Detalhe da pesquisa
1.
Experimental structure based drug design (SBDD) applications for anti-leishmanial drugs: A paradigm shift?
Med Res Rev
; 44(3): 1055-1120, 2024 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-38142308
2.
Novel amino analogs of the trimethoxyphenyl ring in potent colchicine site ligands improve solubility by the masked polar group incorporation (MPGI) strategy.
Bioorg Chem
; 131: 106282, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36459777
3.
Fast Parabolic Fitting: An R-Peak Detection Algorithm for Wearable ECG Devices.
Sensors (Basel)
; 23(21)2023 Oct 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-37960497
4.
Novel Tetrazole Derivatives Targeting Tubulin Endowed with Antiproliferative Activity against Glioblastoma Cells.
Int J Mol Sci
; 24(13)2023 Jul 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-37446273
5.
Identification of 7-Ketocholesterol-Modulated Pathways and Sterculic Acid Protective Effect in Retinal Pigmented Epithelium Cells by Using Genome-Wide Transcriptomic Analysis.
Int J Mol Sci
; 24(8)2023 Apr 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37108627
6.
Frentizole, a Nontoxic Immunosuppressive Drug, and Its Analogs Display Antitumor Activity via Tubulin Inhibition.
Int J Mol Sci
; 24(24)2023 Dec 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-38139302
7.
A Novel Framework for Generating Personalized Network Datasets for NIDS Based on Traffic Aggregation.
Sensors (Basel)
; 22(5)2022 Feb 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35270994
8.
Panobinostat Synergistically Enhances the Cytotoxicity of Microtubule Destabilizing Drugs in Ovarian Cancer Cells.
Int J Mol Sci
; 23(21)2022 Oct 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36361809
9.
New indolesulfonamide derivatives targeting the colchicine site of tubulin: synthesis, anti-tumour activity, structure-activity relationships, and molecular modelling.
J Enzyme Inhib Med Chem
; 36(1): 2025-2044, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34514909
10.
Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line.
J Enzyme Inhib Med Chem
; 36(1): 1029-1047, 2021 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-34107837
11.
Neuroprotective Effect of Apolipoprotein D in Cuprizone-Induced Cell Line Models: A Potential Therapeutic Approach for Multiple Sclerosis and Demyelinating Diseases.
Int J Mol Sci
; 22(3)2021 Jan 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-33514021
12.
Microtubule Destabilizing Sulfonamides as an Alternative to Taxane-Based Chemotherapy.
Int J Mol Sci
; 22(4)2021 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-33673002
13.
The Bateman domain of IMP dehydrogenase is a binding target for dinucleoside polyphosphates.
J Biol Chem
; 294(40): 14768-14775, 2019 10 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-31416831
14.
Potent colchicine-site ligands with improved intrinsic solubility by replacement of the 3,4,5-trimethoxyphenyl ring with a 2-methylsulfanyl-6-methoxypyridine ring.
Bioorg Chem
; 98: 103755, 2020 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-32200330
15.
Antitubulin sulfonamides: The successful combination of an established drug class and a multifaceted target.
Med Res Rev
; 39(3): 775-830, 2019 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-30362234
16.
Inflammatory and cell death mechanisms induced by 7-ketocholesterol in the retina. Implications for age-related macular degeneration.
Exp Eye Res
; 187: 107746, 2019 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31394101
17.
An Enhanced Lightweight IoT-based Authentication Scheme in Cloud Computing Circumstances.
Sensors (Basel)
; 19(9)2019 May 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31064133
18.
Segmentation of the ECG Signal by Means of a Linear Regression Algorithm.
Sensors (Basel)
; 19(4)2019 Feb 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-30769781
19.
In Silico Molecular Studies of Antiophidic Properties of the Amazonian Tree Cordia nodosa Lam.
Molecules
; 24(22)2019 Nov 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-31744153
20.
The Masked Polar Group Incorporation (MPGI) Strategy in Drug Design: Effects of Nitrogen Substitutions on Combretastatin and Isocombretastatin Tubulin Inhibitors.
Molecules
; 24(23)2019 Nov 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-31779228