Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Multiphase coalescence mediates Hippo pathway activation.

Wang, Li; Choi, Kyungsuk; Su, Ting; Li, Bing; Wu, Xiaofeng; Zhang, Ruihui; Driskill, Jordan H; Li, Hongde; Lei, Huiyan; Guo, Pengfei; Chen, Elizabeth H; Zheng, Yonggang; Pan, Duojia.

Cell ; 185(23): 4376-4393.e18, 2022 11 10.

Artigo em Inglês | MEDLINE | ID: mdl-36318920

2.

Control of stem cell renewal and fate by YAP and TAZ.

Driskill, Jordan H; Pan, Duojia.

Nat Rev Mol Cell Biol ; 24(12): 895-911, 2023 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-37626124

3.

Toll Receptor-Mediated Hippo Signaling Controls Innate Immunity in Drosophila.

Liu, Bo; Zheng, Yonggang; Yin, Feng; Yu, Jianzhong; Silverman, Neal; Pan, Duojia.

Cell ; 164(3): 406-19, 2016 Jan 28.

Artigo em Inglês | MEDLINE | ID: mdl-26824654

4.

YAP-VGLL4 antagonism defines the major physiological function of the Hippo signaling effector YAP.

Cai, Jing; Choi, Kyungsuk; Li, Hongde; Pulgar Prieto, Katiuska Daniela; Zheng, Yonggang; Pan, Duojia.

Genes Dev ; 36(21-24): 1119-1128, 2022.

Artigo em Inglês | MEDLINE | ID: mdl-36522128

5.

WWTR1(TAZ)-CAMTA1 reprograms endothelial cells to drive epithelioid hemangioendothelioma.

Driskill, Jordan H; Zheng, Yonggang; Wu, Bo-Kuan; Wang, Li; Cai, Jing; Rakheja, Dinesh; Dellinger, Michael; Pan, Duojia.

Genes Dev ; 35(7-8): 495-511, 2021 04 01.

Artigo em Inglês | MEDLINE | ID: mdl-33766984

6.

Assembling a Hippo: the evolutionary emergence of an animal developmental signaling pathway.

Phillips, Jonathan E; Zheng, Yonggang; Pan, Duojia.

Trends Biochem Sci ; 2024 May 09.

Artigo em Inglês | MEDLINE | ID: mdl-38729842

7.

Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2.

Yin, Feng; Yu, Jianzhong; Zheng, Yonggang; Chen, Qian; Zhang, Nailing; Pan, Duojia.

Cell ; 154(6): 1342-55, 2013 Sep 12.

Artigo em Inglês | MEDLINE | ID: mdl-24012335

8.

A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease.

Cai, Jing; Song, Xuewen; Wang, Wei; Watnick, Terry; Pei, York; Qian, Feng; Pan, Duojia.

Genes Dev ; 32(11-12): 781-793, 2018 06 01.

Artigo em Inglês | MEDLINE | ID: mdl-29891559

9.

Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.

Alarcón, Claudio; Zaromytidou, Alexia-Ileana; Xi, Qiaoran; Gao, Sheng; Yu, Jianzhong; Fujisawa, Sho; Barlas, Afsar; Miller, Alexandria N; Manova-Todorova, Katia; Macias, Maria J; Sapkota, Gopal; Pan, Duojia; Massagué, Joan.

Cell ; 139(4): 757-69, 2009 Nov 13.

Artigo em Inglês | MEDLINE | ID: mdl-19914168

10.

The unfolding of the Hippo signaling pathway.

Pan, Duojia.

Dev Biol ; 487: 1-9, 2022 07.

Artigo em Inglês | MEDLINE | ID: mdl-35405135

11.

ß-Catenin destruction complex-independent regulation of Hippo-YAP signaling by APC in intestinal tumorigenesis.

Cai, Jing; Maitra, Anirban; Anders, Robert A; Taketo, Makoto M; Pan, Duojia.

Genes Dev ; 29(14): 1493-506, 2015 Jul 15.

Artigo em Inglês | MEDLINE | ID: mdl-26193883

12.

Structural basis for Mob1-dependent activation of the core Mst-Lats kinase cascade in Hippo signaling.

Ni, Lisheng; Zheng, Yonggang; Hara, Mayuko; Pan, Duojia; Luo, Xuelian.

Genes Dev ; 29(13): 1416-31, 2015 Jul 01.

Artigo em Inglês | MEDLINE | ID: mdl-26108669

13.

Homeostatic control of Hippo signaling activity revealed by an endogenous activating mutation in YAP.

Chen, Qian; Zhang, Nailing; Xie, Rui; Wang, Wei; Cai, Jing; Choi, Kyung-Suk; David, Karen Kate; Huang, Bo; Yabuta, Norikazu; Nojima, Hiroshi; Anders, Robert A; Pan, Duojia.

Genes Dev ; 29(12): 1285-97, 2015 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-26109051

14.

A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis.

Moroishi, Toshiro; Park, Hyun Woo; Qin, Baodong; Chen, Qian; Meng, Zhipeng; Plouffe, Steven W; Taniguchi, Koji; Yu, Fa-Xing; Karin, Michael; Pan, Duojia; Guan, Kun-Liang.

Genes Dev ; 29(12): 1271-84, 2015 Jun 15.

Artigo em Inglês | MEDLINE | ID: mdl-26109050

15.

A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis.

Chen, Qian; Zhang, Nailing; Gray, Ryan S; Li, Huili; Ewald, Andrew J; Zahnow, Cynthia A; Pan, Duojia.

Genes Dev ; 28(5): 432-7, 2014 Mar 01.

Artigo em Inglês | MEDLINE | ID: mdl-24589775

16.

FADS3 is a Δ14Z sphingoid base desaturase that contributes to gender differences in the human plasma sphingolipidome.

Karsai, Gergely; Lone, Museer; Kutalik, Zoltán; Brenna, J Thomas; Li, Hongde; Pan, Duojia; von Eckardstein, Arnold; Hornemann, Thorsten.

J Biol Chem ; 295(7): 1889-1897, 2020 02 14.

Artigo em Inglês | MEDLINE | ID: mdl-31862735

17.

Validating upstream regulators of Yorkie activity in Hippo signaling through scalloped-based genetic epistasis.

Yu, Jianzhong; Pan, Duojia.

Development ; 145(4)2018 02 21.

Artigo em Inglês | MEDLINE | ID: mdl-29467233

18.

Protein kinase A activates the Hippo pathway to modulate cell proliferation and differentiation.

Yu, Fa-Xing; Zhang, Yifan; Park, Hyun Woo; Jewell, Jenna L; Chen, Qian; Deng, Yaoting; Pan, Duojia; Taylor, Susan S; Lai, Zhi-Chun; Guan, Kun-Liang.

Genes Dev ; 27(11): 1223-32, 2013 Jun 01.

Artigo em Inglês | MEDLINE | ID: mdl-23752589

19.

Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling.

Serafimidis, Ioannis; Rodriguez-Aznar, Eva; Lesche, Mathias; Yoshioka, Kazuaki; Takuwa, Yoh; Dahl, Andreas; Pan, Duojia; Gavalas, Anthony.

PLoS Biol ; 15(3): e2000949, 2017 03.

Artigo em Inglês | MEDLINE | ID: mdl-28248965

20.

YAP Controls Endothelial Activation and Vascular Inflammation Through TRAF6.

Lv, Yang; Kim, Kyungho; Sheng, Yue; Cho, Jaehyung; Qian, Zhijian; Zhao, You-Yang; Hu, Gang; Pan, Duojia; Malik, Asrar B; Hu, Guochang.

Circ Res ; 123(1): 43-56, 2018 06 22.

Artigo em Inglês | MEDLINE | ID: mdl-29794022

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