Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

An inducible Cldn11-CreER^T2 mouse line for selective targeting of lymphatic valves.

Ortsäter, Henrik; Hernández-Vásquez, Magda N; Ulvmar, Maria H; Gow, Alexander; Mäkinen, Taija.

Genesis ; 59(7-8): e23439, 2021 08.

Artigo em Inglês | MEDLINE | ID: mdl-34338433

2.

Combined transcriptome and proteome profiling of the pancreatic ß-cell response to palmitate unveils key pathways of ß-cell lipotoxicity.

Lytrivi, Maria; Ghaddar, Kassem; Lopes, Miguel; Rosengren, Victoria; Piron, Anthony; Yi, Xiaoyan; Johansson, Henrik; Lehtiö, Janne; Igoillo-Esteve, Mariana; Cunha, Daniel A; Marselli, Lorella; Marchetti, Piero; Ortsäter, Henrik; Eizirik, Decio L; Cnop, Miriam.

BMC Genomics ; 21(1): 590, 2020 Aug 26.

Artigo em Inglês | MEDLINE | ID: mdl-32847508

3.

Smooth muscle cell recruitment to lymphatic vessels requires PDGFB and impacts vessel size but not identity.

Wang, Yixin; Jin, Yi; Mäe, Maarja Andaloussi; Zhang, Yang; Ortsäter, Henrik; Betsholtz, Christer; Mäkinen, Taija; Jakobsson, Lars.

Development ; 144(19): 3590-3601, 2017 10 01.

Artigo em Inglês | MEDLINE | ID: mdl-28851707

4.

Targeting VEGF-B as a novel treatment for insulin resistance and type 2 diabetes.

Hagberg, Carolina E; Mehlem, Annika; Falkevall, Annelie; Muhl, Lars; Fam, Barbara C; Ortsäter, Henrik; Scotney, Pierre; Nyqvist, Daniel; Samén, Erik; Lu, Li; Stone-Elander, Sharon; Proietto, Joseph; Andrikopoulos, Sofianos; Sjöholm, Ake; Nash, Andrew; Eriksson, Ulf.

Nature ; 490(7420): 426-30, 2012 Oct 18.

Artigo em Inglês | MEDLINE | ID: mdl-23023133

5.

Cathelicidins positively regulate pancreatic ß-cell functions.

Sun, Jia; Xu, Meng; Ortsäter, Henrik; Lundeberg, Erik; Juntti-Berggren, Lisa; Chen, Yong Q; Haeggström, Jesper Z; Gudmundsson, Gudmundur H; Diana, Julien; Agerberth, Birgitta.

FASEB J ; 30(2): 884-94, 2016 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-26527065

6.

Glucocorticoids suppress GLP-1 secretion: possible contribution to their diabetogenic effects.

Kappe, Camilla; Fransson, Liselotte; Wolbert, Petra; Ortsäter, Henrik.

Clin Sci (Lond) ; 129(5): 405-14, 2015 Sep.

Artigo em Inglês | MEDLINE | ID: mdl-25853863

7.

Inhibition of palmitate-induced GADD34 expression augments apoptosis in mouse insulinoma cells (MIN6).

Fransson, Liselotte; Sjöholm, Ake; Ortsäter, Henrik.

Cell Biochem Funct ; 32(5): 445-52, 2014 Jul.

Artigo em Inglês | MEDLINE | ID: mdl-24633916

8.

Penile cavernous sinusoids are Prox1-positive hybrid vessels.

Schnabellehner, Sarah; Kraft, Marle; Schoofs, Hans; Ortsäter, Henrik; Mäkinen, Taija.

Vasc Biol ; 6(1)2024 Jan 01.

Artigo em Inglês | MEDLINE | ID: mdl-38051669

9.

GalR3 activation promotes adult neural stem cell survival in response to a diabetic milieu.

Mansouri, Shiva; Barde, Swapnali; Ortsäter, Henrik; Eweida, Mohamed; Darsalia, Vladimer; Langel, Ulo; Sjöholm, Ake; Hökfelt, Tomas; Patrone, Cesare.

J Neurochem ; 127(2): 209-20, 2013 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-23927369

10.

Immune-interacting lymphatic endothelial subtype at capillary terminals drives lymphatic malformation.

Petkova, Milena; Kraft, Marle; Stritt, Simon; Martinez-Corral, Ines; Ortsäter, Henrik; Vanlandewijck, Michael; Jakic, Bojana; Baselga, Eulàlia; Castillo, Sandra D; Graupera, Mariona; Betsholtz, Christer; Mäkinen, Taija.

J Exp Med ; 220(4)2023 04 03.

Artigo em Inglês | MEDLINE | ID: mdl-36688917

11.

Disruption of serine/threonine protein phosphatase 5 (PP5:PPP5c) in mice reveals a novel role for PP5 in the regulation of ultraviolet light-induced phosphorylation of serine/threonine protein kinase Chk1 (CHEK1).

Amable, Lauren; Grankvist, Nina; Largen, Jason W; Ortsäter, Henrik; Sjöholm, Åke; Honkanen, Richard E.

J Biol Chem ; 286(47): 40413-22, 2011 Nov 25.

Artigo em Inglês | MEDLINE | ID: mdl-21921034

12.

Thapsigargin down-regulates protein levels of GRP78/BiP in INS-1E cells.

Rosengren, Victoria; Johansson, Henrik; Lehtiö, Janne; Fransson, Liselotte; Sjöholm, Ake; Ortsäter, Henrik.

J Cell Biochem ; 113(5): 1635-44, 2012 May.

Artigo em Inglês | MEDLINE | ID: mdl-22189689

13.

Pituitary adenylate cyclase-activating polypeptide counteracts the impaired adult neural stem cell viability induced by palmitate.

Mansouri, Shiva; Ortsäter, Henrik; Pintor Gallego, Otto; Darsalia, Vladimer; Sjöholm, Ake; Patrone, Cesare.

J Neurosci Res ; 90(4): 759-68, 2012 Apr.

Artigo em Inglês | MEDLINE | ID: mdl-22183970

14.

Glucagon-like peptide-1 receptor activation reduces ischaemic brain damage following stroke in Type 2 diabetic rats.

Darsalia, Vladimer; Mansouri, Shiva; Ortsäter, Henrik; Olverling, Anna; Nozadze, Nino; Kappe, Camilla; Iverfeldt, Kerstin; Tracy, Linda M; Grankvist, Nina; Sjöholm, Åke; Patrone, Cesare.

Clin Sci (Lond) ; 122(10): 473-83, 2012 May 01.

Artigo em Inglês | MEDLINE | ID: mdl-22150224

15.

Cdh5-lineage-independent origin of dermal lymphatics shown by temporally restricted lineage tracing.

Zhang, Yan; Ortsäter, Henrik; Martinez-Corral, Ines; Mäkinen, Taija.

Life Sci Alliance ; 5(11)2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35961777

16.

Arachidonic acid fights palmitate: new insights into fatty acid toxicity in ß-cells.

Ortsäter, Henrik.

Clin Sci (Lond) ; 120(5): 179-81, 2011 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-21044045

17.

Coadministration of sitagliptin or metformin has no major impact on the adverse metabolic outcomes induced by dexamethasone treatment in rats.

Figueiredo, Bryanne Silva; Ferreira, Francielle Batista D; Barbosa, Amanda Marreiro; Dos Santos, Cristiane; Ortsäter, Henrik; Rafacho, Alex.

Life Sci ; 286: 120026, 2021 Dec 01.

Artigo em Inglês | MEDLINE | ID: mdl-34627773

18.

EphrinB2-EphB4 signalling provides Rho-mediated homeostatic control of lymphatic endothelial cell junction integrity.

Frye, Maike; Stritt, Simon; Ortsäter, Henrik; Hernandez Vasquez, Magda; Kaakinen, Mika; Vicente, Andres; Wiseman, John; Eklund, Lauri; Martínez-Torrecuadrada, Jorge L; Vestweber, Dietmar; Mäkinen, Taija.

Elife ; 92020 09 08.

Artigo em Inglês | MEDLINE | ID: mdl-32897857

19.

Blockade of VEGF-C signaling inhibits lymphatic malformations driven by oncogenic PIK3CA mutation.

Martinez-Corral, Ines; Zhang, Yan; Petkova, Milena; Ortsäter, Henrik; Sjöberg, Sofie; Castillo, Sandra D; Brouillard, Pascal; Libbrecht, Louis; Saur, Dieter; Graupera, Mariona; Alitalo, Kari; Boon, Laurence; Vikkula, Miikka; Mäkinen, Taija.

Nat Commun ; 11(1): 2869, 2020 06 08.

Artigo em Inglês | MEDLINE | ID: mdl-32513927

20.

Proteomics in diabetes research.

Sundsten, Tea; Ortsäter, Henrik.

Mol Cell Endocrinol ; 297(1-2): 93-103, 2009 Jan 15.

Artigo em Inglês | MEDLINE | ID: mdl-18657591

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