Detalhe da pesquisa
1.
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Proc Natl Acad Sci U S A
; 117(49): 31365-31375, 2020 12 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33229545
2.
Infection of Aedes albopictus Mosquito C6/36 Cells with the wMelpop Strain of Wolbachia Modulates Dengue Virus-Induced Host Cellular Transcripts and Induces Critical Sequence Alterations in the Dengue Viral Genome.
J Virol
; 93(15)2019 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31092581
3.
Serotype-specific interactions among functional domains of dengue virus 2 nonstructural proteins (NS) 5 and NS3 are crucial for viral RNA replication.
J Biol Chem
; 292(23): 9465-9479, 2017 06 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-28396347
4.
Dengue Virus Nonstructural Protein 5 (NS5) Assembles into a Dimer with a Unique Methyltransferase and Polymerase Interface.
PLoS Pathog
; 12(2): e1005451, 2016 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-26895240
5.
RNA helicase A activity is inhibited by oncogenic transcription factor EWS-FLI1.
Nucleic Acids Res
; 43(2): 1069-80, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25564528
6.
Flavivirus RNA synthesis in vitro.
Methods
; 91: 20-34, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26272247
7.
Substitution of NS5 N-terminal domain of dengue virus type 2 RNA with type 4 domain caused impaired replication and emergence of adaptive mutants with enhanced fitness.
J Biol Chem
; 289(32): 22385-400, 2014 Aug 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-24904061
8.
Structural complexity of Dengue virus untranslated regions: cis-acting RNA motifs and pseudoknot interactions modulating functionality of the viral genome.
Nucleic Acids Res
; 41(9): 5075-89, 2013 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-23531545
9.
Design, synthesis and characterization of novel 1,2-benzisothiazol-3(2H)-one and 1,3,4-oxadiazole hybrid derivatives: potent inhibitors of Dengue and West Nile virus NS2B/NS3 proteases.
Bioorg Med Chem
; 21(1): 102-13, 2013 Jan 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23211969
10.
Flavivirus proteases: The viral Achilles heel to prevent future pandemics.
Antiviral Res
; 210: 105516, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36586467
11.
Identification of cis-acting elements in the 3'-untranslated region of the dengue virus type 2 RNA that modulate translation and replication.
J Biol Chem
; 286(25): 22521-34, 2011 Jun 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-21515677
12.
Structures of flavivirus RNA promoters suggest two binding modes with NS5 polymerase.
Nat Commun
; 12(1): 2530, 2021 05 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33953197
13.
Host gene expression modulated by Zika virus infection of human-293 cells.
Virology
; 552: 32-42, 2021 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-33059318
14.
Genome 3'-end repair in dengue virus type 2.
RNA
; 14(12): 2645-56, 2008 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-18974278
15.
Inhibition of dengue virus by curcuminoids.
Antiviral Res
; 162: 71-78, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30529358
16.
Antiviral activities of selected antimalarials against dengue virus type 2 and Zika virus.
Antiviral Res
; 137: 141-150, 2017 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27889529
17.
High-throughput screening for the identification of small-molecule inhibitors of the flaviviral protease.
Antiviral Res
; 134: 6-16, 2016 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-27539384
18.
Flaviviral Replication Complex: Coordination between RNA Synthesis and 5'-RNA Capping.
Viruses
; 7(8): 4640-56, 2015 Aug 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-26287232
19.
Targeted mutagenesis of dengue virus type 2 replicon RNA by yeast in vivo recombination.
Methods Mol Biol
; 1138: 151-60, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24696336
20.
Construction of plasmid, bacterial expression, purification, and assay of dengue virus type 2 NS5 methyltransferase.
Methods Mol Biol
; 1138: 361-73, 2014.
Artigo
em Inglês
| MEDLINE | ID: mdl-24696348