Detalhe da pesquisa
1.
Combination drug screen identifies synergistic drug interaction of BCL-XL and class I histone deacetylase inhibitors in MYC-amplified medulloblastoma cells.
J Neurooncol
; 166(1): 99-112, 2024 Jan.
Artigo
em Inglês
| MEDLINE | ID: mdl-38184819
2.
Class I HDAC inhibition reduces DNA damage repair capacity of MYC-amplified medulloblastoma cells.
J Neurooncol
; 164(3): 617-632, 2023 Sep.
Artigo
em Inglês
| MEDLINE | ID: mdl-37783879
3.
iTReX: Interactive exploration of mono- and combination therapy dose response profiling data.
Pharmacol Res
; 175: 105996, 2022 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-34848323
4.
PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum.
Acta Neuropathol
; 142(5): 841-857, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34417833
5.
An advanced glioma cell invasion assay based on organotypic brain slice cultures.
BMC Cancer
; 18(1): 103, 2018 01 30.
Artigo
em Inglês
| MEDLINE | ID: mdl-29378533
6.
Neutralization of the CD95 ligand by APG101 inhibits invasion of glioma cells in vitro.
Anticancer Drugs
; 26(7): 716-27, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-25850884
7.
KIAA1797/FOCAD encodes a novel focal adhesion protein with tumour suppressor function in gliomas.
Brain
; 135(Pt 4): 1027-41, 2012 Apr.
Artigo
em Inglês
| MEDLINE | ID: mdl-22427331
8.
Evaluation of Antitumor and On-Target Activity of HDAC Inhibitors with the Zebrafish Embryo Xenograft Model.
Methods Mol Biol
; 2589: 75-85, 2023.
Artigo
em Inglês
| MEDLINE | ID: mdl-36255618
9.
ERBB and P-glycoprotein inhibitors break resistance in relapsed neuroblastoma models through P-glycoprotein.
Mol Oncol
; 17(1): 37-58, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-36181342
10.
Key Pharmacokinetic Parameters of 74 Pediatric Anticancer Drugs Providing Assistance in Preclinical Studies.
Clin Pharmacol Ther
; 114(4): 904-913, 2023 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-37441736
11.
The first-in-class ERK inhibitor ulixertinib shows promising activity in mitogen-activated protein kinase (MAPK)-driven pediatric low-grade glioma models.
Neuro Oncol
; 25(3): 566-579, 2023 03 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-35882450
12.
BH3 mimetics targeting BCL-XL impact the senescent compartment of pilocytic astrocytoma.
Neuro Oncol
; 25(4): 735-747, 2023 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-35977048
13.
Patient-by-Patient Deep Transfer Learning for Drug-Response Profiling Using Confocal Fluorescence Microscopy of Pediatric Patient-Derived Tumor-Cell Spheroids.
IEEE Trans Med Imaging
; 41(12): 3981-3999, 2022 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-36099221
14.
Predictive modeling of resistance to SMO inhibition in a patient-derived orthotopic xenograft model of SHH medulloblastoma.
Neurooncol Adv
; 4(1): vdac026, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35475274
15.
CD44 expressed by myeloid cells promotes glioma invasion.
Front Oncol
; 12: 969787, 2022.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992852
16.
Functional Therapeutic Target Validation Using Pediatric Zebrafish Xenograft Models.
Cancers (Basel)
; 14(3)2022 Feb 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-35159116
17.
Drug sensitivity profiling of 3D tumor tissue cultures in the pediatric precision oncology program INFORM.
NPJ Precis Oncol
; 6(1): 94, 2022 Dec 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-36575299
18.
Broad-Spectrum HDAC Inhibitors Promote Autophagy through FOXO Transcription Factors in Neuroblastoma.
Cells
; 10(5)2021 04 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33923163
19.
A Set of Cell Lines Derived from a Genetic Murine Glioblastoma Model Recapitulates Molecular and Morphological Characteristics of Human Tumors.
Cancers (Basel)
; 13(2)2021 Jan 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-33435218
20.
Combining APR-246 and HDAC-Inhibitors: A Novel Targeted Treatment Option for Neuroblastoma.
Cancers (Basel)
; 13(17)2021 Sep 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-34503286