Detalhe da pesquisa
1.
Exploration of the P1 residue in 3CL protease inhibitors leading to the discovery of a 2-tetrahydrofuran P1 replacement.
Bioorg Med Chem
; 100: 117618, 2024 Feb 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38309201
2.
Novel tricyclics (e.g., GSK945237) as potent inhibitors of bacterial type IIA topoisomerases.
Bioorg Med Chem Lett
; 26(10): 2464-2469, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27055939
3.
Type IIA topoisomerase inhibition by a new class of antibacterial agents.
Nature
; 466(7309): 935-40, 2010 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-20686482
4.
Novel hydroxyl tricyclics (e.g., GSK966587) as potent inhibitors of bacterial type IIA topoisomerases.
Bioorg Med Chem Lett
; 23(19): 5437-41, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23968823
5.
Structural basis of quinolone inhibition of type IIA topoisomerases and target-mediated resistance.
Nat Struct Mol Biol
; 17(9): 1152-3, 2010 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-20802486
6.
Design and synthesis of conformationally restricted eight-Membered ring diketones as potential serine protease inhibitors.
Bioorg Med Chem Lett
; 12(17): 2359-62, 2002 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-12161133