Detalhe da pesquisa
1.
Machine learning-based marker for coronary artery disease: derivation and validation in two longitudinal cohorts.
Lancet
; 401(10372): 215-225, 2023 Jan 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-36563696
2.
Discovery of a NAPE-PLD inhibitor that modulates emotional behavior in mice.
Nat Chem Biol
; 16(6): 667-675, 2020 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-32393901
3.
The Heterogeneity of Lipid Metabolism in Cancer.
Adv Exp Med Biol
; 1311: 39-56, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34014533
4.
Bleomycin Induces Drug Efflux in Lungs. A Pitfall for Pharmacological Studies of Pulmonary Fibrosis.
Am J Respir Cell Mol Biol
; 62(2): 178-190, 2020 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31419911
5.
Combination therapy with BPTES nanoparticles and metformin targets the metabolic heterogeneity of pancreatic cancer.
Proc Natl Acad Sci U S A
; 113(36): E5328-36, 2016 09 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27559084
6.
Network analyses identify liver-specific targets for treating liver diseases.
Mol Syst Biol
; 13(8): 938, 2017 08 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-28827398
7.
Cannabinoid-1 receptor deletion in podocytes mitigates both glomerular and tubular dysfunction in a mouse model of diabetic nephropathy.
Diabetes Obes Metab
; 20(3): 698-708, 2018 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-29106063
8.
The Heterogeneity of Lipid Metabolism in Cancer.
Adv Exp Med Biol
; 1063: 33-55, 2018.
Artigo
em Inglês
| MEDLINE | ID: mdl-29946774
9.
Genome-first evaluation with exome sequence and clinical data uncovers underdiagnosed genetic disorders in a large healthcare system.
Cell Rep Med
; 5(5): 101518, 2024 May 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38642551
10.
Muesli Intake May Protect Against Coronary Artery Disease: Mendelian Randomization on 13 Dietary Traits.
JACC Adv
; 3(4)2024 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-38737007
11.
Development of a human genetics-guided priority score for 19,365 genes and 399 drug indications.
Nat Genet
; 56(1): 51-59, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38172303
12.
An Integrative Multiomics Framework for Identification of Therapeutic Targets in Pulmonary Fibrosis.
Adv Sci (Weinh)
; 10(16): e2207454, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37038090
13.
Phenome-wide Mendelian randomization study of plasma triglyceride levels and 2600 disease traits.
Elife
; 122023 03 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-36988189
14.
A machine learning model identifies patients in need of autoimmune disease testing using electronic health records.
Nat Commun
; 14(1): 2385, 2023 04 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37169741
15.
In vitro and in vivo pharmacokinetic characterization, chiral conversion and PBPK scaling towards human PK simulation of S-MRI-1867, a drug candidate for Hermansky-Pudlak syndrome pulmonary fibrosis.
Biomed Pharmacother
; 168: 115178, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890204
16.
Peripheral Hybrid CB1R and iNOS Antagonist MRI-1867 Displays Anti-Fibrotic Efficacy in Bleomycin-Induced Skin Fibrosis.
Front Endocrinol (Lausanne)
; 12: 744857, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34650521
17.
CB1 R and iNOS are distinct players promoting pulmonary fibrosis in Hermansky-Pudlak syndrome.
Clin Transl Med
; 11(7): e471, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-34323400
18.
Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis.
Cell Metab
; 29(6): 1320-1333.e8, 2019 06 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31105045
19.
Machine Learning Identifies Plasma Metabolites Associated With Heart Failure in Underrepresented Populations With the TTR V122I Variant.
J Am Heart Assoc
; 12(8): e027736, 2023 04 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37042260
20.
Developmental Role of Macrophage Cannabinoid-1 Receptor Signaling in Type 2 Diabetes.
Diabetes
; 66(4): 994-1007, 2017 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-28082458