Detalhe da pesquisa
1.
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damage.
Cell
; 136(3): 420-34, 2009 Feb 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-19203578
2.
TLR9 expression in chronic lymphocytic leukemia identifies a promigratory subpopulation and novel therapeutic target.
Blood
; 137(22): 3064-3078, 2021 06 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33512408
3.
Integrative analysis of spontaneous CLL regression highlights genetic and microenvironmental interdependency in CLL.
Blood
; 135(6): 411-428, 2020 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31794600
4.
USP7 inhibition alters homologous recombination repair and targets CLL cells independently of ATM/p53 functional status.
Blood
; 130(2): 156-166, 2017 07 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-28495793
5.
ATR inhibition induces synthetic lethality and overcomes chemoresistance in TP53- or ATM-defective chronic lymphocytic leukemia cells.
Blood
; 127(5): 582-95, 2016 Feb 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-26563132
6.
Clinical impact of clonal and subclonal TP53, SF3B1, BIRC3, NOTCH1, and ATM mutations in chronic lymphocytic leukemia.
Blood
; 127(17): 2122-30, 2016 04 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-26837699
7.
Targeting the Ataxia Telangiectasia Mutated-null phenotype in chronic lymphocytic leukemia with pro-oxidants.
Haematologica
; 100(8): 1076-85, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25840602
8.
A multi-centre phase I trial of the PARP inhibitor olaparib in patients with relapsed chronic lymphocytic leukaemia, T-prolymphocytic leukaemia or mantle cell lymphoma.
Br J Haematol
; 182(3): 429-433, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28643365
9.
SF3B1 hotspot mutations confer sensitivity to PARP inhibition by eliciting a defective replication stress response.
Nat Genet
; 55(8): 1311-1323, 2023 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37524790
10.
The PARP inhibitor olaparib induces significant killing of ATM-deficient lymphoid tumor cells in vitro and in vivo.
Blood
; 116(22): 4578-87, 2010 Nov 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-20739657
11.
Persistence of apoptotic cells without autoimmune disease or inflammation in CD14-/- mice.
J Cell Biol
; 167(6): 1161-70, 2004 Dec 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-15611337
12.
Developmental changes in the response of murine cerebellar granule cells to nitric oxide.
Neurochem Int
; 52(8): 1394-401, 2008 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-18406496
13.
Neurotrophic effects of leptin on cerebellar Purkinje but not granule neurons in vitro.
Neurosci Lett
; 438(1): 17-21, 2008 Jun 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-18472337
14.
Neurotoxic effects of homocysteine on cerebellar Purkinje neurons in vitro.
Neurosci Lett
; 413(1): 52-7, 2007 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-17157438
15.
Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts.
Oncotarget
; 8(27): 44749-44760, 2017 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28496009
16.
NK cell function is markedly impaired in patients with chronic lymphocytic leukaemia but is preserved in patients with small lymphocytic lymphoma.
Oncotarget
; 7(42): 68513-68526, 2016 Oct 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-27655680
17.
Embryonic cerebellar granule cells are resistant to necrosis induced by homocysteine.
Brain Res Dev Brain Res
; 160(1): 85-9, 2005 Nov 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-16154637
18.
T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice.
Dis Model Mech
; 8(11): 1401-12, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26398941
19.
PALB2 variant status in hematological malignancies - a potential therapeutic target?
Leuk Lymphoma
; 60(7): 1823-1826, 2019 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30614742
20.
Effects of nitric oxide on the survival and neuritogenesis of cerebellar Purkinje neurons.
J Mol Neurosci
; 46(2): 336-42, 2012 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-21728061