Pesquisa | BVS Doenças Infecciosas e Parasitárias

1.

Effect of delayed-release dimethyl fumarate on no evidence of disease activity in relapsing-remitting multiple sclerosis: integrated analysis of the phase III DEFINE and CONFIRM studies.

Havrdova, E; Giovannoni, G; Gold, R; Fox, R J; Kappos, L; Phillips, J Theodore; Okwuokenye, M; Marantz, J L.

Eur J Neurol ; 24(5): 726-733, 2017 May.

Artigo em Inglês | MEDLINE | ID: mdl-28328179

2.

Placebo-controlled phase 3 study of oral BG-12 or glatiramer in multiple sclerosis.

Fox, Robert J; Miller, David H; Phillips, J Theodore; Hutchinson, Michael; Havrdova, Eva; Kita, Mariko; Yang, Minhua; Raghupathi, Kartik; Novas, Mark; Sweetser, Marianne T; Viglietta, Vissia; Dawson, Katherine T.

N Engl J Med ; 367(12): 1087-97, 2012 Sep 20.

Artigo em Inglês | MEDLINE | ID: mdl-22992072

3.

Efficacy and safety of delayed-release dimethyl fumarate in patients newly diagnosed with relapsing-remitting multiple sclerosis (RRMS).

Gold, Ralf; Giovannoni, Gavin; Phillips, J Theodore; Fox, Robert J; Zhang, Annie; Meltzer, Leslie; Kurukulasuriya, Nuwan C.

Mult Scler ; 21(1): 57-66, 2015 Jan.

Artigo em Inglês | MEDLINE | ID: mdl-24990854

4.

Effects of BG-12 (dimethyl fumarate) on health-related quality of life in patients with relapsing-remitting multiple sclerosis: findings from the CONFIRM study.

Kita, Mariko; Fox, Robert J; Phillips, J Theodore; Hutchinson, Michael; Havrdova, Eva; Sarda, Sujata P; Agarwal, Sonalee; Kong, Jessica; Zhang, Annie; Viglietta, Vissia; Sheikh, Sarah I; Seidman, Emily; Dawson, Katherine T.

Mult Scler ; 20(2): 253-7, 2014 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-24150778

5.

BG-12 in multiple sclerosis.

Phillips, J Theodore; Fox, Robert J.

Semin Neurol ; 33(1): 56-65, 2013 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-23709213

6.

Sustained improvement in Expanded Disability Status Scale as a new efficacy measure of neurological change in multiple sclerosis: treatment effects with natalizumab in patients with relapsing multiple sclerosis.

Phillips, J Theodore; Giovannoni, Gavin; Lublin, Fred D; O'Connor, Paul W; Polman, Chris H; Willoughby, Ernie; Aschenbach, William; Pace, Amy; Hyde, Robert; Munschauer, Frederick E.

Mult Scler ; 17(8): 970-9, 2011 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-21421809

7.

An open-label, multicenter study to evaluate the safe and effective use of the single-use autoinjector with an Avonex® prefilled syringe in multiple sclerosis subjects.

Phillips, J Theodore; Fox, Edward; Grainger, William; Tuccillo, Dianne; Liu, Shifang; Deykin, Aaron.

BMC Neurol ; 11: 126, 2011 Oct 14.

Artigo em Inglês | MEDLINE | ID: mdl-21999176

8.

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data.

Altman, Matthew C; Rinchai, Darawan; Baldwin, Nicole; Toufiq, Mohammed; Whalen, Elizabeth; Garand, Mathieu; Syed Ahamed Kabeer, Basirudeen; Alfaki, Mohamed; Presnell, Scott R; Khaenam, Prasong; Ayllón-Benítez, Aaron; Mougin, Fleur; Thébault, Patricia; Chiche, Laurent; Jourde-Chiche, Noemie; Phillips, J Theodore; Klintmalm, Goran; O'Garra, Anne; Berry, Matthew; Bloom, Chloe; Wilkinson, Robert J; Graham, Christine M; Lipman, Marc; Lertmemongkolchai, Ganjana; Bedognetti, Davide; Thiebaut, Rodolphe; Kheradmand, Farrah; Mejias, Asuncion; Ramilo, Octavio; Palucka, Karolina; Pascual, Virginia; Banchereau, Jacques; Chaussabel, Damien.

Nat Commun ; 12(1): 4385, 2021 07 19.

Artigo em Inglês | MEDLINE | ID: mdl-34282143

9.

Effect of natalizumab on clinical and radiological disease activity in multiple sclerosis: a retrospective analysis of the Natalizumab Safety and Efficacy in Relapsing-Remitting Multiple Sclerosis (AFFIRM) study.

Havrdova, Eva; Galetta, Steven; Hutchinson, Michael; Stefoski, Dusan; Bates, David; Polman, Chris H; O'Connor, Paul W; Giovannoni, Gavin; Phillips, J Theodore; Lublin, Fred D; Pace, Amy; Kim, Richard; Hyde, Robert.

Lancet Neurol ; 8(3): 254-60, 2009 Mar.

Artigo em Inglês | MEDLINE | ID: mdl-19201654

10.

A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis.

Polman, Chris H; O'Connor, Paul W; Havrdova, Eva; Hutchinson, Michael; Kappos, Ludwig; Miller, David H; Phillips, J Theodore; Lublin, Fred D; Giovannoni, Gavin; Wajgt, Andrzej; Toal, Martin; Lynn, Frances; Panzara, Michael A; Sandrock, Alfred W.

N Engl J Med ; 354(9): 899-910, 2006 Mar 02.

Artigo em Inglês | MEDLINE | ID: mdl-16510744

11.

Real-World Characterization of Dimethyl Fumarate-Related Gastrointestinal Events in Multiple Sclerosis: Management Strategies to Improve Persistence on Treatment and Patient Outcomes.

Min, Jinny; Cohan, Stanley; Alvarez, Enrique; Sloane, Jacob; Phillips, J Theodore; van der Walt, Anneke; Koulinska, Irene; Fang, Fang; Miller, Catherine; Chan, Andrew.

Neurol Ther ; 8(1): 109-119, 2019 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-30706431

12.

Effect of dimethyl fumarate on lymphocytes in RRMS: Implications for clinical practice.

Mehta, Devangi; Miller, Catherine; Arnold, Douglas L; Bame, Eris; Bar-Or, Amit; Gold, Ralf; Hanna, Jerome; Kappos, Ludwig; Liu, Shifang; Matta, André; Phillips, J Theodore; Robertson, Derrick; von Hehn, Christian A; Campbell, Jordana; Spach, Karen; Yang, Lili; Fox, Robert J.

Neurology ; 92(15): e1724-e1738, 2019 04 09.

Artigo em Inglês | MEDLINE | ID: mdl-30918100

13.

Health-related quality of life in multiple sclerosis: effects of natalizumab.

Rudick, Richard A; Miller, Deborah; Hass, Steve; Hutchinson, Michael; Calabresi, Peter A; Confavreux, Christian; Galetta, Steven L; Giovannoni, Gavin; Havrdova, Eva; Kappos, Ludwig; Lublin, Fred D; Miller, David H; O'Connor, Paul W; Phillips, J Theodore; Polman, Chris H; Radue, Ernst-Wilhelm; Stuart, William H; Wajgt, Andrzej; Weinstock-Guttman, Bianca; Wynn, Daniel R; Lynn, Frances; Panzara, Michael A.

Ann Neurol ; 62(4): 335-46, 2007 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-17696126

14.

Potential risk of progressive multifocal leukoencephalopathy with natalizumab therapy: possible interventions.

Stüve, Olaf; Marra, Christina M; Cravens, Petra D; Singh, Mahendra P; Hu, Wei; Lovett-Racke, Amy; Monson, Nancy L; Phillips, J Theodore; Tervaert, Jan W Cohen; Nash, Richard A; Hartung, Hans-Peter; Kieseier, Bernd C; Racke, Michael M; Frohman, Elliot M; Hemmer, Bernhard.

Arch Neurol ; 64(2): 169-76, 2007 Feb.

Artigo em Inglês | MEDLINE | ID: mdl-17296831

15.

Dimethyl Fumarate: A Review of Efficacy and Practical Management Strategies for Common Adverse Events in Patients with Multiple Sclerosis.

Phillips, J Theodore; Agrella, Stephanie; Fox, Robert J.

Int J MS Care ; 19(2): 74-83, 2017.

Artigo em Inglês | MEDLINE | ID: mdl-32607065

16.

Efficacy and Tolerability of Delayed-release Dimethyl Fumarate in Black, Hispanic, and Asian Patients with Relapsing-Remitting Multiple Sclerosis: Post Hoc Integrated Analysis of DEFINE and CONFIRM.

Fox, Robert J; Gold, Ralf; Phillips, J Theodore; Okwuokenye, Macaulay; Zhang, Annie; Marantz, Jing L.

Neurol Ther ; 6(2): 175-187, 2017 Dec.

Artigo em Inglês | MEDLINE | ID: mdl-28770420

17.

Efficacy and Safety of Delayed-release Dimethyl Fumarate for Relapsing-remitting Multiple Sclerosis in Prior Interferon Users: An Integrated Analysis of DEFINE and CONFIRM.

Fernández, Óscar; Giovannoni, Gavin; Fox, Robert J; Gold, Ralf; Phillips, J Theodore; Potts, James; Okwuokenye, Macaulay; Marantz, Jing L.

Clin Ther ; 39(8): 1671-1679, 2017 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-28751099

18.

Altered CD4+/CD8+ T-cell ratios in cerebrospinal fluid of natalizumab-treated patients with multiple sclerosis.

Stüve, Olaf; Marra, Christina M; Bar-Or, Amit; Niino, Masaaki; Cravens, Petra D; Cepok, Sabine; Frohman, Elliot M; Phillips, J Theodore; Arendt, Gabriele; Jerome, Keith R; Cook, Linda; Grand'Maison, Francois; Hemmer, Bernhard; Monson, Nancy L; Racke, Michael K.

Arch Neurol ; 63(10): 1383-7, 2006 Oct.

Artigo em Inglês | MEDLINE | ID: mdl-17030653

19.

Consensus opinion of US neurologists on practice patterns in RIS, CIS, and RRMS: Evolution of treatment practices.

Tornatore, Carlo; Phillips, J Theodore; Khan, Omar; Miller, Aaron E; Hughes, Mark.

Neurol Clin Pract ; 6(4): 329-338, 2016 Aug.

Artigo em Inglês | MEDLINE | ID: mdl-27574570

20.

Sustained Effect of Delayed-Release Dimethyl Fumarate in Newly Diagnosed Patients with Relapsing-Remitting Multiple Sclerosis: 6-Year Interim Results From an Extension of the DEFINE and CONFIRM Studies.

Gold, Ralf; Giovannoni, Gavin; Phillips, J Theodore; Fox, Robert J; Zhang, Annie; Marantz, Jing L.

Neurol Ther ; 5(1): 45-57, 2016 Jun.

Artigo em Inglês | MEDLINE | ID: mdl-26932146

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