Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Venous and arterial thrombosis in patients with VEXAS syndrome.

Kusne, Yael; Ghorbanzadeh, Atefeh; Dulau-Florea, Alina; Shalhoub, Ruba; Alcedo, Pedro E; Nghiem, Khanh; Ferrada, Marcela A; Hines, Alexander; Quinn, Kaitlin A; Panicker, Sumith R; Ombrello, Amanda K; Reichard, Kaaren; Darden, Ivana; Goodspeed, Wendy; Durrani, Jibran; Wilson, Lorena; Olteanu, Horatiu; Lasho, Terra; Kastner, Daniel L; Warrington, Kenneth J; Mangaonkar, Abhishek; Go, Ronald S; Braylan, Raul C; Beck, David B; Patnaik, Mrinal M; Young, Neal S; Calvo, Katherine R; Casanegra, Ana I; Grayson, Peter C; Koster, Matthew J; Wu, Colin O; Kanthi, Yogendra; Patel, Bhavisha A; Houghton, Damon E; Groarke, Emma M.

Blood ; 143(21): 2190-2200, 2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38306657

2.

Efficacy of JAK1/2 inhibition in murine immune bone marrow failure.

Groarke, Emma M; Feng, Xingmin; Aggarwal, Nidhi; Manley, Ash Lee; Wu, Zhijie; Gao, Shouguo; Patel, Bhavisha A; Chen, Jichun; Young, Neal S.

Blood ; 141(1): 72-89, 2023 01 05.

Artigo em Inglês | MEDLINE | ID: mdl-36130301

3.

Differential diagnosis of bone marrow failure syndromes guided by machine learning.

Gutierrez-Rodrigues, Fernanda; Munger, Eric; Ma, Xiaoyang; Groarke, Emma M; Tang, Youbao; Patel, Bhavisha A; Catto, Luiz Fernando B; Clé, Diego V; Niewisch, Marena R; Alves-Paiva, Raquel M; Donaires, Flávia S; Pinto, André Luiz; Borges, Gustavo; Santana, Barbara A; McReynolds, Lisa J; Giri, Neelam; Altintas, Burak; Fan, Xing; Shalhoub, Ruba; Siwy, Christopher M; Diamond, Carrie; Raffo, Diego Quinones; Craft, Kathleen; Kajigaya, Sachiko; Summers, Ronald M; Liu, Paul; Cunningham, Lea; Hickstein, Dennis D; Dunbar, Cynthia E; Pasquini, Ricardo; De Oliveira, Michel Michels; Velloso, Elvira D R P; Alter, Blanche P; Savage, Sharon A; Bonfim, Carmem; Wu, Colin O; Calado, Rodrigo T; Young, Neal S.

Blood ; 141(17): 2100-2113, 2023 04 27.

Artigo em Inglês | MEDLINE | ID: mdl-36542832

4.

Spectrum of clonal hematopoiesis in VEXAS syndrome.

Gutierrez-Rodrigues, Fernanda; Kusne, Yael; Fernandez, Jenna; Lasho, Terra; Shalhoub, Ruba; Ma, Xiaoyang; Alessi, Hugh; Finke, Christy; Koster, Matthew J; Mangaonkar, Abhishek; Warrington, Kenneth J; Begna, Kebede; Xie, Zhuoer; Ombrello, Amanda K; Viswanatha, David; Ferrada, Marcela; Wilson, Lorena; Go, Ronald; Kourelis, Taxiarchis; Reichard, Kaaren; Olteanu, Horatiu; Darden, Ivana; Hironaka, Dalton; Alemu, Lemlem; Kajigaya, Sachiko; Rosenzweig, Sofia; Calado, Rodrigo T; Groarke, Emma M; Kastner, Daniel L; Calvo, Katherine R; Wu, Colin O; Grayson, Peter C; Young, Neal S; Beck, David B; Patel, Bhavisha A; Patnaik, Mrinal M.

Blood ; 142(3): 244-259, 2023 07 20.

Artigo em Inglês | MEDLINE | ID: mdl-37084382

5.

Long-term outcomes in patients with severe aplastic anemia treated with immunosuppression and eltrombopag: a phase 2 study.

Patel, Bhavisha A; Groarke, Emma M; Lotter, Jennifer; Shalhoub, Ruba; Gutierrez-Rodrigues, Fernanda; Rios, Olga; Quinones Raffo, Diego; Wu, Colin O; Young, Neal S.

Blood ; 139(1): 34-43, 2022 01 06.

Artigo em Inglês | MEDLINE | ID: mdl-34525188

6.

Translation of cytoplasmic UBA1 contributes to VEXAS syndrome pathogenesis.

Ferrada, Marcela A; Savic, Sinisa; Cardona, Daniela Ospina; Collins, Jason C; Alessi, Hugh; Gutierrez-Rodrigues, Fernanda; Kumar, Dinesh Babu Uthaya; Wilson, Lorena; Goodspeed, Wendy; Topilow, James S; Paik, Julie J; Poulter, James A; Kermani, Tanaz A; Koster, Matthew J; Warrington, Kenneth J; Cargo, Catherine; Tattersall, Rachel S; Duncan, Christopher J A; Cantor, Anna; Hoffmann, Patrycja; Payne, Elspeth M; Bonnekoh, Hanna; Krause, Karoline; Cowen, Edward W; Calvo, Katherine R; Patel, Bhavisha A; Ombrello, Amanda K; Kastner, Daniel L; Young, Neal S; Werner, Achim; Grayson, Peter C; Beck, David B.

Blood ; 140(13): 1496-1506, 2022 09 29.

Artigo em Inglês | MEDLINE | ID: mdl-35793467

7.

VEXAS syndrome.

Grayson, Peter C; Patel, Bhavisha A; Young, Neal S.

Blood ; 137(26): 3591-3594, 2021 07 01.

Artigo em Inglês | MEDLINE | ID: mdl-33971000

8.

HLA associations, somatic loss of HLA expression, and clinical outcomes in immune aplastic anemia.

Zaimoku, Yoshitaka; Patel, Bhavisha A; Adams, Sharon D; Shalhoub, Ruba; Groarke, Emma M; Lee, Audrey Ai Chin; Kajigaya, Sachiko; Feng, Xingmin; Rios, Olga Julia; Eager, Holly; Alemu, Lemlem; Quinones Raffo, Diego; Wu, Colin O; Flegel, Willy A; Young, Neal S.

Blood ; 138(26): 2799-2809, 2021 12 30.

Artigo em Inglês | MEDLINE | ID: mdl-34724566

9.

Conditional survival and standardized mortality ratios of patients with severe aplastic anemia surviving at least one year after hematopoietic cell transplantation or immunosuppressive therapy.

Nakamura, Ryotaro; Patel, Bhavisha A; Kim, Soyoung; Wong, F Lennie; Armenian, Saro H; Groarke, Emma M; Keesler, Daniel A; Hebert, Kyle M; Heim, Michael; Eapen, Mary; Young, Neal S.

Haematologica ; 108(12): 3298-3307, 2023 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-37259612

10.

Granulocyte transfusions in severe aplastic anemia.

Rajput, Roma V; Shah, Vaani; Shalhoub, Ruba N; West-Mitchell, Kamille; Cha, Nu Ri; Conry-Cantilena, Cathy; Leitman, Susan F; Young, David J; Wells, Brian; Aue, Georg; Dunbar, Cynthia E; Patel, Bhavisha A; Childs, Richard W; Young, Neal S; Wu, Colin O; Groarke, Emma M; Kalsi, Shelley S.

Haematologica ; 2023 Dec 07.

Artigo em Inglês | MEDLINE | ID: mdl-38058170

11.

Alemtuzumab in relapsed immune severe aplastic anemia: Long-term results of a phase II study.

Aggarwal, Nidhi; Manley, Ash Lee; Shalhoub, Ruba; Durrani, Jibran; Rios, Olga; Lotter, Jennifer; Patel, Bhavisha A; Wu, Colin O; Young, Neal S; Groarke, Emma M.

Am J Hematol ; 98(6): 932-939, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37021397

12.

Clinical outcomes and immune responses to SARS-CoV-2 vaccination in severe aplastic anaemia.

Rajput, Roma V; Ma, Xiaoyang; Boswell, Kristin L; Gaudinski, Martin; Gordon, Ingelise; Novik, Laura; Groarke, Emma M; Lotter, Jennifer; Superata, Jeanine; Rios, Olga J; Darden, Ivana; Lin, Bob C; Jean-Baptiste, Nazaire; Carroll, Robin; Moore, Christopher; Trost, Jessica; Naisan, Mursal; Willis, Jacquelyn; Serebryannyy, Leonid; Wang, Jennifer L; Prabhakaran, Madhu; Narpala, Sandeep R; Koup, Richard A; McDermott, Adrian; Wu, Colin O; Young, Neal S; Patel, Bhavisha A.

Br J Haematol ; 199(5): 679-687, 2022 12.

Artigo em Inglês | MEDLINE | ID: mdl-36128909

13.

Predicting response of severe aplastic anemia to immunosuppression combined with eltrombopag.

Zaimoku, Yoshitaka; Patel, Bhavisha A; Shalhoub, Ruba; Groarke, Emma M; Feng, Xingmin; Wu, Colin O; Young, Neal S.

Haematologica ; 107(1): 126-133, 2022 01 01.

Artigo em Inglês | MEDLINE | ID: mdl-33910334

14.

Utility of plasma cell-free DNA for de novo detection and quantification of clonal hematopoiesis.

Gutierrez-Rodrigues, Fernanda; Beerman, Isabel; Groarke, Emma M; Patel, Bhavisha A; Spitofsky, Nina; Dillon, Laura W; Raffo, Diego Quinones; Hourigan, Christopher S; Kajigaya, Sachiko; Ferrucci, Luigi; Young, Neal S.

Haematologica ; 107(8): 1815-1826, 2022 08 01.

Artigo em Inglês | MEDLINE | ID: mdl-34587721

15.

Eltrombopag added to immunosuppression for children with treatment-naïve severe aplastic anaemia.

Groarke, Emma M; Patel, Bhavisha A; Gutierrez-Rodrigues, Fernanda; Rios, Olga; Lotter, Jennifer; Baldoni, Daniela; St Pierre, Annie; Shalhoub, Ruba; Wu, Colin O; Townsley, Danielle M; Young, Neal S.

Br J Haematol ; 192(3): 605-614, 2021 02.

Artigo em Inglês | MEDLINE | ID: mdl-33410523

16.

Deficit of circulating CD19⁺ CD24^hi CD38^hi regulatory B cells in severe aplastic anaemia.

Zaimoku, Yoshitaka; Patel, Bhavisha A; Kajigaya, Sachiko; Feng, Xingmin; Alemu, Lemlem; Quinones Raffo, Diego; Groarke, Emma M; Young, Neal S.

Br J Haematol ; 190(4): 610-617, 2020 08.

Artigo em Inglês | MEDLINE | ID: mdl-32311088

17.

Eltrombopag monotherapy can improve hematopoiesis in patients with low to intermediate risk-1 myelodysplastic syndrome.

Vicente, Alana; Patel, Bhavisha A; Gutierrez-Rodrigues, Fernanda; Groarke, Emma; Giudice, Valentina; Lotter, Jennifer; Feng, Xingmin; Kajigaya, Sachiko; Weinstein, Barbara; Barranta, Evette; Olnes, Matthew J; Parikh, Ankur R; Albitar, Maher; Wu, Colin O; Shalhoub, Ruba; Calvo, Katherine R; Townsley, Danielle M; Scheinberg, Phillip; Dunbar, Cynthia E; Young, Neal S; Winkler, Thomas.

Haematologica ; 105(12): 2785-2794, 2020 12 01.

Artigo em Inglês | MEDLINE | ID: mdl-33256377

18.

Ruxolitinib is more effective than other JAK inhibitors to treat VEXAS syndrome: a retrospective multicenter study.

Heiblig, Maël; Ferrada, Marcela A; Koster, Matthew J; Barba, Thomas; Gerfaud-Valentin, Mathieu; Mékinian, Arsène; Coelho, Henrique; Fossard, Gaelle; Barraco, Fiorenza; Galicier, Lionel; Bienvenu, Boris; Hirsch, Pierre; Vial, Guillaume; Boutin, Anne Blandine; Galland, Joris; Le Guenno, Guillaume; Bigot, Adrien; Warrington, Kenneth J; Kermani, Tanaz A; Grayson, Peter C; Patel, Bhavisha A; Beck, David B; Jamilloux, Yvan; Fenaux, Pierre; Sujobert, Pierre.

Blood ; 140(8): 927-931, 2022 08 25.

Artigo em Inglês | MEDLINE | ID: mdl-35609174

19.

Towards treatments for VEXAS.

Patel, Bhavisha A; Young, Neal S.

Br J Haematol ; 196(4): 804-805, 2022 02.

Artigo em Inglês | MEDLINE | ID: mdl-34729765

20.

COVID-19 infection in patients with severe aplastic anaemia.

Paton, Casey; Mathews, Liza; Groarke, Emma M; Rios, Olga; Lotter, Jennifer; Patel, Bhavisha A; Young, Neal S.

Br J Haematol ; 193(5): 902-905, 2021 06.

Artigo em Inglês | MEDLINE | ID: mdl-33928632

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