Detalhe da pesquisa
1.
US regulations to curb alleged cancer causes are ineffectual and compromised by scientific, constitutional and ethical violations.
Arch Toxicol
; 97(6): 1813-1822, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37029818
2.
The EU chemicals strategy for sustainability: in support of the BfR position.
Arch Toxicol
; 95(9): 3133-3136, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34363510
3.
CYP-associated drug-drug interactions: A mission accomplished?
Arch Toxicol
; 94(11): 3931-3934, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33025068
4.
Inhibition and induction of CYP enzymes in humans: an update.
Arch Toxicol
; 94(11): 3671-3722, 2020 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-33111191
5.
Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity: how to evaluate the risk of the S-EDCs?
Arch Toxicol
; 94(7): 2549-2557, 2020 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-32514609
6.
Human exposure to synthetic endocrine disrupting chemicals (S-EDCs) is generally negligible as compared to natural compounds with higher or comparable endocrine activity. How to evaluate the risk of the S-EDCs?
J Toxicol Environ Health A
; 83(13-14): 485-494, 2020 07 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-32552445
7.
Integration of epidemiological findings with mechanistic evidence in regulatory pesticide risk assessment: EFSA experiences.
Arch Toxicol
; 93(6): 1779-1788, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-31053889
8.
Obfuscating transparency?
Regul Toxicol Pharmacol
; 97: A1-A3, 2018 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-30017904
9.
Chemical exposure and infant leukaemia: development of an adverse outcome pathway (AOP) for aetiology and risk assessment research.
Arch Toxicol
; 91(8): 2763-2780, 2017 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-28536863
10.
Tandem mass spectrometric analysis of S- and N-linked glutathione conjugates of pulegone and menthofuran and identification of P450 enzymes mediating their formation.
Rapid Commun Mass Spectrom
; 30(7): 917-26, 2016 Apr 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26969934
11.
PBTK modelling platforms and parameter estimation tools to enable animal-free risk assessment: recommendations from a joint EPAA--EURL ECVAM ADME workshop.
Regul Toxicol Pharmacol
; 68(1): 119-39, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-24287156
12.
Editorial.
Regul Toxicol Pharmacol
; 101: A1-A2, 2019 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-30642615
13.
Thujone and thujone-containing herbal medicinal and botanical products: toxicological assessment.
Regul Toxicol Pharmacol
; 65(1): 100-7, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23201408
14.
Effects of cytochrome P450 inhibitors and inducers on the metabolism and pharmacokinetics of ospemifene.
Biopharm Drug Dispos
; 34(7): 387-95, 2013 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-23852652
15.
Effects of ospemifene on drug metabolism mediated by cytochrome P450 enzymes in humans in vitro and in vivo.
Int J Mol Sci
; 14(7): 14064-75, 2013 Jul 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-23880855
16.
Inter-species differences between humans and other mammals in the in vitro metabolism of carbofuran and the role of human CYP enzymes.
Environ Toxicol Pharmacol
; 102: 104243, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37572996
17.
Statement of the Scientific Panel on Plant Protection Products and their Residues (PPR Panel) on the design and conduct of groundwater monitoring studies supporting groundwater exposure assessments of pesticides.
EFSA J
; 21(5): e07990, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-37197560
18.
Metabolites in the regulatory risk assessment of pesticides in the EU.
Front Toxicol
; 5: 1304885, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-38188093
19.
Development of adverse outcome pathways relevant for the identification of substances having endocrine disruption properties Uterine adenocarcinoma as adverse outcome.
EFSA J
; 21(2): e07744, 2023 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-36818642
20.
Characterization of furathiocarb metabolism in in-vitro human liver microsomes and recombinant cytochrome P450 enzymes.
Toxicol Rep
; 9: 679-689, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35399214