Detalhe da pesquisa
1.
The conformational signature of ß-arrestin2 predicts its trafficking and signalling functions.
Nature
; 531(7596): 665-8, 2016 Mar 31.
Artigo
em Inglês
| MEDLINE | ID: mdl-27007854
2.
Application of Pharmacokinetic Prediction Platforms in the Design of Optimized Anti-Cancer Drugs.
Molecules
; 27(12)2022 Jun 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35744803
3.
Receptor-interacting Ser/Thr kinase 1 (RIPK1) and myosin IIA-dependent ceramidosomes form membrane pores that mediate blebbing and necroptosis.
J Biol Chem
; 294(2): 502-519, 2019 01 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-30420430
4.
The NMR-based characterization of the FTY720-SET complex reveals an alternative mechanism for the attenuation of the inhibitory SET-PP2A interaction.
FASEB J
; 33(6): 7647-7666, 2019 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-30917007
5.
The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
Pharmacol Rev
; 69(3): 256-297, 2017 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-28626043
6.
Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo.
Ann Surg Oncol
; 26(13): 4782-4790, 2019 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-31515721
7.
Frizzled-5: a high affinity receptor for secreted frizzled-related protein-2 activation of nuclear factor of activated T-cells c3 signaling to promote angiogenesis.
Angiogenesis
; 20(4): 615-628, 2017 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-28840375
8.
Quantitative analysis of mitochondrial morphology and membrane potential in living cells using high-content imaging, machine learning, and morphological binning.
Biochim Biophys Acta
; 1853(2): 348-60, 2015 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-25447550
9.
The arrestin-selective angiotensin AT1 receptor agonist [Sar1,Ile4,Ile8]-AngII negatively regulates bradykinin B2 receptor signaling via AT1-B2 receptor heterodimers.
J Biol Chem
; 288(26): 18872-84, 2013 Jun 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-23661707
10.
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy.
Nat Chem Biol
; 8(10): 831-8, 2012 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-22922758
11.
Development of inhibitors of heterotrimeric Gαi subunits.
Bioorg Med Chem
; 22(13): 3423-34, 2014 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24818958
12.
Inhibition of complement C3 prevents osteoarthritis progression in guinea pigs by blocking STAT1 activation.
Commun Biol
; 7(1): 370, 2024 Mar 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-38538870
13.
Opportunistic pathogen Porphyromonas gingivalis targets the LC3B-ceramide complex and mediates lethal mitophagy resistance in oral tumors.
iScience
; 27(6): 109860, 2024 Jun 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-38779482
14.
High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury.
Toxicol Appl Pharmacol
; 272(2): 490-502, 2013 Oct 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-23811330
15.
ß2-Adrenoceptor agonists in the regulation of mitochondrial biogenesis.
Bioorg Med Chem Lett
; 23(19): 5376-81, 2013 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-23954364
16.
Bax and Bcl-xL exert their regulation on different sites of the ceramide channel.
Biochem J
; 445(1): 81-91, 2012 Jul 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22494048
17.
A high-content, live-cell, and real-time approach to the quantitation of ligand-induced ß-Arrestin2 and Class A/Class B GPCR mobilization.
Microsc Microanal
; 19(1): 150-70, 2013 Feb.
Artigo
em Inglês
| MEDLINE | ID: mdl-23351552
18.
Stimulation of natural killer cells with small molecule inhibitors of CD38 for the treatment of neuroblastoma.
Chem Sci
; 14(8): 2168-2182, 2023 Feb 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-36845935
19.
A human iPSC-derived hepatocyte screen identifies compounds that inhibit production of Apolipoprotein B.
Commun Biol
; 6(1): 452, 2023 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-37095219
20.
The ß2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis.
J Pharmacol Exp Ther
; 342(1): 106-18, 2012 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-22490378