RESUMO
This paper describes the pathogenesis, aetiology, epidemiology and the historical emergence of diverticular disease as a clinical problem. The symptoms of the uncomplicated disease can be treated successfully and cheapli with a high fibre diet including miller's bran. The method of giving bran and its results are described. The adoption of a high fibre diet lessens the need for surgery in diverticulitis and the author believes that it could prevent the appearance of the condition in future generations.
Assuntos
Celulose/uso terapêutico , Fibras na Dieta/uso terapêutico , Divertículo do Colo/dietoterapia , Idoso , Constipação Intestinal/complicações , Defecação , Divertículo do Colo/etiologia , Fezes , Preferências Alimentares , Humanos , Pessoa de Meia-IdadeAssuntos
Colo/patologia , Doença Diverticular do Colo , Divertículo do Colo , Adulto , Fatores Etários , Idoso , Colectomia , Colo/irrigação sanguínea , Colo/efeitos dos fármacos , Colo/fisiopatologia , Colo Sigmoide/fisiopatologia , Dieta/efeitos adversos , Divertículo do Colo/complicações , Divertículo do Colo/diagnóstico , Divertículo do Colo/etiologia , Divertículo do Colo/patologia , Divertículo do Colo/fisiopatologia , Divertículo do Colo/cirurgia , Divertículo do Colo/terapia , Feminino , Humanos , Fístula Intestinal/etiologia , Masculino , Meperidina/farmacologia , Pessoa de Meia-Idade , Morfina/farmacologia , Neostigmina/farmacologia , Parassimpatolíticos/uso terapêutico , Peritonite/etiologia , Pressão , Propantelina/uso terapêutico , Compostos de Amônio Quaternário/uso terapêutico , Fatores Sexuais , Xantenos/uso terapêuticoRESUMO
Diverticular disease of the colon is a new disease that appeared at the beginning of this century. It is now the commonest disease of the colon in the Western world, being found in 1 in 3 people of over 60 years of age. The pathogenesis of the disease involves excessive segmentation, but this does not explain its aetiology. The historical appearance of the disease on the clinical scene and its geographical distribution suggest that it is due to the removal of fibre from carbohydrates. The author treated 70 patients with symptomatic diverticular disease with a high-fibre diet. The results of this and the effects of bran are discussed.
Assuntos
Fibras na Dieta/uso terapêutico , Divertículo do Colo/etiologia , Negro ou Afro-Americano , População Negra , Colo/ultraestrutura , Defecação , Dieta , Divertículo do Colo/dietoterapia , Divertículo do Colo/epidemiologia , Humanos , África do Sul , Terminologia como Assunto , Fatores de Tempo , Uganda , População BrancaRESUMO
Sterculia with and without a smooth-muscle relaxant (alverine citrate) had similar beneficial effects on constipation and reduced the transit times in diverticular disease. Intracolonic pressure, however, varied with the preparation used. Though both preparations relieved the symptoms of diverticular disease, the one containing alverine citrate was more effective. Part of the mode of action of bran may be to relax the smooth muscle of the gut, since its actions were more comparable to those of sterculia plus alverine citrate than to those of sterculia alone.
Assuntos
Doença Diverticular do Colo/tratamento farmacológico , Parassimpatolíticos/uso terapêutico , Extratos Vegetais/uso terapêutico , Propilaminas/uso terapêutico , Resinas Vegetais/uso terapêutico , Ensaios Clínicos como Assunto , Colo/efeitos dos fármacos , Constipação Intestinal/tratamento farmacológico , Doença Diverticular do Colo/dietoterapia , Grão Comestível , Motilidade Gastrointestinal/efeitos dos fármacos , Humanos , Músculo Liso/efeitos dos fármacos , PressãoRESUMO
Seventy patients with diverticular disease of the colon were treated with a high-residue, low-sugar diet including unprocessed bran. Follow-up for an average of 22 months showed marked relief of symptoms in 62 patients. Bowel habit was restored towards normal and abdominal discomfort relieved. Only seven patients were unable to give up the use of laxatives. Eight patients did not tolerate the bran diet, and one of these needed surgical treatment. None of the 62 patients who took the diet needed surgery.