Detalhe da pesquisa
1.
Neutron crystallography and quantum chemical analysis of bilin reductase PcyA mutants reveal substrate and catalytic residue protonation states.
J Biol Chem
; 299(1): 102763, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36463961
2.
Visualizing the protons in a metalloenzyme electron proton transfer pathway.
Proc Natl Acad Sci U S A
; 117(12): 6484-6490, 2020 03 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-32152099
3.
Dynamics of urinary and respiratory shedding of Severe acute respiratory syndrome virus 2 (SARS-CoV-2) RNA excludes urine as a relevant source of viral transmission.
Infection
; 50(3): 635-642, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-34716901
4.
Using neutron crystallography to elucidate the basis of selective inhibition of carbonic anhydrase by saccharin and a derivative.
J Struct Biol
; 205(2): 147-154, 2019 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30639924
5.
Neutron structures of the Helicobacter pylori 5'-methylthioadenosine nucleosidase highlight proton sharing and protonation states.
Proc Natl Acad Sci U S A
; 113(48): 13756-13761, 2016 11 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-27856757
6.
Direct determination of protonation states and visualization of hydrogen bonding in a glycoside hydrolase with neutron crystallography.
Proc Natl Acad Sci U S A
; 112(40): 12384-9, 2015 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-26392527
7.
Joint neutron crystallographic and NMR solution studies of Tyr residue ionization and hydrogen bonding: Implications for enzyme-mediated proton transfer.
Proc Natl Acad Sci U S A
; 112(18): 5673-8, 2015 May 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-25902526
8.
Influence of the penetration enhancer isopropyl myristate on stratum corneum lipid model membranes revealed by neutron diffraction and 2H NMR experiments.
Biochim Biophys Acta Biomembr
; 1859(5): 745-755, 2017 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-28132900
9.
Charges Shift Protonation: Neutron Diffraction Reveals that Aniline and 2-Aminopyridine Become Protonated Upon Binding to Trypsin.
Angew Chem Int Ed Engl
; 56(17): 4887-4890, 2017 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-28371253
10.
Neutron and X-ray crystal structures of a perdeuterated enzyme inhibitor complex reveal the catalytic proton network of the Toho-1 ß-lactamase for the acylation reaction.
J Biol Chem
; 288(7): 4715-22, 2013 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23255594
11.
Neutron diffraction studies towards deciphering the protonation state of catalytic residues in the bacterial KDN9P phosphatase.
Acta Crystallogr Sect F Struct Biol Cryst Commun
; 69(Pt 9): 1015-9, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23989152
12.
Neutron crystallographic analysis of the nucleotide-binding domain of Hsp72 in complex with ADP.
IUCrJ
; 9(Pt 5): 562-572, 2022 Sep 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36071806
13.
How a Fragment Draws Attention to Selectivity Discriminating Features between the Related Proteases Trypsin and Thrombin.
J Med Chem
; 64(3): 1611-1625, 2021 02 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33471524
14.
Direct Observation of the Protonation States in the Mutant Green Fluorescent Protein.
J Phys Chem Lett
; 11(2): 492-496, 2020 Jan 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31880458
15.
Heme peroxidase-Trapping intermediates by cryo neutron crystallography.
Methods Enzymol
; 634: 379-389, 2020.
Artigo
em Inglês
| MEDLINE | ID: mdl-32093841
16.
Nature of the bonding in metal-silane sigma-complexes.
Inorg Chem
; 48(4): 1588-98, 2009 Feb 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-19146446
17.
Structural and thermodynamic characterization of the binding of isoliquiritigenin to the first bromodomain of BRD4.
FEBS J
; 286(9): 1656-1667, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30565859
18.
Neutron crystallographic study of heterotrimeric glutamine amidotransferase CAB.
Acta Crystallogr F Struct Biol Commun
; 75(Pt 3): 193-196, 2019 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30839294
19.
A molecular mechanism for transthyretin amyloidogenesis.
Nat Commun
; 10(1): 925, 2019 02 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-30804345
20.
Hydration Structures of the Human Protein Kinase CK2α Clarified by Joint Neutron and X-ray Crystallography.
J Mol Biol
; 430(24): 5094-5104, 2018 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30359582