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1.
Sensors (Basel) ; 23(16)2023 Aug 11.
Artigo em Inglês | MEDLINE | ID: mdl-37631646

RESUMO

Regular inspections during construction work ensure that the completed work aligns with the plans and specifications and that it is within the planned time and budget. This requires frequent physical site observations to independently measure and verify the completion percentage of the construction progress performed over periods of time. The current computer vision techniques for measuring as-built elements predominantly employ three-dimensional laser scanning or three-dimensional photogrammetry modeling to ascertain the geometric properties of as-built elements on construction sites. Both techniques require data acquisition from several positions and angles to generate sufficient information about the element's coordinates, making the deployment of these techniques on dynamic construction project sites challenging. This paper proposes a pipeline for automating the measurement of as-built components using artificial intelligence and computer vision techniques. The pipeline requires a single image obtained with a stereo camera system to measure the sizes of selected objects or as-built components. The results in this work were demonstrated by measuring the sizes of concrete walls and columns. The novelty of this work is attributed to the use of a single image and a single target for developing a fully automated computer vision-based method for measuring any given object. The proposed solution is suitable for use in measuring the sizes of as-built components in built assets. It has the potential to be further developed and integrated with building information modelling applications for use on construction projects for progress monitoring.

2.
Br J Cancer ; 122(8): 1231-1241, 2020 04.
Artigo em Inglês | MEDLINE | ID: mdl-32147670

RESUMO

BACKGROUND: Genome-wide association studies (GWASs) have enriched the fields of genomics and drug development. Adrenocortical carcinoma (ACC) is a rare cancer with a bimodal age distribution and inadequate treatment options. Paediatric ACC is frequently associated with TP53 mutations, with particularly high incidence in Southern Brazil due to the TP53 p.R337H (R337H) germline mutation. The heterogeneous risk among carriers suggests other genetic modifiers could exist. METHODS: We analysed clinical, genotype and gene expression data derived from paediatric ACC, R337H carriers, and adult ACC patients. We restricted our analyses to single nucleotide polymorphisms (SNPs) previously identified in GWASs to associate with disease or human traits. RESULTS: A SNP, rs971074, in the alcohol dehydrogenase 7 gene significantly and reproducibly associated with allelic differences in ACC age-of-onset in both cohorts. Patients homozygous for the minor allele were diagnosed up to 16 years earlier. This SNP resides in a gene involved in the retinoic acid (RA) pathway and patients with differing levels of RA pathway gene expression in their tumours associate with differential ACC progression. CONCLUSIONS: These results identify a novel genetic component to ACC development that resides in the retinoic acid pathway, thereby informing strategies to develop management, preventive and therapeutic treatments for ACC.


Assuntos
Neoplasias do Córtex Suprarrenal/genética , Carcinoma Adrenocortical/genética , Genes p53 , Polimorfismo de Nucleotídeo Único , Tretinoína/fisiologia , Adolescente , Neoplasias do Córtex Suprarrenal/epidemiologia , Carcinoma Adrenocortical/epidemiologia , Fatores Etários , Idade de Início , Álcool Desidrogenase/genética , Criança , Pré-Escolar , Feminino , Estudo de Associação Genômica Ampla , Humanos , Incidência , Lactente , Masculino
3.
Sensors (Basel) ; 19(16)2019 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-31443244

RESUMO

Clients are increasingly looking for fast and effective means to quickly and frequently survey and communicate the condition of their buildings so that essential repairs and maintenance work can be done in a proactive and timely manner before it becomes too dangerous and expensive. Traditional methods for this type of work commonly comprise of engaging building surveyors to undertake a condition assessment which involves a lengthy site inspection to produce a systematic recording of the physical condition of the building elements, including cost estimates of immediate and projected long-term costs of renewal, repair and maintenance of the building. Current asset condition assessment procedures are extensively time consuming, laborious, and expensive and pose health and safety threats to surveyors, particularly at height and roof levels which are difficult to access. This paper aims at evaluating the application of convolutional neural networks (CNN) towards an automated detection and localisation of key building defects, e.g., mould, deterioration, and stain, from images. The proposed model is based on pre-trained CNN classifier of VGG-16 (later compaired with ResNet-50, and Inception models), with class activation mapping (CAM) for object localisation. The challenges and limitations of the model in real-life applications have been identified. The proposed model has proven to be robust and able to accurately detect and localise building defects. The approach is being developed with the potential to scale-up and further advance to support automated detection of defects and deterioration of buildings in real-time using mobile devices and drones.

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