Detalhe da pesquisa
1.
Identification and characterization of a strong constitutive promoter stnYp for activating biosynthetic genes and producing natural products in streptomyces.
Microb Cell Fact
; 22(1): 127, 2023 Jul 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-37443029
2.
Characterization of Miharamycin Biosynthesis Reveals a Hybrid NRPS-PKS to Synthesize High-Carbon Sugar from a Complex Nucleoside.
J Am Chem Soc
; 142(13): 5996-6000, 2020 04 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32167762
3.
Activation and Characterization of Cryptic Gene Cluster: Two Series of Aromatic Polyketides Biosynthesized by Divergent Pathways.
Angew Chem Int Ed Engl
; 58(50): 18046-18054, 2019 12 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31553109
4.
Enzymatic Formation of Oxygen-Containing Heterocycles in Natural Product Biosynthesis.
Chembiochem
; 19(19): 2002-2022, 2018 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-30039582
5.
Directed production of aurantizolicin and new members based on a YM-216391 biosynthetic system.
Org Biomol Chem
; 16(48): 9373-9376, 2018 12 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-30516779
6.
A Six-Oxidase Cascade for Tandem C-H Bond Activation Revealed by Reconstitution of Bicyclomycin Biosynthesis.
Angew Chem Int Ed Engl
; 57(3): 719-723, 2018 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29194897
7.
Enzymology of Anthraquinone-γ-Pyrone Ring Formation in Complex Aromatic Polyketide Biosynthesis.
Angew Chem Int Ed Engl
; 57(41): 13475-13479, 2018 10 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30151879
8.
The SARP Family Regulator Txn9 and Two-Component Response Regulator Txn11 are Key Activators for Trioxacarcin Biosynthesis in Streptomyces bottropensis.
Curr Microbiol
; 71(4): 458-64, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26178900
9.
Production of a trioxacarcin analog by introducing a C-3 dehydratase into deoxysugar biosynthesis.
Acta Biochim Biophys Sin (Shanghai)
; 51(5): 539-541, 2019 May 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-30968938
10.
A Secreted BBE-Like Enzyme Acting as a Drug-Binding Efflux Carrier Confers Microbial Self-Resistance to Mitomycin C.
Org Lett
; 26(6): 1233-1237, 2024 02 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-38308850
11.
Genetic manipulation revealing an unusual N-terminal region in a stand-alone non-ribosomal peptide synthetase involved in the biosynthesis of ramoplanins.
Biotechnol Lett
; 35(1): 107-14, 2013 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-23007448
12.
Production of ramoplanin analogues by genetic engineering of Actinoplanes sp.
Biotechnol Lett
; 35(10): 1685-92, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23801115
13.
Functional identification of the gene encoding the enzyme involved in mannosylation in ramoplanin biosynthesis in Actinoplanes sp.
Biotechnol Lett
; 35(9): 1501-8, 2013 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-23892980
14.
Newly Discovered Mechanisms of Antibiotic Self-Resistance with Multiple Enzymes Acting at Different Locations and Stages.
Antibiotics (Basel)
; 12(1)2022 Dec 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36671236
15.
Production of doramectin by rational engineering of the avermectin biosynthetic pathway.
Bioorg Med Chem Lett
; 21(11): 3320-3, 2011 Jun 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-21514826
16.
Improvement of spinosad production by overexpression of gtt and gdh controlled by promoter PermE* in Saccharopolyspora spinosa SIPI-A2090.
Biotechnol Lett
; 33(4): 733-9, 2011 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-21107647
17.
Identification and Characterization of Enzymes Catalyzing Early Steps in Miharamycin and Amipurimycin Biosynthesis.
Org Lett
; 23(22): 8761-8765, 2021 11 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-34747180
18.
Identification of the Amipurimycin Gene Cluster Yields Insight into the Biosynthesis of C9 Sugar Nucleoside Antibiotics.
Org Lett
; 21(9): 3148-3152, 2019 05 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-30990701
19.
Elucidation of the Herbicidin Tailoring Pathway Offers Insights into Its Structural Diversity.
Org Lett
; 21(5): 1374-1378, 2019 03 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30763106
20.
New insights into bacterial type II polyketide biosynthesis.
F1000Res
; 6: 172, 2017.
Artigo
em Inglês
| MEDLINE | ID: mdl-28299197