Detalhe da pesquisa
1.
Human anti-C1q autoantibodies bind specifically to solid-phase C1q and enhance phagocytosis but not complement activation.
Proc Natl Acad Sci U S A
; 120(50): e2310666120, 2023 Dec 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-38048459
2.
Molecular Basis of Assembly and Activation of Complement Component C1 in Complex with Immunoglobulin G1 and Antigen.
Mol Cell
; 63(1): 135-45, 2016 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-27320199
3.
Functional monovalency amplifies the pathogenicity of anti-MuSK IgG4 in myasthenia gravis.
Proc Natl Acad Sci U S A
; 118(13)2021 03 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-33753489
4.
C1q binding to surface-bound IgG is stabilized by C1r2s2 proteases.
Proc Natl Acad Sci U S A
; 118(26)2021 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-34155115
5.
Discovery of amivantamab (JNJ-61186372), a bispecific antibody targeting EGFR and MET.
J Biol Chem
; 296: 100641, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-33839159
6.
Unraveling the Macromolecular Pathways of IgG Oligomerization and Complement Activation on Antigenic Surfaces.
Nano Lett
; 19(7): 4787-4796, 2019 07 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31184907
7.
Monoclonal antibodies targeting CD38 in hematological malignancies and beyond.
Immunol Rev
; 270(1): 95-112, 2016 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-26864107
8.
CD20 and CD37 antibodies synergize to activate complement by Fc-mediated clustering.
Haematologica
; 104(9): 1841-1852, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-30792198
9.
A Novel Platform for the Potentiation of Therapeutic Antibodies Based on Antigen-Dependent Formation of IgG Hexamers at the Cell Surface.
PLoS Biol
; 14(1): e1002344, 2016 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-26736041
10.
Monoclonal Antibodies against Epidermal Growth Factor Receptor Acquire an Ability To Kill Tumor Cells through Complement Activation by Mutations That Selectively Facilitate the Hexamerization of IgG on Opsonized Cells.
J Immunol
; 198(4): 1585-1594, 2017 02 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-28062698
11.
The Therapeutic CD38 Monoclonal Antibody Daratumumab Induces Programmed Cell Death via Fcγ Receptor-Mediated Cross-Linking.
J Immunol
; 197(3): 807-13, 2016 08 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27316683
12.
Antibodies That Efficiently Form Hexamers upon Antigen Binding Can Induce Complement-Dependent Cytotoxicity under Complement-Limiting Conditions.
J Immunol
; 197(5): 1762-75, 2016 09 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-27474078
13.
Type I CD20 Antibodies Recruit the B Cell Receptor for Complement-Dependent Lysis of Malignant B Cells.
J Immunol
; 197(12): 4829-4837, 2016 12 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27807190
14.
Hexamerization-enhanced CD20 antibody mediates complement-dependent cytotoxicity in serum genetically deficient in C9.
Clin Immunol
; 181: 24-28, 2017 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-28578024
15.
Enhancing Accuracy in Molecular Weight Determination of Highly Heterogeneously Glycosylated Proteins by Native Tandem Mass Spectrometry.
Anal Chem
; 89(9): 4793-4797, 2017 05 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-28383250
16.
Cysteine-SILAC Mass Spectrometry Enabling the Identification and Quantitation of Scrambled Interchain Disulfide Bonds: Preservation of Native Heavy-Light Chain Pairing in Bispecific IgGs Generated by Controlled Fab-arm Exchange.
Anal Chem
; 89(20): 10873-10882, 2017 10 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-28922593
17.
Pre-clinical evaluation of CD38 chimeric antigen receptor engineered T cells for the treatment of multiple myeloma.
Haematologica
; 101(5): 616-25, 2016 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-26858358
18.
Efficient generation of stable bispecific IgG1 by controlled Fab-arm exchange.
Proc Natl Acad Sci U S A
; 110(13): 5145-50, 2013 Mar 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-23479652
19.
Tandem Native Mass-Spectrometry on Antibody-Drug Conjugates and Submillion Da Antibody-Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector.
Anal Chem
; 87(12): 6095-102, 2015 Jun 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-25978613
20.
Ibrutinib interferes with the cell-mediated anti-tumor activities of therapeutic CD20 antibodies: implications for combination therapy.
Haematologica
; 100(1): 77-86, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25344523