.

Artigo em Inglês | MEDLINE | ID: mdl-31986069

2.

From periphery to center stage: 50 years of advancements in innate immunity.

Carpenter, Susan; O'Neill, Luke A J.

Cell ; 187(9): 2030-2051, 2024 Apr 25.

Artigo em Inglês | MEDLINE | ID: mdl-38670064

3.

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Murphy, Michael P; O'Neill, Luke A J.

Cell ; 174(4): 780-784, 2018 08 09.

Artigo em Inglês | MEDLINE | ID: mdl-30096309

4.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

Mills, Evanna L; Kelly, Beth; Logan, Angela; Costa, Ana S H; Varma, Mukund; Bryant, Clare E; Tourlomousis, Panagiotis; Däbritz, J Henry M; Gottlieb, Eyal; Latorre, Isabel; Corr, Sinéad C; McManus, Gavin; Ryan, Dylan; Jacobs, Howard T; Szibor, Marten; Xavier, Ramnik J; Braun, Thomas; Frezza, Christian; Murphy, Michael P; O'Neill, Luke A.

Cell ; 167(2): 457-470.e13, 2016 Oct 06.

Artigo em Inglês | MEDLINE | ID: mdl-27667687

5.

How Low Cholesterol Is Good for Anti-viral Immunity.

O'Neill, Luke A J.

Cell ; 163(7): 1572-4, 2015 Dec 17.

Artigo em Inglês | MEDLINE | ID: mdl-26687349

6.

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases.

Murphy, Michael P; O'Neill, Luke A J.

Nature ; 626(7998): 271-279, 2024 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-38326590

7.

Mitochondria are the powerhouses of immunity.

Mills, Evanna L; Kelly, Beth; O'Neill, Luke A J.

Nat Immunol ; 18(5): 488-498, 2017 04 18.

Artigo em Inglês | MEDLINE | ID: mdl-28418387

8.

Creating ATP via creatine kinase B for NLRP3 activation.

Toller-Kawahisa, Juliana E; O'Neill, Luke A J.

Nat Immunol ; 23(5): 653-655, 2022 05.

Artigo em Inglês | MEDLINE | ID: mdl-35484409

9.

A guiding map for inflammation.

Netea, Mihai G; Balkwill, Frances; Chonchol, Michel; Cominelli, Fabio; Donath, Marc Y; Giamarellos-Bourboulis, Evangelos J; Golenbock, Douglas; Gresnigt, Mark S; Heneka, Michael T; Hoffman, Hal M; Hotchkiss, Richard; Joosten, Leo A B; Kastner, Daniel L; Korte, Martin; Latz, Eicke; Libby, Peter; Mandrup-Poulsen, Thomas; Mantovani, Alberto; Mills, Kingston H G; Nowak, Kristen L; O'Neill, Luke A; Pickkers, Peter; van der Poll, Tom; Ridker, Paul M; Schalkwijk, Joost; Schwartz, David A; Siegmund, Britta; Steer, Clifford J; Tilg, Herbert; van der Meer, Jos W M; van de Veerdonk, Frank L; Dinarello, Charles A.

Nat Immunol ; 18(8): 826-831, 2017 Jul 19.

Artigo em Inglês | MEDLINE | ID: mdl-28722720

10.

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.

Hooftman, Alexander; Peace, Christian G; Ryan, Dylan G; Day, Emily A; Yang, Ming; McGettrick, Anne F; Yin, Maureen; Montano, Erica N; Huo, Lihong; Toller-Kawahisa, Juliana E; Zecchini, Vincent; Ryan, Tristram A J; Bolado-Carrancio, Alfonso; Casey, Alva M; Prag, Hiran A; Costa, Ana S H; De Los Santos, Gabriela; Ishimori, Mariko; Wallace, Daniel J; Venuturupalli, Swamy; Nikitopoulou, Efterpi; Frizzell, Norma; Johansson, Cecilia; Von Kriegsheim, Alexander; Murphy, Michael P; Jefferies, Caroline; Frezza, Christian; O'Neill, Luke A J.

Nature ; 615(7952): 490-498, 2023 03.

Artigo em Inglês | MEDLINE | ID: mdl-36890227

11.

Targeting mitochondria to beat HIV-1.

Day, Emily A; O'Neill, Luke A J.

Nat Immunol ; 22(4): 398-399, 2021 04.

Artigo em Inglês | MEDLINE | ID: mdl-33767428

12.

Immune-mediated inflammation across disease boundaries: breaking down research silos.

Buckley, Christopher D; Chernajovsky, Lorna; Chernajovsky, Yuti; Modis, Louise K; O'Neill, Luke A; Brown, Doug; Connor, Rachel; Coutts, David; Waterman, Elizabeth A; Tak, Paul P.

Nat Immunol ; 22(11): 1344-1348, 2021 11.

Artigo em Inglês | MEDLINE | ID: mdl-34675389

13.

Author Correction: A guiding map for inflammation.

Netea, Mihai G; Balkwill, Frances; Chonchol, Michel; Cominelli, Fabio; Donath, Marc Y; Giamarellos-Bourboulis, Evangelos J; Golenbock, Douglas; Gresnigt, Mark S; Heneka, Michael T; Hoffman, Hal M; Hotchkiss, Richard; Joosten, Leo A B; Kastner, Daniel L; Korte, Martin; Latz, Eicke; Libby, Peter; Mandrup-Poulsen, Thomas; Mantovani, Alberto; Mills, Kingston H G; Nowak, Kristen L; O'Neill, Luke A; Pickkers, Peter; van der Poll, Tom; Ridker, Paul M; Schalkwijk, Joost; Schwartz, David A; Siegmund, Britta; Steer, Clifford J; Tilg, Herbert; van der Meer, Jos W M; van de Veerdonk, Frank L; Dinarello, Charles A.

Nat Immunol ; 22(2): 254, 2021 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-33288963

14.

Cytokine-like Roles for Metabolites in Immunity.

Zaslona, Zbigniew; O'Neill, Luke A J.

Mol Cell ; 78(5): 814-823, 2020 06 04.

Artigo em Inglês | MEDLINE | ID: mdl-32333837

15.

Metabolic regulation of type I interferon production.

O'Carroll, Shane M; Henkel, Fiona D R; O'Neill, Luke A J.

Immunol Rev ; 323(1): 276-287, 2024 May.

Artigo em Inglês | MEDLINE | ID: mdl-38465724

16.

How should we talk about metabolism?

Murphy, Michael P; O'Neill, Luke A J.

Nat Immunol ; 21(7): 713-715, 2020 07.

Artigo em Inglês | MEDLINE | ID: mdl-32409776

17.

Unlocking potential: the role of the electron transport chain in immunometabolism.

Zotta, Alessia; O'Neill, Luke A J; Yin, Maureen.

Trends Immunol ; 45(4): 259-273, 2024 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-38503657

18.

"Transflammation": when innate immunity meets induced pluripotency.

O'Neill, Luke A J.

Cell ; 151(3): 471-3, 2012 Oct 26.

Artigo em Inglês | MEDLINE | ID: mdl-23101619

19.

NLRP12 drives PANoptosis in response to heme.

Henkel, Fiona D R; O'Neill, Luke A J.

Trends Immunol ; 44(8): 574-576, 2023 08.

Artigo em Inglês | MEDLINE | ID: mdl-37423881

20.

4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development.

Yin, Maureen; Wadhwa, Ridhima; Marshall, Jacqueline E; Gillis, Caitlin M; Kim, Richard Y; Dua, Kamal; Palsson-McDermott, Eva M; Fallon, Padraic G; Hansbro, Philip M; O'Neill, Luke A J.

J Immunol ; 212(1): 13-23, 2024 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-37991425

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Krebs Cycle Reborn in Macrophage Immunometabolism.

From periphery to center stage: 50 years of advancements in innate immunity.

Krebs Cycle Reimagined: The Emerging Roles of Succinate and Itaconate as Signal Transducers.

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages.

How Low Cholesterol Is Good for Anti-viral Immunity.

A break in mitochondrial endosymbiosis as a basis for inflammatory diseases.

Mitochondria are the powerhouses of immunity.

Creating ATP via creatine kinase B for NLRP3 activation.

A guiding map for inflammation.

Macrophage fumarate hydratase restrains mtRNA-mediated interferon production.

Targeting mitochondria to beat HIV-1.

Immune-mediated inflammation across disease boundaries: breaking down research silos.

Author Correction: A guiding map for inflammation.

Cytokine-like Roles for Metabolites in Immunity.

Metabolic regulation of type I interferon production.

How should we talk about metabolism?

Unlocking potential: the role of the electron transport chain in immunometabolism.

"Transflammation": when innate immunity meets induced pluripotency.

NLRP12 drives PANoptosis in response to heme.

4-Octyl Itaconate Alleviates Airway Eosinophilic Inflammation by Suppressing Chemokines and Eosinophil Development.