Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.

Penn, Bennett H; Netter, Zoe; Johnson, Jeffrey R; Von Dollen, John; Jang, Gwendolyn M; Johnson, Tasha; Ohol, Yamini M; Maher, Cyrus; Bell, Samantha L; Geiger, Kristina; Golovkine, Guillaume; Du, Xiaotang; Choi, Alex; Parry, Trevor; Mohapatra, Bhopal C; Storck, Matthew D; Band, Hamid; Chen, Chen; Jäger, Stefanie; Shales, Michael; Portnoy, Dan A; Hernandez, Ryan; Coscoy, Laurent; Cox, Jeffery S; Krogan, Nevan J.

Mol Cell ; 71(4): 637-648.e5, 2018 08 16.

Artigo em Inglês | MEDLINE | ID: mdl-30118682

2.

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

Morrison, Huntly M; Craft, Julia; Rivera-Lugo, Rafael; Johnson, Jeffery R; Golovkine, Guillaume R; Bell, Samantha L; Dodd, Claire E; Van Dis, Erik; Beatty, Wandy L; Margolis, Shally R; Repasy, Teresa; Shaker, Isaac; Lee, Angus Y; Vance, Russell E; Stanley, Sarah A; Watson, Robert O; Krogan, Nevan J; Portnoy, Daniel A; Penn, Bennett H; Cox, Jeffery S.

PLoS Pathog ; 19(6): e1011088, 2023 06.

Artigo em Inglês | MEDLINE | ID: mdl-37352334

3.

Successful treatment of neurocysticercosis with albendazole desensitization.

Nguyen, Anh P; Hoffman, Wesley; Penn, Bennett H; Pham, David; Teuber, Suzanne S.

Asian Pac J Allergy Immunol ; 2021 Feb 21.

Artigo em Inglês | MEDLINE | ID: mdl-33638628

4.

Immunology: Organelle stress triggers inflammation.

Penn, Bennett H; Cox, Jeffery S.

Nature ; 532(7599): 321-2, 2016 Apr 21.

Artigo em Inglês | MEDLINE | ID: mdl-27049940

5.

The balance between antiviral and antibacterial responses during M. tuberculosis infection is regulated by the ubiquitin ligase CBL.

Truong, Tina; Martin, Kelsey E; Salemi, Michelle R; Ray, Abigail E; Phinney, Brett S; Penn, Bennett H.

bioRxiv ; 2024 May 23.

Artigo em Inglês | MEDLINE | ID: mdl-38798543

6.

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang, Yifan; Hollingsworth, L Robert; Sangaré, Lamba Omar; Paredes-Santos, Tatiana C; Krishnamurthy, Shruthi; Penn, Bennett H; Wu, Hao; Saeij, Jeroen P J.

mBio ; 15(3): e0330223, 2024 Mar 13.

Artigo em Inglês | MEDLINE | ID: mdl-38376248

7.

High-Efficiency Gene Disruption in Primary Bone Marrow-Derived Macrophages Using Electroporated Cas9-sgRNA Complexes.

Craft, Julia; Truong, Tina; Penn, Bennett H.

J Vis Exp ; (198)2023 08 04.

Artigo em Inglês | MEDLINE | ID: mdl-37590503

8.

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Wang, Yifan; Hollingsworth, L Robert; Sangaré, Lamba Omar; Paredes-Santos, Tatiana C; Krishnamurthy, Shruthi; Penn, Bennett H; Wu, Hao; Saeij, Jeroen P J.

bioRxiv ; 2023 Dec 14.

Artigo em Inglês | MEDLINE | ID: mdl-38168400

9.

Investigation of nosocomial SARS-CoV-2 transmission from two patients to healthcare workers identifies close contact but not airborne transmission events.

Bays, Derek J; Nguyen, Minh-Vu H; Cohen, Stuart H; Waldman, Sarah; Martin, Carla S; Thompson, George R; Sandrock, Christian; Tourtellotte, Joel; Pugashetti, Janelle Vu; Phan, Chinh; Nguyen, Hien H; Warner, Gregory Y; Penn, Bennett H.

Infect Control Hosp Epidemiol ; 42(9): 1046-1052, 2021 09.

Artigo em Inglês | MEDLINE | ID: mdl-32618530

10.

An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein.

Truong, Tina; Penn, Bennett H.

Cell Host Microbe ; 27(3): 310-312, 2020 03 11.

Artigo em Inglês | MEDLINE | ID: mdl-32164839

11.

Traveling as a risk factor for venous thromboembolic disease.

Ercegovac, Una C; Metcalfe, Tracee L; Penn, Bennett H; Smith, Kelly M; Elmore, Joann G.

Respir Care ; 51(10): 1177-80, 2006 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-17044147

12.

Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters.

Cao, Yi; Kumar, Roshan M; Penn, Bennett H; Berkes, Charlotte A; Kooperberg, Charles; Boyer, Laurie A; Young, Richard A; Tapscott, Stephen J.

EMBO J ; 25(3): 502-11, 2006 Feb 08.

Artigo em Inglês | MEDLINE | ID: mdl-16437161

13.

A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation.

Penn, Bennett H; Bergstrom, Donald A; Dilworth, F Jeffrey; Bengal, Eyal; Tapscott, Stephen J.

Genes Dev ; 18(19): 2348-53, 2004 Oct 01.

Artigo em Inglês | MEDLINE | ID: mdl-15466486

14.

Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression.

Bergstrom, Donald A; Penn, Bennett H; Strand, Andrew; Perry, Robert L S; Rudnicki, Michael A; Tapscott, Stephen J.

Mol Cell ; 9(3): 587-600, 2002 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-11931766

15.

Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential.

Berkes, Charlotte A; Bergstrom, Donald A; Penn, Bennett H; Seaver, Karen J; Knoepfler, Paul S; Tapscott, Stephen J.

Mol Cell ; 14(4): 465-77, 2004 May 21.

Artigo em Inglês | MEDLINE | ID: mdl-15149596

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An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.

Deficiency in Galectin-3, -8, and -9 impairs immunity to chronic Mycobacterium tuberculosis infection but not acute infection with multiple intracellular pathogens.

Successful treatment of neurocysticercosis with albendazole desensitization.

Immunology: Organelle stress triggers inflammation.

The balance between antiviral and antibacterial responses during M. tuberculosis infection is regulated by the ubiquitin ligase CBL.

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

High-Efficiency Gene Disruption in Primary Bone Marrow-Derived Macrophages Using Electroporated Cas9-sgRNA Complexes.

Host E3 ubiquitin ligase ITCH mediates Toxoplasma gondii effector GRA35-triggered NLRP1 inflammasome activation and cell-autonomous immunity.

Investigation of nosocomial SARS-CoV-2 transmission from two patients to healthcare workers identifies close contact but not airborne transmission events.

An M. tuberculosis Metabolic Enzyme Moonlights as an Anti-Inflammatory Effector Protein.

Traveling as a risk factor for venous thromboembolic disease.

Global and gene-specific analyses show distinct roles for Myod and Myog at a common set of promoters.

A MyoD-generated feed-forward circuit temporally patterns gene expression during skeletal muscle differentiation.

Promoter-specific regulation of MyoD binding and signal transduction cooperate to pattern gene expression.

Pbx marks genes for activation by MyoD indicating a role for a homeodomain protein in establishing myogenic potential.