Detalhe da pesquisa
1.
Hepatitis C virus core protein uses triacylglycerols to fold onto the endoplasmic reticulum membrane.
Traffic
; 23(1): 63-80, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34729868
2.
NS2 proteases from hepatitis C virus and related hepaciviruses share composite active sites and previously unrecognized intrinsic proteolytic activities.
PLoS Pathog
; 14(2): e1006863, 2018 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-29415072
3.
The amino-terminus of the hepatitis C virus (HCV) p7 viroporin and its cleavage from glycoprotein E2-p7 precursor determine specific infectivity and secretion levels of HCV particle types.
PLoS Pathog
; 13(12): e1006774, 2017 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-29253880
4.
Overall Structural Model of NS5A Protein from Hepatitis C Virus and Modulation by Mutations Confering Resistance of Virus Replication to Cyclosporin A.
Biochemistry
; 56(24): 3029-3048, 2017 06 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-28535337
5.
Ion Channel Function and Cross-Species Determinants in Viral Assembly of Nonprimate Hepacivirus p7.
J Virol
; 90(10): 5075-5089, 2016 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-26962224
6.
The N-terminal Helical Region of the Hepatitis C Virus p7 Ion Channel Protein Is Critical for Infectious Virus Production.
PLoS Pathog
; 11(11): e1005297, 2015 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-26588073
7.
A Proline-Tryptophan Turn in the Intrinsically Disordered Domain 2 of NS5A Protein Is Essential for Hepatitis C Virus RNA Replication.
J Biol Chem
; 290(31): 19104-20, 2015 Jul 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-26085105
8.
Cell-free expression, purification, and membrane reconstitution for NMR studies of the nonstructural protein 4B from hepatitis C virus.
J Biomol NMR
; 65(2): 87-98, 2016 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27233794
9.
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion.
J Virol
; 89(20): 10333-46, 2015 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-26246575
10.
Aminoterminal amphipathic α-helix AH1 of hepatitis C virus nonstructural protein 4B possesses a dual role in RNA replication and virus production.
PLoS Pathog
; 10(10): e1004501, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25392992
11.
Assessing the physiological relevance of alternate architectures of the p7 protein of hepatitis C virus in different environments.
Bioorg Med Chem
; 24(20): 4920-4927, 2016 10 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-27501910
12.
Daclatasvir-like inhibitors of NS5A block early biogenesis of hepatitis C virus-induced membranous replication factories, independent of RNA replication.
Gastroenterology
; 147(5): 1094-105.e25, 2014 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-25046163
13.
NS2 proteins of GB virus B and hepatitis C virus share common protease activities and membrane topologies.
J Virol
; 88(13): 7426-44, 2014 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-24741107
14.
Determinants for membrane association of the hepatitis C virus NS2 protease domain.
J Virol
; 88(11): 6519-23, 2014 Jun.
Artigo
em Inglês
| MEDLINE | ID: mdl-24648458
15.
Identification of conserved residues in hepatitis C virus envelope glycoprotein E2 that modulate virus dependence on CD81 and SRB1 entry factors.
J Virol
; 88(18): 10584-97, 2014 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-24990994
16.
Quantitative proteomics identifies the membrane-associated peroxidase GPx8 as a cellular substrate of the hepatitis C virus NS3-4A protease.
Hepatology
; 59(2): 423-33, 2014 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23929719
17.
Wheat germ cell-free expression: Two detergents with a low critical micelle concentration allow for production of soluble HCV membrane proteins.
Protein Expr Purif
; 105: 39-46, 2015 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-25306874
18.
Functional expression, purification, characterization, and membrane reconstitution of non-structural protein 2 from hepatitis C virus.
Protein Expr Purif
; 116: 1-6, 2015 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-26325423
19.
Disulfide bonds in hepatitis C virus glycoprotein E1 control the assembly and entry functions of E2 glycoprotein.
J Virol
; 87(3): 1605-17, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23175356
20.
Analysis of hepatitis C virus resistance to silibinin in vitro and in vivo points to a novel mechanism involving nonstructural protein 4B.
Hepatology
; 57(3): 953-63, 2013 Mar.
Artigo
em Inglês
| MEDLINE | ID: mdl-23322644