Detalhe da pesquisa
1.
Unique pharmacodynamic properties and low abuse liability of the µ-opioid receptor ligand (S)-methadone.
Mol Psychiatry
; 2023 Dec 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-38145984
2.
The Leu/Val6.51 Side Chain of Cannabinoid Receptors Regulates the Binding Mode of the Alkyl Chain of Δ9-Tetrahydrocannabinol.
J Chem Inf Model
; 63(18): 5927-5935, 2023 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37644761
3.
Preferential Gs protein coupling of the galanin Gal1 receptor in the µ-opioid-Gal1 receptor heterotetramer.
Pharmacol Res
; 182: 106322, 2022 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35750299
4.
Pharmacological targeting of G protein-coupled receptor heteromers.
Pharmacol Res
; 185: 106476, 2022 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-36182040
5.
A Single Point Mutation Blocks the Entrance of Ligands to the Cannabinoid CB2 Receptor via the Lipid Bilayer.
J Chem Inf Model
; 62(22): 5771-5779, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36302505
6.
Structure and function of adenosine receptor heteromers.
Cell Mol Life Sci
; 78(8): 3957-3968, 2021 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-33580270
7.
The mutational landscape of human olfactory G protein-coupled receptors.
BMC Biol
; 19(1): 21, 2021 02 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-33546694
8.
Discovery of a macromolecular complex mediating the hunger suppressive actions of cocaine: Structural and functional properties.
Addict Biol
; 26(5): e13017, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-33559278
9.
Control of glutamate release by complexes of adenosine and cannabinoid receptors.
BMC Biol
; 18(1): 9, 2020 01 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-31973708
10.
Discovery of Homobivalent Bitopic Ligands of the Cannabinoid CB2 Receptor*.
Chemistry
; 26(68): 15839-15842, 2020 Dec 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-32794211
11.
The size matters? A computational tool to design bivalent ligands.
Bioinformatics
; 34(22): 3857-3863, 2018 11 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-29850769
12.
Identifying human diamine sensors for death related putrescine and cadaverine molecules.
PLoS Comput Biol
; 14(1): e1005945, 2018 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-29324768
13.
Mechanisms Underlying Allosteric Molecular Switches of Metabotropic Glutamate Receptor 5.
J Chem Inf Model
; 59(5): 2456-2466, 2019 05 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-30811196
14.
Cross-communication between Gi and Gs in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain.
BMC Biol
; 16(1): 24, 2018 02 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-29486745
15.
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors.
PLoS Biol
; 13(7): e1002194, 2015 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-26158621
16.
Crystal structure of the µ-opioid receptor bound to a morphinan antagonist.
Nature
; 485(7398): 321-6, 2012 Mar 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-22437502
17.
Development of a Nucleotide Exchange Inhibitor That Impairs Ras Oncogenic Signaling.
Chemistry
; 23(7): 1676-1685, 2017 Jan 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27885731
18.
Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with Gi and Gs.
BMC Biol
; 14: 26, 2016 Apr 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-27048449
19.
Ligand-specific regulation of the extracellular surface of a G-protein-coupled receptor.
Nature
; 463(7277): 108-12, 2010 Jan 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-20054398
20.
GPCRtm: An amino acid substitution matrix for the transmembrane region of class A G Protein-Coupled Receptors.
BMC Bioinformatics
; 16: 206, 2015 Jul 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-26134144