Detalhe da pesquisa
1.
A guide to cell death pathways.
Nat Rev Mol Cell Biol
; 25(5): 379-395, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38110635
2.
TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging.
Cell
; 174(6): 1477-1491.e19, 2018 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30146158
3.
Regulation of RIP1 kinase signalling at the crossroads of inflammation and cell death.
Nat Rev Mol Cell Biol
; 14(11): 727-36, 2013 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-24129419
4.
Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases.
Nat Rev Neurosci
; 20(1): 19-33, 2019 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30467385
5.
Corrigendum: Chaperone-mediated autophagy degrades mutant p53.
Genes Dev
; 30(7): 870, 2016 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27036968
6.
Targeting RIPK1 for the treatment of human diseases.
Proc Natl Acad Sci U S A
; 116(20): 9714-9722, 2019 05 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31048504
7.
Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis.
Proc Natl Acad Sci U S A
; 115(26): E5944-E5953, 2018 06 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-29891719
8.
Chaperone-mediated autophagy degrades mutant p53.
Genes Dev
; 27(15): 1718-30, 2013 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23913924
9.
RIPK1 mediates a disease-associated microglial response in Alzheimer's disease.
Proc Natl Acad Sci U S A
; 114(41): E8788-E8797, 2017 10 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28904096
10.
Safety, pharmacokinetics, and target engagement of a brain penetrant RIPK1 inhibitor, SAR443820 (DNL788), in healthy adult participants.
Clin Transl Sci
; 17(1): e13690, 2024 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-38010108
11.
Identification of small molecule inhibitors of neurite loss induced by Aß peptide using high content screening.
J Biol Chem
; 287(12): 8714-23, 2012 Mar 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-22277654
12.
Protocol for establishing a global ischemia model using a 4-vessel occlusion in rats.
STAR Protoc
; 4(4): 102630, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38264871
13.
Microglia ferroptosis is regulated by SEC24B and contributes to neurodegeneration.
Nat Neurosci
; 26(1): 12-26, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36536241
14.
Ischemic preconditioning blocks BAD translocation, Bcl-xL cleavage, and large channel activity in mitochondria of postischemic hippocampal neurons.
Proc Natl Acad Sci U S A
; 105(12): 4892-7, 2008 Mar 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-18347331
15.
RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis.
Cell Rep
; 35(6): 109112, 2021 05 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33979622
16.
Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.
Nat Neurosci
; 24(3): 355-367, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33495636
17.
The SARS-CoV-2 main protease Mpro causes microvascular brain pathology by cleaving NEMO in brain endothelial cells.
Nat Neurosci
; 24(11): 1522-1533, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34675436
18.
Receptor-interacting protein kinase 1 (RIPK1) as a therapeutic target.
Nat Rev Drug Discov
; 19(8): 553-571, 2020 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-32669658
19.
CSF1R signaling is a regulator of pathogenesis in progressive MS.
Cell Death Dis
; 11(10): 904, 2020 10 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-33097690
20.
ABIN-1 heterozygosity sensitizes to innate immune response in both RIPK1-dependent and RIPK1-independent manner.
Cell Death Differ
; 26(6): 1077-1088, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30341420