Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Tissue CD14⁺CD8⁺ T cells reprogrammed by myeloid cells and modulated by LPS.

Pallett, Laura J; Swadling, Leo; Diniz, Mariana; Maini, Alexander A; Schwabenland, Marius; Gasull, Adrià Dalmau; Davies, Jessica; Kucykowicz, Stephanie; Skelton, Jessica K; Thomas, Niclas; Schmidt, Nathalie M; Amin, Oliver E; Gill, Upkar S; Stegmann, Kerstin A; Burton, Alice R; Stephenson, Emily; Reynolds, Gary; Whelan, Matt; Sanchez, Jenifer; de Maeyer, Roel; Thakker, Clare; Suveizdyte, Kornelija; Uddin, Imran; Ortega-Prieto, Ana M; Grant, Charlotte; Froghi, Farid; Fusai, Giuseppe; Lens, Sabela; Pérez-Del-Pulgar, Sofia; Al-Akkad, Walid; Mazza, Giuseppe; Noursadeghi, Mahdad; Akbar, Arne; Kennedy, Patrick T F; Davidson, Brian R; Prinz, Marco; Chain, Benjamin M; Haniffa, Muzlifah; Gilroy, Derek W; Dorner, Marcus; Bengsch, Bertram; Schurich, Anna; Maini, Mala K.

Nature ; 614(7947): 334-342, 2023 02.

Artigo em Inglês | MEDLINE | ID: mdl-36697826

2.

Researcher parents are paying a high price for conference travel - here's how to fix it.

Carter, Laura; Wolz, Laura; Pallett, Laura J.

Nature ; 630(8016): 517-518, 2024 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-38858485

3.

The human liver microenvironment shapes the homing and function of CD4⁺ T-cell populations.

Wiggins, Benjamin G; Pallett, Laura J; Li, Xiaoyan; Davies, Scott P; Amin, Oliver E; Gill, Upkar S; Kucykowicz, Stephanie; Patel, Arzoo M; Aliazis, Konstantinos; Liu, Yuxin S; Reynolds, Gary M; Davidson, Brian R; Gander, Amir; Luong, Tu Vinh; Hirschfield, Gideon M; Kennedy, Patrick T F; Huang, Yuehua; Maini, Mala K; Stamataki, Zania.

Gut ; 71(7): 1399-1411, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-34548339

4.

Therapeutic Potential of TLR8 Agonist GS-9688 (Selgantolimod) in Chronic Hepatitis B: Remodeling of Antiviral and Regulatory Mediators.

Amin, Oliver E; Colbeck, Emily J; Daffis, Stephane; Khan, Shahzada; Ramakrishnan, Dhivya; Pattabiraman, Divya; Chu, Ruth; Micolochick Steuer, Holly; Lehar, Sophie; Peiser, Leanne; Palazzo, Adam; Frey, Christian; Davies, Jessica; Javanbakht, Hassan; Rosenberg, William M C; Fletcher, Simon P; Maini, Mala K; Pallett, Laura J.

Hepatology ; 74(1): 55-71, 2021 07.

Artigo em Inglês | MEDLINE | ID: mdl-33368377

5.

Viral and immune factors associated with successful treatment withdrawal in HBeAg-negative chronic hepatitis B patients.

García-López, Mireia; Lens, Sabela; Pallett, Laura J; Testoni, Barbara; Rodríguez-Tajes, Sergio; Mariño, Zoe; Bartres, Concepción; García-Pras, Ester; Leonel, Thais; Perpiñán, Elena; Lozano, Juan José; Rodríguez-Frías, Francisco; Koutsoudakis, George; Zoulim, Fabien; Maini, Mala K; Forns, Xavier; Pérez-Del-Pulgar, Sofía.

J Hepatol ; 74(5): 1064-1074, 2021 05.

Artigo em Inglês | MEDLINE | ID: mdl-33278456

6.

Immunological fortification at our barrier organs: Protecting us as we age.

Harker, James A; Pallett, Laura J.

Immunology ; 160(2): 103-105, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32400027

7.

Fine needle aspirates comprehensively sample intrahepatic immunity.

Gill, Upkar S; Pallett, Laura J; Thomas, Niclas; Burton, Alice R; Patel, Amit A; Yona, Simon; Kennedy, Patrick T F; Maini, Mala K.

Gut ; 68(8): 1493-1503, 2019 08.

Artigo em Inglês | MEDLINE | ID: mdl-30487267

8.

Liver sampling: a vital window into HBV pathogenesis on the path to functional cure.

Gill, Upkar S; Pallett, Laura J; Kennedy, Patrick T F; Maini, Mala K.

Gut ; 67(4): 767-775, 2018 04.

Artigo em Inglês | MEDLINE | ID: mdl-29331944

9.

Eomeshi NK Cells in Human Liver Are Long-Lived and Do Not Recirculate but Can Be Replenished from the Circulation.

Cuff, Antonia O; Robertson, Francis P; Stegmann, Kerstin A; Pallett, Laura J; Maini, Mala K; Davidson, Brian R; Male, Victoria.

J Immunol ; 197(11): 4283-4291, 2016 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-27798170

10.

IL-2 leaves its mark in cirrhosis.

Burton, Alice R; Pallett, Laura J.

J Hepatol ; 74(3): 505-507, 2021 03.

Artigo em Inglês | MEDLINE | ID: mdl-33422337

11.

Liver-resident CD8+ T cells: Learning lessons from the local experts.

Swadling, Leo; Pallett, Laura J; Maini, Mala K.

J Hepatol ; 72(6): 1049-1051, 2020 06.

Artigo em Inglês | MEDLINE | ID: mdl-32122722

12.

The third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cells.

Schurich, Anna; Pallett, Laura J; Lubowiecki, Marcin; Singh, Harsimran D; Gill, Upkar S; Kennedy, Patrick T; Nastouli, Eleni; Tanwar, Sudeep; Rosenberg, William; Maini, Mala K.

PLoS Pathog ; 9(3): e1003208, 2013 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-23516358

13.

Pro-fibrogenic role of alarmin high mobility group box 1 in HIV-hepatitis B virus coinfection.

Singh, Kasha P; Pallett, Laura J; Singh, Harsimran; Chen, Antony; Otano, Itziar; Duriez, Marion; Rombouts, Krista; Pinzani, Massimo; Crane, Megan; Fusai, Giuseppe; Avihingsanon, Anchalee; Lewin, Sharon R; Maini, Mala K.

AIDS ; 37(3): 401-411, 2023 03 01.

Artigo em Inglês | MEDLINE | ID: mdl-36384811

14.

Human resident liver myeloid cells protect against metabolic stress in obesity.

Barreby, Emelie; Strunz, Benedikt; Nock, Sebastian; Naudet, Léa; Shen, Joanne X; Johansson, Helene; Sönnerborg, Isabella; Ma, Junjie; Urgard, Egon; Pallett, Laura J; Hu, Yizhou; Fardellas, Achilleas; Azzimato, Valerio; Vankova, Ana; Levi, Laura; Morgantini, Cecilia; Maini, Mala K; Stål, Per; Rosshart, Stephan P; Coquet, Jonathan M; Nowak, Greg; Näslund, Erik; Lauschke, Volker M; Ellis, Ewa; Björkström, Niklas K; Chen, Ping; Aouadi, Myriam.

Nat Metab ; 5(7): 1188-1203, 2023 07.

Artigo em Inglês | MEDLINE | ID: mdl-37414931

15.

Liver-resident memory T cells: life in lockdown.

Pallett, Laura J; Maini, Mala K.

Semin Immunopathol ; 44(6): 813-825, 2022 11.

Artigo em Inglês | MEDLINE | ID: mdl-35482059

16.

Isolation of human intrahepatic leukocytes for phenotypic and functional characterization by flow cytometry.

Kucykowicz, Stephanie; Amin, Oliver E; Burton, Alice R; Swadling, Leo; Schmidt, Nathalie M; Zakeri, Nekisa; Davies, Jessica; Aidoo-Micah, Gloryanne; Stegmann, Kerstin A; Easom, Nicholas J; Jeffery-Smith, Anna; Maini, Mala K; Pallett, Laura J.

STAR Protoc ; 3(2): 101356, 2022 06 17.

Artigo em Inglês | MEDLINE | ID: mdl-35516846

17.

Characterisation and induction of tissue-resident gamma delta T-cells to target hepatocellular carcinoma.

Zakeri, Nekisa; Hall, Andrew; Swadling, Leo; Pallett, Laura J; Schmidt, Nathalie M; Diniz, Mariana O; Kucykowicz, Stephanie; Amin, Oliver E; Gander, Amir; Pinzani, Massimo; Davidson, Brian R; Quaglia, Alberto; Maini, Mala K.

Nat Commun ; 13(1): 1372, 2022 03 16.

Artigo em Inglês | MEDLINE | ID: mdl-35296658

18.

HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells.

Reuschl, Ann-Kathrin; Mesner, Dejan; Shivkumar, Maitreyi; Whelan, Matthew V X; Pallett, Laura J; Guerra-Assunção, José Afonso; Madansein, Rajhmun; Dullabh, Kaylesh J; Sigal, Alex; Thornhill, John P; Herrera, Carolina; Fidler, Sarah; Noursadeghi, Mahdad; Maini, Mala K; Jolly, Clare.

Cell Rep ; 39(2): 110650, 2022 04 12.

Artigo em Inglês | MEDLINE | ID: mdl-35417711

19.

A glutamine 'tug-of-war': targets to manipulate glutamine metabolism for cancer immunotherapy.

Pallett, Laura J; Dimeloe, Sarah; Sinclair, Linda V; Byrne, Adam J; Schurich, Anna.

Immunother Adv ; 1(1): ltab010, 2021 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-34541580

20.

Irreversible Electroporation (IRE) in Locally Advanced Pancreatic Cancer: A Review of Current Clinical Outcomes, Mechanism of Action and Opportunities for Synergistic Therapy.

Rai, Zainab L; Feakins, Roger; Pallett, Laura J; Manas, Derek; Davidson, Brian R.

J Clin Med ; 10(8)2021 Apr 10.

Artigo em Inglês | MEDLINE | ID: mdl-33920118

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