Detalhe da pesquisa
1.
Synergistic Nanomedicine Delivering Topoisomerase I Toxin (SN-38) and Inhibitors of Polynucleotide Kinase 3'-Phosphatase (PNKP) for Enhanced Treatment of Colorectal Cancer.
Mol Pharm
; 2024 May 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-38785196
2.
Unraveling the Silent Hydrolysis of Cyclic B-X/CâC Isosteres: The Striking Impact of a Single Heteroatom on the Aromatic, Acidic, and Dynamic Properties of Hemiboronic Phenanthroids.
J Am Chem Soc
; 144(23): 10570-10581, 2022 06 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647809
3.
Biodistribution and Activity of EGFR Targeted Polymeric Micelles Delivering a New Inhibitor of DNA Repair to Orthotopic Colorectal Cancer Xenografts with Metastasis.
Mol Pharm
; 19(6): 1825-1838, 2022 06 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35271294
4.
Lewis or Brønsted? A Rectification of the Acidic and Aromatic Nature of Boranol-Containing Naphthoid Heterocycles.
J Am Chem Soc
; 143(27): 10143-10156, 2021 07 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-34165966
5.
Diazaboryl-naphthyl-ketone: A New Scaffold with Bright Fluorescence, Aggregation-Induced Emission, and Application in the Quantitation of Trace Boronic Acids in Drug Intermediates.
Chemistry
; 26(63): 14324-14329, 2020 Nov 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-32681577
6.
Nano-Delivery of a Novel Inhibitor of Polynucleotide Kinase/Phosphatase (PNKP) for Targeted Sensitization of Colorectal Cancer to Radiation-Induced DNA Damage.
Front Oncol
; 11: 772920, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-35004293
7.
A synthetically lethal nanomedicine delivering novel inhibitors of polynucleotide kinase 3'-phosphatase (PNKP) for targeted therapy of PTEN-deficient colorectal cancer.
J Control Release
; 334: 335-352, 2021 06 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933518
8.
Total Synthesis of (+)-3-Demethoxyerythratidinone and (+)-Erysotramidine via the Oxidative Amidation of a Phenol.
Org Lett
; 17(14): 3422-5, 2015 Jul 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-26125652