Detalhe da pesquisa
1.
Novel Hydrazono-2-Iminothiazolidin-4-Ones Based on a Monoterpenic Skeleton as Potential Antitumor Agents: Synthesis, DFT Studies, inâ Vitro Cytotoxicity, Apoptosis Inducing Properties and Molecular Docking.
Chem Biodivers
; 19(7): e202100836, 2022 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-35665594
2.
Novel isoxazoline-linked 1,3,4-thiadiazole hybrids as anticancer agents: Design, synthesis, biological evaluation, molecular docking, and molecular dynamics simulation.
Arch Pharm (Weinheim)
; 355(9): e2200066, 2022 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-35594031
3.
Synthesis, characterization, molecular docking, and anticancer activities of new 1,3,4-oxadiazole-5-fluorocytosine hybrid derivatives.
J Mol Struct
; : 134135, 2022 Sep 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-36101881
4.
New 1,2,3-Triazoles from (R)-Carvone: Synthesis, DFT Mechanistic Study and In Vitro Cytotoxic Evaluation.
Molecules
; 27(3)2022 Jan 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35164037
5.
Design, synthesis, biological evaluation and molecular docking of new 1,3,4-oxadiazole homonucleosides and their double-headed analogs as antitumor agents.
Bioorg Chem
; 108: 104558, 2021 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-33358270
6.
Design, Hemiysnthesis, crystal structure and anticancer activity of 1, 2, 3-triazoles derivatives of totarol.
Bioorg Chem
; 115: 105165, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34298240
7.
Thiazolidinone-linked1,2,3-triazoles with monoterpenic skeleton as new potential anticancer agents: Design, synthesis and molecular docking studies.
Bioorg Chem
; 115: 105184, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34333421
8.
Discovery of novel furo[2,3-d]pyrimidin-2-one-1,3,4-oxadiazole hybrid derivatives as dual antiviral and anticancer agents that induce apoptosis.
Arch Pharm (Weinheim)
; 354(10): e2100146, 2021 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-34128255
9.
Design, synthesis, biological evaluation and molecular docking of new uracil analogs-1,2,4-oxadiazole hybrids as potential anticancer agents.
Bioorg Med Chem Lett
; 30(19): 127438, 2020 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32736079
10.
Unveiling the Different Chemical Reactivity of Diphenyl Nitrilimine and Phenyl Nitrile Oxide in [3+2] Cycloaddition Reactions with (R)-Carvone through the Molecular Electron Density Theory.
Molecules
; 25(5)2020 Feb 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-32121114
11.
Chemical profiling, cytotoxic activities through apoptosis induction in human fibrosarcoma and carcinoma cells, and molecular docking of some 1,2,3-triazole-isoxazoline hybrids using the eugenol as a precursors.
J Biomol Struct Dyn
; 41(7): 2759-2771, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35174765
12.
Cytotoxic and apoptotic effects of some (R)-carvone-isoxazoline derivatives on human fibrosarcoma and carcinoma cells: experimental evaluation for cytotoxicity, molecular docking and molecular dynamics studies.
J Biomol Struct Dyn
; 41(5): 1930-1943, 2023 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-35014592
13.
Hybrids of thiazolidinone with 1,2,3-triazole derivatives: design, synthesis, biological evaluation, in silico studies, molecular docking, molecular dynamics simulations, and ADMET profiling.
J Biomol Struct Dyn
; 41(21): 11987-11999, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36617941
14.
Discovery of a new Bcl-2 inhibitor through synthesis, anticancer activity, docking and MD simulations.
J Biomol Struct Dyn
; : 1-10, 2023 May 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-37255018
15.
New (S)-verbenone-isoxazoline-1,3,4-thiadiazole hybrids: synthesis, anticancer activity and apoptosis-inducing effect.
Future Med Chem
; 15(17): 1603-1619, 2023 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-37772541
16.
New 1,3,4-thiadiazoles derivatives: synthesis, antiproliferative activity, molecular docking and molecular dynamics.
Future Med Chem
; 14(12): 881-897, 2022 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35670219
17.
Crystal structure, Hirshfeld surface analysis and DFT calculations of (E)-3-[1-(2-hy-droxy-phenyl-anilino)ethyl-idene]-6-methyl-pyran-2,4-dione.
Acta Crystallogr E Crystallogr Commun
; 78(Pt 8): 864-870, 2022 Aug 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35974825
18.
New bis-isoxazole with monoterpenic skeleton: regioselective synthesis, spectroscopic investigation, electrochemical, and density functional theory (DFT) studies.
Turk J Chem
; 46(2): 506-522, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-38143458
19.
Design, synthesis, evaluation of new 3-acetylisoxazolines and their hybrid analogous as anticancer agents: In vitro and in silico analysis.
Comput Biol Chem
; 98: 107666, 2022 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-35381466
20.
Newly synthesized (R)-carvone-derived 1,2,3-triazoles: structural, mechanistic, cytotoxic and molecular docking studies.
J Biomol Struct Dyn
; 40(16): 7205-7217, 2022 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33719863