RESUMO
The first bovine parechovirus (Bo_ParV) was reported in 2021, and currently, only two nearly complete genome sequences of Bo_ParV are available. In this study, we detected Bo_ParVs in 10 out of 158 bovine fecal samples tested using real-time RT-PCR, and Bo_ParVs were isolated from three of these samples using MA104 cells. Analysis of the P1 region revealed that Bo_ParVs shared high pairwise amino acid sequence similarity (≥ 95.7% identity), suggesting antigenic similarity among Bo_ParVs, whereas nucleotide sequence identity values (≥ 84.8%) indicated more variability. A recombination breakpoint was identified in the 2B region, which may influence the evolution of this virus.
Assuntos
Bovinos , Parechovirus , Animais , Bovinos/virologia , Variação Genética , Genótipo , Parechovirus/genética , Filogenia , PrevalênciaRESUMO
To investigate the effects of retrosplenial cortex (RSC) lesions on episodic-like memory, we used four types of object recognition tasks. What task examined memory of object identities. Where task examined memory of object locations. When task examined memory of the temporal order of presented objects. Episodic task examined the integrated memory of the identity, location, and temporal order of presented objects. Rats with the RSC lesions preferred novel objects in the What and Where tasks, whereas they showed no such preference in the When and Episodic tasks, suggesting that rats with the RSC lesions have deficits in memory for temporal order and that this might cause deficits in episodic-like memory.